Abstract: A microplate reader comprises a housing; at least one optical measuring/detection device; a microplate support; a moving unit; and an integrated lid holding apparatus. The lid holding apparatus is arranged to move the microplate lid and/or the microplate support is arranged to move the microplate in one respective, in an at least approximately vertical direction for moving the microplate lid away from the microplate. The lid holding apparatus is arranged inside the housing as a magnetic lifter and comprises a non-array arrangement of at least one permanent magnet, or at least three electromagnets, or at least one switchable permanent magnet. Each microplate lid to be moved away from the microplate comprises magnetizable material.

Abstract: Microplate reader has measuring space, action source, measuring device for biological structure signals of microplate wells, transport support for positioning wells in relation to an optical axis of the device and controller for the action source, the measuring device and the transport support. An incubation apparatus with a frame accommodates a microplate with wells having bottoms for reducing liquid evaporation. The frame has a first opening surrounded by an inner wall for the microplate and an outer wall parallel to the inner wall and connected thereto by an intermediate bottom so that a channel is formed and the intermediate bottom for accommodating a liquid adjusted to the content of the microplate wells. The incubation apparatus has a support surface with a second opening for a microplate and, as a result, at least a portion of the well bottoms is freely accessible by the second opening.

Abstract: Microplate reader has a housing, at least one optical measuring/detection device, a microplate support, a moving unit and an integrated lid holding apparatus. The lid holding apparatus moves the microplate in one respective, at least approximately vertical direction for moving the microplate lid away from the microplate. The lid holding apparatus is arranged inside the housing as a magnetic lifter and comprises a non-array arrangement of at least one permanent magnet, or at least three electro magnets, or at least one switchable permanent magnet. Each microplate lid to be moved away from the microplate comprises magnetizable material with a physical area. A projected area of the at least one permanent magnet, electro magnet, or switchable permanent magnet is smaller than the physical area of the magnetizable material of the microplate lid.

Abstract: Microplate reader has measuring space, action source, measuring device for biological structure signals of microplate wells, transport support for positioning wells in relation to an optical axis of the device and controller for the action source, the measuring device and the transport support. An incubation apparatus with a frame accommodates a microplate with wells having bottoms for reducing liquid evaporation. The frame has a first opening surrounded by an inner wall for the microplate and an outer wall parallel to the inner wall and connected thereto by an intermediate bottom so that a channel is formed and the intermediate bottom for accommodating a liquid adjusted to the content of the microplate wells. The incubation apparatus has a support surface with a second opening for a microplate and, as a result, at least a portion of the well bottoms is freely accessible by the second opening.

Abstract: The present invention relates to a system and a method for the immunological detection of several substances or a substance having several features in one step, the detection reaction being based on an immunological sandwich type method and being in particular characterized in that it can easily be carry out and is designed as a “one-pot method”, which means that all detection steps are carried out in one reaction batch without any wash steps and with only one addition of reagents.

Abstract: A method of filling a cartridge that includes a reaction chamber, a biochip mounted in the reaction chamber and a compensation chamber connected so as to communicate with the reaction chamber. The method includes placing a filling nozzle, which is connected so as to communicate with the reaction chamber, such that it is facing upwards, filling a liquid biological sample into the filling nozzle, pressing a stopper into the filling nozzle in order to force sample liquid into the reaction chamber, so that the reaction chamber is filled from bottom to top and an air bubble remains in the compensation chamber downstream of the reaction chamber.

Abstract: Microplate reader has a housing, at least one optical measuring/detection device, a microplate support, a moving unit and an integrated lid holding apparatus. The lid holding apparatus moves the microplate in one respective, at least approximately vertical direction for moving the microplate lid away from the microplate. The lid holding apparatus is arranged inside the housing as a magnetic lifter and comprises a non-array arrangement of at least one permanent magnet, or at least three electro magnets, or at least one switchable permanent magnet. Each microplate lid to be moved away from the microplate comprises magnetizable material with a physical area. A projected area of the at least one permanent magnet, electro magnet, or switchable permanent magnet is smaller than the physical area of the magnetizable material of the microplate lid.

Abstract: A microplate reader (1) comprises a housing (3); at least one optical measuring/detection device (2); a microplate support (4); a moving unit (5); and an integrated lid holding apparatus (6). The lid holding apparatus (6) is arranged to move the microplate lid (7) and/or the microplate support (4) is arranged to move the microplate (8) in one respective, at least approximately vertical direction for moving the microplate lid (7) away from the microplate (8). The lid holding apparatus (6) is arranged inside the housing (3) as a magnetic lifter (6?) and comprises a non-array arrangement of at least one permanent magnet (9?), or at least three electro magnets (10?), or at least one switchable permanent magnet (11). Each microplate lid (7) to be moved away from the microplate (8) comprises magnetizable material (12).

Abstract: Microplate reader with optical measuring/detection device has housing, a microplate support and a moving unit. The moving unit moves the microplate support out and into the housing and horizontally within the housing. The reader has an integrated lid holding apparatus within the housing for lifting and placing a microplate lid on the microplate. The lid holding apparatus moves the microplate lid and/or the microplate support for moving the microplate in one respective vertical direction. A method for optically measuring a microplate in such a microplate reader places a covered microplate on the microplate support, retracts it into the housing, lifts the lid from the microplate, measures the microplate with the lifted lid, replaces the lid, and extends the support and the covered microplate out of the housing.

Abstract: Microplate reader with optical measuring/detection device has housing, a microplate support and a moving unit. The moving unit moves the microplate support out and into the housing and horizontally within the housing. The reader has an integrated lid holding apparatus within the housing for lifting and placing a microplate lid on the microplate. The lid holding apparatus moves the microplate lid and/or the microplate support for moving the microplate in one respective vertical direction. A method for optically measuring a microplate in such a microplate reader places a covered microplate on the microplate support, retracts it into the housing, lifts the lid from the microplate, measures the microplate with the lifted lid, replaces the lid, and extends the support and the covered microplate out of the housing.

Abstract: The cartridge according to the invention for analysing biological samples comprises: a reaction chamber and a biochip mounted in the reaction chamber, a filling nozzle connected so as to communicate with the reaction chamber, and a compensation chamber connected so as to communicate with the reaction chamber, wherein the reaction chamber, the compensation chamber and all lines connected thereto form a chamber sealed as far as the filling nozzle, wherein the filling nozzle forms a free passage to the reaction chamber from outside the cartridge, and a stopper is provided which fits positively and tightly in the filling nozzle in such a way that, when pressed in over a certain distance, fluid is displaced from the filling nozzle towards the reaction chamber.

Abstract: The cartridge according to the invention for analysing biological samples comprises: a reaction chamber and a biochip mounted in the reaction chamber, a filling nozzle connected so as to communicate with the reaction chamber, and a compensation chamber connected so as to communicate with the reaction chamber, wherein the reaction chamber, the compensation chamber and all lines connected thereto form a chamber sealed as far as the filling nozzle, wherein the filling nozzle forms a free passage to the reaction chamber from outside the cartridge, and a stopper is provided which fits positively and tightly in the filling nozzle in such a way that, when pressed in over a certain distance, fluid is displaced from the filling nozzle towards the reaction chamber.

Abstract: The cartridge according to the invention for analysing biological samples comprises: a reaction chamber and a biochip mounted in the reaction chamber, a filling nozzle connected so as to communicate with the reaction chamber, and a compensation chamber connected so as to communicate with the reaction chamber, wherein the reaction chamber, the compensation chamber and all lines connected thereto form a chamber sealed as far as the filling nozzle, wherein the filling nozzle forms a free passage to the reaction chamber from outside the cartridge, and a stopper is provided which fits positively and tightly in the filling nozzle in such a way that, when pressed in over a certain distance, fluid is displaced from the filling nozzle towards the reaction chamber.

Abstract: The present invention relates to a system and a method for the immunological detection of several substances or a substance having several features in one step, the detection reaction being based on an immunological sandwich type method and being in particular characterized in that it can easily be carry out and is designed as a “one-pot method”, which means that all detection steps are carried out in one reaction batch without any wash steps and with only one addition of reagents.

Abstract: The invention relates to a device for carrying out tests on and analyzing biological samples with temperature-controlled biological reactions. It comprises: A reaction chamber (5) for receiving a biochip (6). The reaction chamber comprises at least one transparent window (14) so that excitation light from outside can be radiated onto the biochip (6) and fluorescence light from the biochip can be radiated outward towards a measuring device. A membrane which forms at least one wall of the reaction chamber and is formed so as to be elastic so that the window and the biochip can be pressed against each other to displace the sample solution arranged thereinbetween. The device of the invention is distinguished in that the reaction chamber communicates with a compensation chamber.