Abstract: The invention relates to a process and a device for manufacturing segmented pressure-sensitive adhesive layers and applying the same to a substrate, involving the use of a reaction medium containing radiation-inducible polymers and/or prepolymers of olefinically unsaturated compounds and the addition of a photoinitiator.

Abstract: The invention relates to reservoirs with a delivery surface for the controlled delivery of active substances decreasing over the time of use to solid, liquid or gaseous acceptors and whereby at least at one point of the reservoir a cross-sectional surface of the reservoir is parallel to the delivery surface and smaller in area than the delivery surface. The invention also relates to an apparatus for the controlled delivery of active substances decreasing over the time of use, which has at least one reservoir. At least one active substance to be delivered is active in the technical, human and veterinary medical, cosmetic and pest control sectors.

Abstract: The invention relates to a pharmaceutic product as well as to a process for its production for a transdermal application in the prophylaxis and treatment of vasodilations, said pharmaceutic product comprising at least one skin-compatible auxiliary agent and portions of an active substance, characterized in that said pharmaceutic product contains as active substance pentetrazole.

Abstract: A transdermal therapeutic system (TTS) comprises compounds releasing carbon monoxide in organisms to increase the CO-concentration in the organism.

Abstract: A transdermal therapeutic system exhibiting layered structure consists of a backing layer which is impermeable to active substances, a matrix having water-insoluble basic material and islands (inclusions) divided therein, and a layer controlling the access of cutaneous liquid by means of which the matrix is activatable. Process for the production are described.

Abstract: A flexible, hydrophilic, water-swellable but insoluble gel film which consists of(a) 0.5 to 30%-wt of at least one water-soluble polymer being anion-active at neutral pH(b) 0.5 to 50%-wt of at least one water-soluble polymer being cation-active at neutral pH(c) 0.1 to 20%-wt of at least one moisturizer(d) 0.1 to 70%-wt of water(e) 0 to 75%-wt of water-soluble or water-dispersible auxiliaries(f) 0 to 50%-wt of active substancea process for its production and the use of this film for the production of a device creating interactions between the gel film and a solid, liquid, or gaseous substrate.

Abstract: A transdermal therapeutic system exhibiting layered structure consists of a backing layer which is impermeable to active substances, a matrix having water-insoluble basic material and islands (inclusions) divided therein, and a layer controlling the access of cutaneous liquid by means of which the matrix is activatable. Process for the production are described.

Abstract: A transdermal therapeutic system is disclosed which comprises an optional flexible backing layer, one or more drug reservoir(s), one or more adhesive layer(s) and optionally a detachable protective layer for the skin contact surface of the flat therapeutical system. The skin contact area of the therapeutical system is a skin contact layer which has one or more non-adhesive drug-releasing section(s) and one or more skin-adhesion section(s), which optionally contain a further drug. A process is disclosed for the production of the system, as well as the use thereof for local or systemic, transdermal administration of drugs in human or veterinary medicine or in cosmetics.

Abstract: A dispensing device for a radionuclide generator includes an eluant container, a receptacle for receiving the container, the receptacle being in sliding engagement with a support, a hollow needle which pierces the elastic stopper of the container so that the tip of the needle penetrates into the container, and a fixing device for holding the needle at a distance from its tip. The volume dispensed from the container is controlled by shifting the receptacle up or down within the support along the longitudinal axis of the needle.

Abstract: Increasing the oxidation state of plutonium to Pu (VI) by circulating a starting solution of U.sup.6 and Pu.sup.4 -nitrates and HNO.sub.3 through an electrolysis cell at an electrode voltage of about 3 volts.

Abstract: In apparatus for separating ions in a solution by countercurrent electrolysis, a generally cylindrical column is constituted by axially juxtaposed annular segments which define respective chambers separated by liquid-permeable partitions. The two axially terminal chambers contain electrodes. Radial bores in the segments permit introduction and discharge of the solution to be tested, of an electrolyte flowing countercurrent to the solution, and of a cooling liquid passing through a cooling coil in each chamber. A shaft axially extending through the column carries agitating blades in each chamber and is magnetically rotated.