Patents by Inventor Friedrich Reiff

Friedrich Reiff has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 4605794
    Abstract: A modified sorbitol with improved tableting properties, viz, has a melting point of about 96.degree. C., a bulk density of 0.3-0.6 g/ml, a .gamma.-sorbitol content of at least 90%, a purity of at least 98%, a specific surface area of 0.7-1.5 m.sup.2 /g, a bending strength of at least 7 N/mm.sup.2 at a compressive force of at least 10,000 N, and a friability of less than 1% at a compressive force of at least 10,000 N, can be prepared by obtaining a sorbitol solution by hydrogenation of crystallized glucose at a temperature below 170.degree. C., and spray-drying this solution at a temperature of 140.degree. to 170.degree. C. The sorbitol thus obtained has a water content of less than 1%.The sorbitol is useful for the production of compressed formulations.
    Type: Grant
    Filed: January 23, 1985
    Date of Patent: August 12, 1986
    Assignee: Merck Patent Gesellschaft mit beschrankter Haftung
    Inventors: Friedrich Reiff, Hartmut Hartner, Arno Basedow, Hans-Wolfgang Hugenbusch, Peter C. Schmidt, Hans Bardonner
  • Patent number: 4507511
    Abstract: A modified sorbitol with improved tableting properties, viz, has a melting point of about 96.degree. C., a bulk density of 0.3-0.6 g/ml, a .gamma.-sorbitol content of at least 90%, a purity of at least 98%, a specific surface area of 0.7-1.5 m.sup.2 /g, a bending strength of at least 7 N/mm.sup.2 at a compressive force of at least 10,000 N, and a friability of less than 1% at a compressive force of at least 10,000 N, can be prepared by obtaining a sorbitol solution by hydrogenation of crystallized glucose at a temperature below 170.degree. C., and spray-drying this solution at a temperature of 140.degree. to 170.degree. C. The sorbitol thus obtained has a water content of less than 1%.The sorbitol is useful for the production of compressed formulations.
    Type: Grant
    Filed: December 7, 1983
    Date of Patent: March 26, 1985
    Assignee: Merck Patent Gesellschaft Mit Beschrankter Haftung
    Inventors: Friedrich Reiff, Hartmut Hartner, Arno Basedow, Hans-Wolfgang Hugenbusch, Peter C. Schmidt, Hans Bardonner