Patents by Inventor Friedrich VON WINTZINGERODE

Friedrich VON WINTZINGERODE has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Bacterial endotoxin test for the determination of endotoxins
    Patent number: 11360085
    Abstract: Herein is reported a method for determining bacterial endotoxin at low concentrations in a sample of an antibody (that has been produced using bacterial cells) comprising the following steps in the following order: i) adding magnesium ions to the sample, ii) diluting the sample, iii) dialyzing the sample having a pH-value of 5.7-8.0 against an endotoxin-flee aqueous solution, and iv) determining bacterial endotoxin in the sample using a bacterial endotoxin test, particularly the Limulus amoebocyte lysate assay.
    Type: Grant
    Filed: January 28, 2020
    Date of Patent: June 14, 2022
    Assignees: Forschungszentrum Borstel Leibniz Lungenzentrum, Hoffmann-La Roche Inc.
    Inventors: Christian Alexander, Sven Deutschmann, Pierre Lang, Friedrich Von Wintzingerode, Ulrich Zaehringer
  • BACTERIAL ENDOTOXIN TEST FOR THE DETERMINATION OF ENDOTOXINS
    Publication number: 20200240988
    Abstract: Herein is reported a method for determining bacterial endotoxin at low concentrations in a sample of an antibody (that has been produced using bacterial cells) comprising the following steps in the following order: i) adding magnesium ions to the sample, ii) diluting the sample, iii) dialyzing the sample having a pH-value of 5.7-8.0 against an endotoxin-flee aqueous solution, and iv) determining bacterial endotoxin in the sample using a bacterial endotoxin test, particularly the limulus amoebocyte lysate assay.
    Type: Application
    Filed: January 28, 2020
    Publication date: July 30, 2020
    Inventors: Christian ALEXANDER, Sven DEUTSCHMANN, Pierre LANG, Friedrich VON WINTZINGERODE, Ulrich ZAEHRINGER
  • Bacterial endotoxin test for the determination of endotoxins
    Patent number: 10585097
    Abstract: Herein is reported a method for determining bacterial endotoxin at low concentrations in a sample of an antibody (that has been produced using bacterial cells) comprising the following steps in the following order: i) adding magnesium ions to the sample, ii) diluting the sample, iii) dialyzing the sample having a pH-value of 5.7-8.0 against an endotoxin-free aqueous solution, and iv) determining bacterial endotoxin in the sample using a bacterial endotoxin test, particularly the limulus amoebocyte lysate assay.
    Type: Grant
    Filed: July 27, 2016
    Date of Patent: March 10, 2020
    Assignees: Forschungszentrum Borstel Leibniz Lungerzentrum, Hoffmann-La Roche Inc.
    Inventors: Christian Alexander, Sven Deutschmann, Pierre Lang, Friedrich Von Wintzingerode, Ulrich Zaehringer
  • IMPROVED BACTERIAL ENDOTOXIN TEST FOR THE DETERMINATION OF ENDOTOXINS
    Publication number: 20180188249
    Abstract: Herein is reported a method for determining bacterial endotoxin at low concentrations in a sample of an antibody (that has been produced using bacterial cells) comprising the following steps in the following order: i) adding magnesium ions to the sample, ii) diluting the sample, iii) dialyzing the sample having a pH-value of 5.7-8.0 against an endotoxin-free aqueous solution, and iv) determining bacterial endotoxin in the sample using a bacterial endotoxin test, particularly the limulus amoebocyte lysate as say.
    Type: Application
    Filed: July 27, 2016
    Publication date: July 5, 2018
    Inventors: Christian ALEXANDER, Sven DEUTSCHMANN, Pierre LANG, Friedrich VON WINTZINGERODE, Ulrich ZAEHRINGER