Patents by Inventor Friedrich Popp
Friedrich Popp has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 10544047Abstract: The rate of rod fallover in the production of polycrystalline silicon by the Siemens process is sharply reduced by cleaning the Siemens reactor base plate by at least a two-step procedure comprising suctioning the base plate in one step, and subsequently cleaning with liquid or solid cleaning medium in a second step, between each phase of rod removal and new support body installation.Type: GrantFiled: August 10, 2015Date of Patent: January 28, 2020Assignee: WACKER CHEMIE AGInventors: Friedrich Popp, Harald Hertlein
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Patent number: 10525426Abstract: A gas distribution system for a polysilicon deposition reactor eliminates or mitigates the problems associated with prior art distribution systems employs at least two segments which are gas-tightly connected to one another by readily detachable fasteners, with at least one gas inlet opening and one gas outlet opening, the gas distributor of the system being mounted by readily detachable fasteners to the polysilicon reactor.Type: GrantFiled: March 19, 2014Date of Patent: January 7, 2020Assignee: Wacker Chemie AGInventors: Friedrich Popp, Christian Kutza, Martin Roeckl, Tobias Weiss
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Patent number: 10150675Abstract: The native oxide layer on silicon support rods in the Siemens polysilicon production process is removed by heating the rods to a temperature of 1100-1200° C. and contacting the rods with hydrogen at a system pressure of 1.1E5 to 6E6 Pa. Oxide is rapidly removed, reducing overall process time and increasing space time yield. The use of hydrogen, optionally purified from a polysilicon deposition and containing only traces of HCl reduces reactor corrosion and loss of silicon from the support rods.Type: GrantFiled: January 22, 2015Date of Patent: December 11, 2018Assignee: WACKER CHEMIE AGInventors: Harald Hertlein, Friedrich Popp
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Patent number: 9962745Abstract: Contamination of surfaces of polysilicon rods removed from a Siemens reactor in a polysilicon production facility is reduced by cleaning the production facility at least every other week with a cleaning liquid containing water, optionally also containing neutral surfactants.Type: GrantFiled: March 20, 2014Date of Patent: May 8, 2018Assignee: WACKER CHEMIE AGInventors: Harald Hertlein, Friedrich Popp
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Publication number: 20170305748Abstract: The rate of rod fallover in the production of polycrystalline silicon by the Siemens process is sharply reduced by cleaning the Siemens reactor base plate by at least a two-step procedure comprising suctioning the base plate in one step, and subsequently cleaning with liquid or solid cleaning medium in a second step, between each phase of rod removal and new support body installation.Type: ApplicationFiled: August 10, 2015Publication date: October 26, 2017Applicant: Wacker Chemie AGInventors: Friedrich POPP, Harald HERTLEIN
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Publication number: 20170001869Abstract: The native oxide layer on silicon support rods in the Siemens polysilicon production process is removed by heating the rods to a temperature of 1100-1200° C. and contacting the rods with hydrogen at a system pressure of 1.1E5 to 6E6 Pa. Oxide is rapidly removed, reducing overall process time and increasing space time yield. The use of hydrogen, optionally purified from a polysilicon deposition and containing only traces of HCl reduces reactor corrosion and loss of silicon from the support rods.Type: ApplicationFiled: January 22, 2015Publication date: January 5, 2017Applicant: Wacker Chemie AGInventors: Harald HERTLEIN, Friedrich POPP
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Publication number: 20160067663Abstract: A gas distribution system for a polysilicon deposition reactor eliminates or mitigates the problems associated with prior art distribution systems employs at least two segments which are gas-tightly connected to one another by readily detachable fasteners, with at least one gas inlet opening and one gas outlet opening, the gas distributor of the system being mounted by readily detachable fasteners to the polysilicon reactor.Type: ApplicationFiled: March 19, 2014Publication date: March 10, 2016Inventors: Friedrich POPP, Christian KUTZA, Martin ROECKL, Tobias WEISS
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Publication number: 20160045940Abstract: Contamination of surfaces of polysilicon rods removed from a Siemens reactor in a polysilicon production facility is reduced by cleaning the production facility at least every other week with a cleaning liquid containing water, optionally also containing neutral surfactants.Type: ApplicationFiled: March 20, 2014Publication date: February 18, 2016Inventors: Harald HERTLEIN, Friedrich POPP
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Patent number: 7348423Abstract: A process is disclosed for the production of an antifusogenic peptide by producing a fusion peptide of a length of about 14 to 70 amino acids in a prokaryotic host cell, comprising the steps, under such conditions that inclusion bodies of said fusion peptide are formed, of: (a) expressing in said host cell a nucleic acid encoding said fusion peptide consisting of a first peptide which is an antifusogenic peptide of a length of about 10 to 50 amino acids and a second peptide of a length of about 4 to 30 amino acids, said first peptide being N-terminally linked to said second peptide; (b) cultivating said host cell to produce said inclusion bodies; and (c) recovering said antifusogenic peptide from said inclusion bodies, wherein said recovered antifusogenic peptide consists of said fusion peptide or a peptide comprising the antifusogenic peptide of about 10 to 50 amino acids and which is a fragment cleaved from said fusion peptide. Inclusion bodies of the peptides are disclosed.Type: GrantFiled: October 20, 2004Date of Patent: March 25, 2008Assignee: Hoffmann-La Roche Inc.Inventors: Eva Hoess, Thomas Meier, Gabriele Pestlin, Friedrich Popp, Klaus Reichert, Rainer Schmuck, Bernd Schneidinger, Christoph Seidel, Wilhelm Tischer
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Patent number: 7034119Abstract: A method for the recombinant production of a polypeptide by expressing a nucleic acid encoding said polypeptide in a microbial host cell, forming in the cytoplasm of said host cell inclusion bodies containing said polypeptide, and isolating, solubilizing and naturing said polypeptide, characterized in that after fermentation the host cell or the host cell content is incubated at a temperature of 40° C. or higher for at least 10 minutes and subsequently insoluble polypeptide is isolated from the host cell, this method providing an improved yield in inclusion bodies containing the desired polypeptide.Type: GrantFiled: June 12, 2004Date of Patent: April 25, 2006Assignee: Hoffmann-La Roche Inc.Inventors: Rainer Gruenbeck, Erhard Kopetzki, Friedrich Popp
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Publication number: 20050058659Abstract: A process is disclosed for the production of an antifusogenic peptide by producing a fusion peptide of a length of about 14 to 70 amino acids in a prokaryotic host cell, comprising the steps, under such conditions that inclusion bodies of said fusion peptide are formed, of: (a) expressing in said host cell a nucleic acid encoding said fusion peptide consisting of a first peptide which is an antifusogenic peptide of a length of about 10 to 50 amino acids and a second peptide of a length of about 4 to 30 amino acids, said first peptide being N-terminally linked to said second peptide; (b) cultivating said host cell to produce said inclusion bodies; and (c) recovering said antifusogenic peptide from said inclusion bodies, wherein said recovered antifusogenic peptide consists of said fusion peptide or a peptide comprising the antifusogenic peptide of about 10 to 50 amino acids and which is a fragment cleaved from said fusion peptide. Inclusion bodies of the peptides are disclosed.Type: ApplicationFiled: October 20, 2004Publication date: March 17, 2005Inventors: Eva Hoess, Thomas Meier, Gabriele Pestlin, Friedrich Popp, Klaus Reichert, Rainer Schmuck, Bernd Schneidinger, Christoph Seidel, Wilhelm Tischer
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Patent number: 6858410Abstract: A process is provided for producing an antifusogenic peptide by producing a fusion peptide of from about 14 amino acids up to 70 amino acids in a prokaryotic host cell under conditions in which inclusion bodies are formed. The antifusogenic peptide recovered from the inclusion bodies is a fragment cleaved from the fusion peptide which comprises an antifusogenic peptide.Type: GrantFiled: May 30, 2002Date of Patent: February 22, 2005Assignee: Hoffmann-La Roche Inc.Inventors: Eva Hoess, Thomas Meier, Gabriele Pestlin, Friedrich Popp, Klaus Reichert, Rainer Schmuck, Bernd Schneidinger, Christoph Seidel, Wilhelm Tischer
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Publication number: 20050003485Abstract: A method for the recombinant production of a polypeptide by expressing a nucleic acid encoding said polypeptide in a microbial host cell, forming in the cytoplasm of said host cell inclusion bodies containing said polypeptide, and isolating, solubilizing and naturing said polypeptide, characterized in that after fermentation the host cell or the host cell content is incubated at a temperature of 40° C. or higher for at least 10 minutes and subsequently insoluble polypeptide is isolated from the host cell, this method providing an improved yield in inclusion bodies containing the desired polypeptide.Type: ApplicationFiled: June 12, 2004Publication date: January 6, 2005Inventors: Rainer Gruenbeck, Erhard Kopetzki, Friedrich Popp
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Publication number: 20030104581Abstract: A process is disclosed for the production of an antifusogenic peptide by producing a fusion peptide of a length of about 14 to 70 amino acids in a prokaryotic host cell, comprising the steps, under such conditions that inclusion bodies of said fusion peptide are formed, of: (a) expressing in said host cell a nucleic acid encoding said fusion peptide consisting of a first peptide which is an antifusogenic peptide of a length of about 10 to 50 amino acids and a second peptide of a length of about 4 to 30 amino acids, said first peptide being N-terminally linked to said second peptide; (b) cultivating said host cell to produce said inclusion bodies; and (c) recovering said antifusogenic peptide from said inclusion bodies, wherein said recovered antifusogenic peptide consists of said fusion peptide or a peptide comprising the antifusogenic peptide of about 10 to 50 amino acids and which is a fragment cleaved from said fusion peptide. Inclusion bodies of the peptides are disclosed.Type: ApplicationFiled: May 30, 2002Publication date: June 5, 2003Inventors: Eva Hoess, Thomas Meier, Gabriele Pestlin, Friedrich Popp, Klaus Reichert, Rainer Schmuck, Bernd Schneidinger, Christoph Seidel, Wilhelm Tischer
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Publication number: 20020015982Abstract: The invention concerns a method of purifying extrachromosomal DNA by passing an extrachromosomal DNA and fluid containing further cell components through a cross-flow centrifuge under given conditions, resulting in separation of the extrachromosomal DNA from the other cell components such that purified extrachromosomal DNA is obtained. The invention further concerns the use of the purified extrachromosomal DNA for cloning, transformation, transfection and microinjection into cells, for use in gene therapy processes, DNA vaccination and/or for polymerase chain reaction (PCR). The invention finally concerns the use of a cross-flow centrifuge for purifying extrachromosomal DNA.Type: ApplicationFiled: July 9, 1999Publication date: February 7, 2002Applicant: Roche Diagnostics GmbHInventors: WOLFGANG KUHNE, FRIEDRICH POPP
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Patent number: 5679571Abstract: A recombinant protein with D-hydantoinase activity which has the amino acid sequence SEQ ID NO 1 is obtainable in large amounts and has an improved temperature stability.Type: GrantFiled: February 16, 1996Date of Patent: October 21, 1997Assignee: Boehringer Mannheim GmbHInventors: Helmut Burtscher, Gunter Lang, Friedrich Popp
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Patent number: 5523224Abstract: A recombinant protein with D-hydantoinase activity which has the amino acid sequence SEQ ID NO 1 is obtainable in large amounts and has an improved temperature stability.Type: GrantFiled: August 12, 1994Date of Patent: June 4, 1996Assignee: Boehringer Mannheim GmbHInventors: Helmut Burtscher, Gunter Lang, Friedrich Popp
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Patent number: 5118603Abstract: A method of inactivating the biological activity of natural or recombinant DNA in a biomass, by adding a percarboxylic acid containing 1 to 3 carbon atoms, one of its salts, an alkali metal peroxide, or an alkali metal peroxomonosulfate and subsequently heating the mixture to 60.degree. to 100.degree. C.Type: GrantFiled: June 1, 1989Date of Patent: June 2, 1992Assignee: Boehringer Mannheim GmbHInventors: Friedrich Popp, Michael J. Comer, Gunther Schumacher, Michael J. Munster, Bodo Seydler