Abstract: An apparatus for measuring ionizing radiation includes a detector having a cathode, an anode, a counting gas between the cathode and the anode for generating gas ionization by ionizing radiation, a voltage source for applying a voltage between the cathode and the anode, and a current measuring device for measuring a detector current between the cathode and the anode. The detector current is generated in the counting gas by the ionizing radiation. The apparatus further includes a setting device, wherein the setting device is configured for independently setting the apparatus into different operating modes depending on the measured detector current, and/or wherein the setting device is configured for independently setting the apparatus into different measurement ranges depending on the measured detector current.

Abstract: A radiometric measuring device has a counting tube having an anode and a cathode, and is configured to determine a measurement variable depending on properties of ionizing radiation that impinges on the counting tube. In a first measurement mode, a constant first voltage is set between anode and cathode such that the counting tube operates as a proportional counting tube, and the measurement variable is determined depending on a current flowing between anode and cathode. In a second measurement mode, the current flowing between anode and cathode is controlled to a current setpoint value, wherein the voltage between anode and cathode serves as a manipulated variable of the current control, and the measurement variable is determined depending on the voltage between anode and cathode.

Abstract: A device for a multimodal imaging examination of an object, in particular for a multimodal imaging examination of a living object, includes an object carrier for accommodating at least one object to be examined, an x-ray radiation source for emitting x-ray radiation, a first partial system for generating a first image of the object in a first image recording mode and a second partial system for generating a second image of the object in a second image recording mode. The first partial system has a direct digital x-ray detector which is configured to convert x-ray radiation modified by the object into a digital image of the object. The second partial system has a camera system which is configured to convert radiation in the visible wavelength range or UV wavelength range emanating from an object into a digital image of the object.

Abstract: Described is a luminometer or fluorometer having an optical axis which extends essentially perpendicular to the measuring sample. The detector for the luminometer or the fluorometer is arranged either directly or via a deflection means in the optical axis. An injection device (20) with an injection channel is provided for feeding in the reagents, wherein the injection channel consists of a first section and a second section, arranged at an angle relative to the first section, and is provided with a discharge opening (24c) that points in the direction of the measuring sample.

Abstract: An apparatus for selected measurement of at least one of luminescent and fluorescent radiation from at least one sample well, the apparatus comprising: means defining an excitation light path for fluorescence measurements; at least one light source in the excitation path; means defining an emission light path; and at least one detector with a wavelength selector in the emission light path, wherein: the apparatus further comprises at least one first reflector element that encompasses a reflection chamber and projects at least a portion of the light emitted from the at least one sample well directionally onto the wavelength selector; the emission light path extends between the at least one sample well and the wavelength selector through the at least one first reflector element; and the excitation light path extends into the reflection chamber and extends to a point above the at least one sample well.

Abstract: A method for detecting ionizing radiation with the aid of a scintillation counter and a photomultiplier using an inorganic solid-matter scintillator that incorporates at least one decay time component greater than 100 ns and measures the photons emitted by the scintillator with a fast single-photon counter. The single-photon counter is composed of a fast photomultiplier with high internal amplification, a stabilized high-voltage supply and a fast amplifier/discriminator with standard pulse output. With this arrangement, the measurement of all types of radiation, like alpha, beta, gamma and X radiation, can be performed, with low manufacturing costs for the detector, a high degree of sensitivity especially with regard to low beta energies, only small sensitivity changes over a large temperature range of ?20 to +50 degrees C., and good long-term stability.

Abstract: A method for detecting ionizing radiation with the aid of a scintillation counter and a photomultiplier using an inorganic solid-matter scintillator that incorporates at least one decay time component greater than 100 ns and measures the photons emitted by the scintillator with a fast single-photon counter. The single-photon counter is composed of a fast photomultiplier with high internal amplification, a stabilized high-voltage supply and a fast amplifier/discriminator with standard pulse output. With this arrangement, the measurement of all types of radiation, like alpha, beta, gamma and X radiation, can be performed, with low manufacturing costs for the detector, a high degree of sensitivity especially with regard to low beta energies, only small sensitivity changes over a large temperature range of ?20 to +50 degrees C., and good long-term stability.

Abstract: A rapid detection of ATP using dried luciferase/luciferin reagent. A liquid that may include an extraction reagent is applied to the testing surface, such as a counter top. A sampling device having a handle and an absorbent tip is wiped across the testing surface. The absorbent tip absorbs the sample. The sample is then placed in a counting tube. Luciferase/luciferin reagent is immobilized on the absorbent tip of the sampling device or in the bottom of a counting tube. In either case, the liquid rehydrates the luciferase/luciferin reagent allowing ATP present in the sample to react with the luciferase. Light produced by the reaction is measured with a luminometer.

Abstract: A rapid detection of ATP using dried luciferase/luciferin reagent. A liquid that may include an extraction reagent is applied to the testing surface, such as a counter top. A sampling device having a handle and an absorbent tip is wiped across the testing surface. The absorbent tip absorbs the sample. The sample is then placed in a counting tube. Luciferase/luciferin reagent is immobilized on the absorbent tip of the sampling device or in the bottom of a counting tube. In either case, the liquid rehydrates the luciferase/luciferin reagent allowing ATP present in the sample to react with the luciferase. Light produced by the reaction is measured with a luminometer.

Abstract: A method for discrimination and simultaneous or separate measurement of single or multiple electronic events in an opto-electronic detector, such as a photo-multiplier, wherein information for the discrimination of these events is obtained from the signal progression occurring at the detector output within a predeterminable time window. According to this method, a characteristic parameter (T.sub.M ; t.sub.b -t.sub.a) is obtained for the temporal "center of gravity" of the progression of the signal itself or its integral over the time window (T.sub.F), the value of which is compared with a reference value (T.sub.S ; C.sub.1) which this parameter assumes during a single photo-electron event.

Abstract: A method and device for effecting a location-sensitive measurement of a flat sample of radiation emitting material having a plurality of partial areas, in which a screen plate having radiation passage openings is disposed between a detector and the sample; radiation emanating from a group of the partial areas is detected in accordance with the shape of the screen plate openings; information based on the detected radiation is stored; and then a relative displacement is effected between the sample and the detector and detecting and storing are repeated for another group of partial areas, so that the total measurement is composed of a plurality of such successively performed partial measurements which provide a measurement of the total distribution of radiation emitted by the sample.

Abstract: A counting tube for detecting radioactive radiation exclusively uses cathode pads for signal detection, which are disposed electrically insulated on the interior of an inner wall of the counting tube housing opposite the sample. A discrete electronic evaluation element is preferably allocated to each cathode element, which makes possible parallel evaluation of the counting tube signal. The cathode pads are in particular laminated in the form of a metal-coated conductive surface on a support plate made of an insulating material. The field of application of such counting tubes with the exclusive use of cathode pads is in particular in connection with multiple counting tubes where the partial areas of a total area to be measured are intended to be individually detected and evaluated.

Abstract: A radiation measuring apparatus for performing measurements on samples contained in a plurality of sample containers disposed in the form of a matrix on a holder plate, the apparatus including a radiation detector having an entrance window, displacement devices for aligning successive sample containers with the entrance window of the radiation detector for automatic measurement of samples in the sample containers, the radiation detector and the sample containers being movable relative to one another in such a way that the sample container being measured and the entrance window of the detector are disposed coaxially with each other.

Abstract: A system for a plurality of specimen containers for performing assays, such as chemo- or bioluminescence measurements, includes a support element used for transporting the specimen containers through a measuring instrument, and a holder in which a plurality of specimen containers are received and which, for performing the measurement, can be mounted on the support element. The holder is a disposable component, so that once the measurement has been performed it can be discarded along with the specimen containers. For receiving multiple holders outside the measuring instrument, a stand is provided. Both on the holder and on the stand and support element, special provisions are made for positioning of the specimen containers both in the stand and in the support element in a way that both assures satisfactory measurement and precludes any mistake in the order of the specimen containers during the measurement or during the preparatory steps in the process.

Abstract: A specimen rack for specimen containers such as test tubes composed of M structurally identical holders for linearly receiving N specimen containers at a time as well as a stand for receiving the M holders, which stand has vertical side parts, so that a plurality of holders can be mounted on the stand parallel to one another and affixed there by means of a detent connection. With this modularly designed specimen rack, the stand enables secure holding of multiple containers, while contrarily the holders, in which the specimen containers can remain during all the stages of the procedure, may be an inexpensive disposable plastic part the purpose of which is merely the linear, spatial association of a number of specimen containers, and which after the measurement is ended can optionally be discarded along with the specimen containers. Because of the minimal design of such a holder, any disposal problems are also slight.

Abstract: A specimen rack composed of a block having a matrix-like arrangement of M.times.N through chambers, into which M.times.N cuvettes can be inserted, individually or in the form of strip-racks. Separate connecting strips may be provided to form the strip-racks, and these strips, like the block, are of radiopaque material so that each cuvette, except for a region defined by the lower opening cross section of the through chambers and their upper filling opening, is continuously opaquely shielded from scattering radiation from adjacent cuvettes. Annular shoulders, serving as rests, are dimensioned and disposed in the through chambers such that the vertical position and thus the assay position of the cuvettes in the through chambers can be fixed in defined fashion. Thus the measurement sensitivity on the one hand and possible crosstalk phenomena in the vicinity of the measurement openings on the other can be minimized or optimally adapted to one another.

Abstract: A measuring instrument for bioluminescence and chemiluminescence has coupled holders that can slide on a horizontal locating surface with specimen pans, which are fed successively to a light entry port (point of measurement) which is shielded outwardly in light-tight fashion. The holders are fitted with a side window and the point of measurement is placed at the level of these windows opposite thereto.Among other advantages, the specimen pans need no longer be removed from their holders in order to carry out the measurement at the point of measurement, but can remain therein. The mechanical driving and sliding mechanisms for this vertical lift needed heretofore can thus be dispensed with.

Abstract: A method for measuring the radioactivity in eluates from liquid chromatography columns in which a portion of the eluate stream is split off and mixed with a scintillation fluid in a timed sequence wherein the volume of eluate and the volume of scintillation cocktail are quantitatively and reproduceably controlled. An apparatus for the practice of this method comprising a two-position valve on the affluent stream, a two-position valve on a pumped closed loop of scintillation cocktail a means for simultaneously setting the position of each valve and a mixing chamber discharging to a scintillation counter is also described. By the practice of this method, it is possible to determine the radioactivity of the eluate as well as to preserve a sample of the eluate for further analysis.

Abstract: Process for carrying out an analytical determination of the presence of a substance by means of chemiluminescence, comprising employing fluorescein isothiocyanate (FITC) as a labelling agent, triggering a chemiluminescence reaction by adding an aqueous solution of sodium hypochlorite, and measuring the emission of light.

Abstract: A method for determining the quench corrected counting yield of samples which emit ionizing radiation that is subject to quenching in a liquid scintillation counter. The output signal of a photoelectric transducer device is used to measure the counting rates of the sample spectrum in different given pulse height ranges. A value characteristic for the quenching is derived from the measurement to determine a quench corrected counting a yield.