Patents by Inventor Friedrich Loebich

Friedrich Loebich has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Pyrazinoisoquinolines as anthelmintic agents
    Patent number: 3993760
    Abstract: (-)-2-Benzoyl-4-oxo-1,2,3,6,7,11b-hexahydro-4H-pyrazino[2,1-a]isoquinoline is prepared by benzoylation of (-)-4-oxo-1,2,3,6,7,11b-hexahydro-4H-pyrazino[2,1-a]isoquinoline, or cyclization of a compound of the formula ##SPC1##Wherein X is F, Cl, Br, I or O-tosyl and which has the optical configuration of the final product, or cyclization of a compound of the formula ##SPC2## wherein Y is OH, alkoxy, F, Cl, Br or I under HY-removing reaction conditions and which has the optical configuration of the final product, which is an anthelmintic.
    Type: Grant
    Filed: June 21, 1974
    Date of Patent: November 23, 1976
    Assignee: Merck Patent Gesellschaft mit beschrankter Haftung
    Inventors: Rolf Pohlke, Friedrich Loebich, Jurgen Seubert, Herbert Thomas, Peter Andrews
  • Anthelmintic
    Patent number: 3993759
    Abstract: 2-Benzoyl-4-oxo-1,2,3,6,7,11b-hexahydro-4H-pyrazino[2,1-a]isoquinoline is used as an anthelmintic against cestodes and trematodes, preferably in admixture with a pharmaceutically acceptable carrier.
    Type: Grant
    Filed: March 11, 1974
    Date of Patent: November 23, 1976
    Assignee: Merck Patent Gesellschaft mit beschrankter Haftung
    Inventors: Rolf Pohlke, Friedrich Loebich, Herbert Thomas, Jurgen Thyssen