Abstract: The present invention provides antibodies useful as therapeutics for treating and/or preventing diseases associated with cells expressing CLD18, including tumor-related diseases such as gastric cancer, esophageal cancer, pancreatic cancer, lung cancer, ovarian cancer, colon cancer, hepatic cancer, head-neck cancer, and cancer of the gallbladder.

Abstract: The quick action slide valve comprises a valve casing and a sliding plate sliding in an annular groove in the product pipe. The annular groove in the product pipe is closed by a collar and at the side opposite to the sliding plate braking means are provided to stop the plate inelastically when the slide valve is closed. The sliding plate is provided on one surface with wedges which slide upon bolts in the annular groove when the valve is closed. Guide means rigidly connected with the valve casing protrude into a recess of the sliding plate when the slide valve is open. In the said recess at the end of the guide means a propellant charge is mounted which is ignited by ignition means running to the outside through the guide means when a certain pressure is exceeded.