Patents by Inventor Fritz Theil

Fritz Theil has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Substituted azaspiro(4.5)decane derivatives
    Patent number: 10214520
    Abstract: The invention relates to substituted spirocyclic cyclohexane derivatives which have an affinity for the ? opioid receptor and/or the ORL1 receptor, processes for the preparation thereof, medicaments containing these compounds and the use of these compounds for the preparation of medicaments.
    Type: Grant
    Filed: July 14, 2015
    Date of Patent: February 26, 2019
    Assignee: GRUENENTHAL GMBH
    Inventors: Anita Wegert, Sven Kuehnert, Rene Michael Koenigs, Bert Nolte, Klaus Linz, Stephanie Harlfinger, Babette-Yvonne Koegel, Paul Ratcliffe, Fritz Theil, Olga Groeger, Birgit Braun
  • Substituted azaspiro(4.5)decane derivatives
    Patent number: 10202345
    Abstract: The invention relates to substituted spirocyclic cyclohexane derivatives which have an affinity for the ? opioid receptor and the ORL1 receptor, processes for the preparation thereof, medicaments containing these compounds and the use of these compounds for the preparation of medicaments.
    Type: Grant
    Filed: July 15, 2015
    Date of Patent: February 12, 2019
    Assignee: GRUENENTHAL GMBH
    Inventors: Anita Wegert, Bert Nolte, Klaus Linz, Stephanie Harlfinger, Babette-Yvonne Koegel, Paul Ratcliffe, Fritz Theil, Olga Groeger, Birgit Braun
  • Substituted Azaspiro(4.5)Decane Derivatives
    Publication number: 20170210734
    Abstract: The invention relates to substituted spirocyclic cyclohexane derivatives which have an affinity for the ? opioid receptor and/or the ORL1 receptor, processes for the preparation thereof, medicaments containing these compounds and the use of these compounds for the preparation of medicaments.
    Type: Application
    Filed: July 14, 2015
    Publication date: July 27, 2017
    Applicant: Gruenenthal GmbH
    Inventors: Anita WEGERT, Sven KUEHNERT, Rene Michael KOENIGS, Bert NOLTE, Klaus LINZ, Stephanie HARLFINGER, Babette-Yvonne KOEGEL, Paul RATCLIFFE, Fritz THEIL, Olga GROEGER, Birgit BRAUN
  • Substituted Azaspiro(4.5)Decane Derivatives
    Publication number: 20160016903
    Abstract: The invention relates to substituted spirocyclic cyclohexane derivatives which have an affinity for the ? opioid receptor and the ORL1 receptor, processes for the preparation thereof, medicaments containing these compounds and the use of these compounds for the preparation of medicaments.
    Type: Application
    Filed: July 15, 2015
    Publication date: January 21, 2016
    Inventors: Anita WEGERT, Bert NOLTE, Klaus LINZ, Stephanie HARLFINGER, Babette-Yvonne KOEGEL, Paul RATCLIFFE, Fritz THEIL, Olga GROEGER, Birgit BRAUN
  • Substituted cyclohexyldiamines
    Patent number: 8357705
    Abstract: The invention relates to compounds that have an affinity to the ?-opioid receptor and the ORL 1-receptor, methods for their production, medications containing these compounds and the use of these compounds for the treatment of pain or other conditions.
    Type: Grant
    Filed: March 25, 2009
    Date of Patent: January 22, 2013
    Assignee: Gruenenthal GmbH
    Inventors: Saskia Zemolka, Bert Nolte, Klaus Linz, Derek John Saunders, Wolfgang Schröder, Werner Englberger, Fritz Theil, Hans Schick, Jens Kaufmann, Julian Gebauer, Helmut Sonnenschein
  • Hydroxymethylcyclohexylamines
    Patent number: 8288406
    Abstract: The invention relates to compounds which have an affinity for the ? opioid receptor and the ORL1 receptor, processes for the preparation thereof, medicaments containing these compounds and the use of these compounds for the preparation of medicaments.
    Type: Grant
    Filed: September 22, 2010
    Date of Patent: October 16, 2012
    Assignee: Gruenenthal GmbH
    Inventors: Sven Frormann, Saskia Zemolka, Klaus Linz, Werner Englberger, Fritz Theil
  • Spiro(5.5)undecane derivatives
    Patent number: 8288430
    Abstract: The invention relates to compounds that have an affinity to the ?-opioid receptor and the ORL 1-receptor, methods for their production, medications containing these compounds and the use of these compounds for the treatment of pain and other conditions.
    Type: Grant
    Filed: March 25, 2009
    Date of Patent: October 16, 2012
    Assignee: Grunenthal GmbH
    Inventors: Saskia Zemolka, Stefan Schunk, Klaus Linz, Wolfgang Schröder, Werner Englberger, Fritz Theil, Birgit Roloff
  • Salts of substituted allophanates and their use in drugs
    Patent number: 8173700
    Abstract: The present invention relates to salts of substituted allophanates, methods for their production, medicaments containing said compounds and the use of said compound for the production of medicaments.
    Type: Grant
    Filed: May 17, 2006
    Date of Patent: May 8, 2012
    Assignee: Gruenenthal GmbH
    Inventors: Robert Frank, Ruth Jostock, Hans Schick, Fritz Theil, Olga Groeger, Rene Kudick, Helmut Sonnenschein, Birgitta Henkel
  • Substituted sulfonamide compounds
    Patent number: 8119633
    Abstract: Substituted sulfonamide compounds corresponding to formula I pharmaceutical compositions comprising them, a process for preparing them, and the use of such compounds to treat or inhibit pain and other disorders or disease states.
    Type: Grant
    Filed: April 30, 2008
    Date of Patent: February 21, 2012
    Assignee: Gruenenthal GmbH
    Inventors: Beatrix Merla, Stefan Oberboersch, Melanie Reich, Bernd Sundermann, Werner Englberger, Timo Struenker, Ruth Jostock, Sabine Hees, Edward Bijsterveld, Fritz Theil, Heinz Graubaum
  • Substituted amide compounds
    Patent number: 8106055
    Abstract: Substituted amide compounds corresponding to formula I: processes for preparing them, pharmaceutical compositions containing these compounds, and the use of substituted amide derivatives for the preparation of medicaments for the treatment of pain and various other conditions.
    Type: Grant
    Filed: April 30, 2008
    Date of Patent: January 31, 2012
    Assignee: Gruenenthal GmbH
    Inventors: Stefan Oberboersch, Melanie Reich, Bernd Sundermann, Utz-Peter Jagusch, Beatrix Merla, Stefan Schunk, Werner Englberger, Timo Struenker, Hagen-Heinrich Hennies, Edward Bijsterveld, Fritz Theil, Heinz Graubaum
  • Hydroxymethylcyclohexylamines
    Publication number: 20110059999
    Abstract: The invention relates to compounds which have an affinity for the ? opioid receptor and the ORL1 receptor, processes for the preparation thereof, medicaments containing these compounds and the use of these compounds for the preparation of medicaments.
    Type: Application
    Filed: September 22, 2010
    Publication date: March 10, 2011
    Applicant: GRÜNENTHAL GMBH
    Inventors: Sven Frormann, Saskia Zemolka, Klaus Linz, Werner Englberger, Fritz Theil
  • Substituted Sulfonamide Compounds
    Publication number: 20090253669
    Abstract: Substituted sulfonamide compounds corresponding to the formula I: processes for the preparation thereof, pharmaceutical composition containing these compounds and the use of substituted sulfonamide compounds for the preparation of pharmaceutical compositions.
    Type: Application
    Filed: March 16, 2009
    Publication date: October 8, 2009
    Applicant: GRUENENTHAL GmbH
    Inventors: Stefan OBERBOERSCH, Melanie REICH, Bernd SUNDERMANN, Werner ENGLBERGER, Sabine HEES, Ruth JOSTOCK, Stefan SCHUNK, Edward BIJSTERVELD, Fritz THEIL
  • SPIRO(5.5)UNDECANE DERIVATIVES
    Publication number: 20090247505
    Abstract: The invention relates to compounds that have an affinity to the ?-opioid receptor and the ORL 1-receptor, methods for their production, medications containing these compounds and the use of these compounds for the treatment of pain and other conditions.
    Type: Application
    Filed: March 25, 2009
    Publication date: October 1, 2009
    Applicant: Grunenthal GMBH
    Inventors: Saskia ZEMOLKA, Stefan SCHUNK, Klaus LINZ, Wolfgang SCHRODER, Werner ENGLBERGER, Fritz THEIL, Birgit ROLOFF
  • SUBSTITUTED CYCLOHEXYLDIAMINES
    Publication number: 20090247591
    Abstract: The invention relates to compounds that have an affinity to the ?-opioid receptor and the ORL 1-receptor, methods for their production, medications containing these compounds and the use of these compounds for the treatment of pain or other conditions.
    Type: Application
    Filed: March 25, 2009
    Publication date: October 1, 2009
    Applicant: Grunenthal GmbH
    Inventors: Saskia Zemolka, Bert Nolte, Klaus Linz, Derek John Saunders, Wolfgang Schroder, Wemer Englberger, Fritz Theil, Hans Schick, Jens Kaufmann, Julian Gebauer, Helmut Sonnenschein
  • Salts of Substituted Allophanates and Their Use in Drugs
    Publication number: 20090062383
    Abstract: The present invention relates to salts of substituted allophanates, methods for their production, medicaments containing said compounds and the use of said compound for the production of medicaments.
    Type: Application
    Filed: May 17, 2006
    Publication date: March 5, 2009
    Applicant: Gruenenthal GmbH
    Inventors: Robert Frank, Ruth Jostock, Hans Schick, Fritz Theil, Olga Groeger, Rene Kudick, Helmut Sonnenschein, Birgitta Henkel
  • Substituted Sulfonamide Compounds
    Publication number: 20080312231
    Abstract: Substituted sulfonamide compounds corresponding to formula I pharmaceutical compositions comprising them, a process for preparing them, and the use of such compounds to treat or inhibit pain and other disorders or disease states.
    Type: Application
    Filed: April 30, 2008
    Publication date: December 18, 2008
    Applicant: Gruenenthal GmbH
    Inventors: Beatrix MERLA, Stefan Oberboersch, Melanie Reich, Bernd Sundermann, Werner Englberger, Timo Struenker, Ruth Jostock, Sabine Hees, Edward Bijsterveld, Fritz Theil, Heinz Graubaum
  • Substituted Amide Compounds
    Publication number: 20080306084
    Abstract: Substituted amide compounds corresponding to formula I: processes for preparing them, pharmaceutical compositions containing these compounds, and the use of substituted amide derivatives for the preparation of medicaments for the treatment of pain and various other conditions.
    Type: Application
    Filed: April 30, 2008
    Publication date: December 11, 2008
    Applicant: Gruenenthal GmbH
    Inventors: Stefan Oberboersch, Melanie Reich, Bernd Sundermann, Utz-Peter Jagusch, Beatrix Merla, Stefan Schunk, Werner Englberger, Timo Struenker, Hagen-Heinrich Hennies, Edward Bijsterveld, Fritz Theil, Heinz Graubaum
  • Pyrrolidine(thi)ones Substituted by Heterocyclic Substituents in The 3-Position
    Publication number: 20080293749
    Abstract: Pyrrolidine(thi)one compounds substituted by heterocyclic substituents in the 3-position, their preparation and use in pharmaceutical compositions, in particular as immunomodulators for treatment and/or inhibition of inflammatory and autoimmune diseases and haematological-oncological diseases.
    Type: Application
    Filed: June 2, 2008
    Publication date: November 27, 2008
    Applicant: Gruenenthal GmbH
    Inventors: Sven FRORMANN, Stefanie FROSCH, Carsten GRIEBEL, Derek SAUNDERS, Fritz THEIL, Heinz GRAUBAUM
  • Substituted Spiro Compounds and their Use for Producing Drugs
    Publication number: 20080214807
    Abstract: The present invention relates to substituted spiro compounds, to processes for preparing them, to medicaments comprising these compounds and to the use of these compounds for producing medicaments.
    Type: Application
    Filed: May 17, 2006
    Publication date: September 4, 2008
    Applicant: Gruenenthal GmbH
    Inventors: Hans Schick, Robert Frank, Melanie Reich, Ruth Jostock, Gregor Bahrenberg, Fritz Theil, Birgitta Henkel
  • Process for producing piperidine-2,6 diones heterocyclically substituted in the 3-position
    Publication number: 20070155967
    Abstract: An improved process for producing piperidine-2,6-diones heterocyclically substituted at the 3-position in a minimal number of reaction stages by reacting a 2-aminobenzylamine with a 3-bromoglutarimide to obtain an amine of formula (IV): and thereafter reacting the obtained amine of formula (IV) with a suitable further reactant.
    Type: Application
    Filed: November 28, 2006
    Publication date: July 5, 2007
    Applicant: Gruenenthal Gmbh
    Inventors: Oswald Zimmer, Fritz Theil, Olga Groeger