Patents by Inventor Fu Fan

Fu Fan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11384343
    Abstract: The present invention relates to non-naturally occurring polypeptides useful for preparing armodafinil, polynucleotides encoding the polypeptides, and methods of using the polypeptides. The non-naturally occurring polypeptides of the present invention are effective in carrying out biocatalytic conversion of the (i) 2-(benzhydrylsulfinyl)acetamide to (?)-2-[(R)-(diphenylmethyl)sulfinyl]acetamide (armodafinil), or (ii) benzhydryl-thioacetic acid to (R)-2-(benzhydrylsulfinyl)acetic acid, which is a pivotal intermediate in the synthesis of armodafinil, in enantiomeric excess.
    Type: Grant
    Filed: February 24, 2021
    Date of Patent: July 12, 2022
    Assignee: Codexis, Inc.
    Inventors: Ee Lui Ang, Oscar Alvizo, Behnaz Behrouzian, Michael D. Clay, Steven J. Collier, Ellen D. Eberhard, Fu Fan, Shiwei Song, Derek J. Smith, Magnus Widegren, Robert Wilson, Junye Xu, Jun Zhu
  • Patent number: 11355312
    Abstract: The present invention provides a driving system comprising two actuators for moving a stage through two elastic connectors; and a general apparatus/device comprising such a driving system, such as a machine tool, an analytical instrument, an optical microscope, and an apparatus of charged-particle beam such as electron microscope and an electron beam lithographical apparatus. When used in an electron microscope, the stage can be used as a specimen stage or a plate having apertures for electron beam to pass through. The novel stage driving system exhibits numerous technical merits such as simpler structure, better manufacturability, improved cost-effectiveness, and higher reliability, among others.
    Type: Grant
    Filed: August 1, 2021
    Date of Patent: June 7, 2022
    Assignee: BORRIES PTE. LTD.
    Inventors: Zhongwei Chen, Xiaoming Chen, Daniel Tang, Liang-Fu Fan
  • Patent number: 11328898
    Abstract: The present invention provides a digital high-resolution detector for detecting X-ray, UV light or charged particles. In various embodiments, the digital detector comprises an array of CMOS or CCD pixels and a layer of conversion material on top of the array designed for converting incident X-ray, UV light or charged particles into photons for CMOS or CCD sensors to capture. The thin and high-resolution detector of the invention is particularly useful for monitoring and aligning beams in, and optimizing system performance of, an apparatus of charged-particle beam e.g. an electron microscope.
    Type: Grant
    Filed: July 8, 2021
    Date of Patent: May 10, 2022
    Assignee: BORRIES PTE. LTD.
    Inventors: Zhongwei Chen, Xiaoming Chen, Daniel Tang, Liang-Fu Fan
  • Publication number: 20220115204
    Abstract: The present invention provides an apparatus of charged-particle beam e.g. an electron microscope comprising an in-column plasma generator for selectively cleaning BSE detector and BF/DF detector. In various embodiments, the plasma generator is located between a lower pole piece of objective lens and the BF/DF detectors, but outside trajectory area of the charged-particles from the sample stage to the BF/DF detector. Cleaning decomposed biological samples or contaminants on the surface of the detectors frequently and selectively with in-situ generated plasma can prevent the detectors from performance deterioration such as losing resolution and contrast in imaging at high levels of magnification.
    Type: Application
    Filed: December 17, 2021
    Publication date: April 14, 2022
    Inventors: Zhongwei Chen, Xiaoming Chen, Daniel Tang, Liang-Fu Fan
  • Publication number: 20220108443
    Abstract: A rapid and automatic virus imaging and analysis system includes (i) electron optical sub-systems (EOSs), each of which has a large field of view (FOV) and is capable of instant magnification switching for rapidly scanning a virus sample; (ii) sample management sub-systems (SMSs), each of which automatically loads virus samples into one of the EOSs for virus sample scanning and then unloads the virus samples from the EOS after the virus sample scanning is completed; (iii) virus detection and classification sub-systems (VDCSs), each of which automatically detects and classifies a virus based on images from the EOS virus sample scanning; and (iv) a cloud-based collaboration sub-system for analyzing the virus sample scanning images, storing images from the EOS virus sample scanning, and storing and analyzing machine data associated with the EOSs, the SMSs, and the VDCSs.
    Type: Application
    Filed: October 31, 2021
    Publication date: April 7, 2022
    Applicant: BORRIES PTE. LTD.
    Inventors: Zhongwei Chen, Xiaoming Chen, Daniel Tang, Liang-Fu Fan
  • Publication number: 20220108867
    Abstract: The present invention provides a digital high-resolution detector for detecting X-ray, UV light or charged particles. In various embodiments, the digital detector comprises an array of CMOS or CCD pixels and a layer of conversion material on top of the array designed for converting incident X-ray, UV light or charged particles into photons for CMOS or CCD sensors to capture. The thin and high-resolution detector of the invention is particularly useful for monitoring and aligning beams in, and optimizing system performance of, an apparatus of charged-particle beam e.g. an electron microscope.
    Type: Application
    Filed: July 8, 2021
    Publication date: April 7, 2022
    Applicant: BORRIES PTE. LTD.
    Inventors: Zhongwei Chen, Xiaoming Chen, Daniel Tang, Liang-Fu Fan
  • Publication number: 20220108865
    Abstract: The present invention provides an apparatus of charged-particle beam such as an electron microscope with co-condensers. A source of charged particles is configured to emit a beam of charged particles, and the co-condensers including two or more magnetic condensers are configured to coherently focus the beam to a single crossover spot. The invention exhibits numerous technical merits such as continuous image resolution tuning, and automatic switching between multiple resolutions, among others.
    Type: Application
    Filed: April 21, 2021
    Publication date: April 7, 2022
    Applicant: BORRIES PTE. LTD.
    Inventors: Zhongwei Chen, Xiaoming Chen, Daniel Tang, Liang-Fu Fan
  • Publication number: 20220108869
    Abstract: The present invention provides a driving system comprising two actuators for moving a stage through two elastic connectors; and a general apparatus/device comprising such a driving system, such as a machine tool, an analytical instrument, an optical microscope, and an apparatus of charged-particle beam such as electron microscope and an electron beam lithographical apparatus. When used in an electron microscope, the stage can be used as a specimen stage or a plate having apertures for electron beam to pass through. The novel stage driving system exhibits numerous technical merits such as simpler structure, better manufacturability, improved cost-effectiveness, and higher reliability, among others.
    Type: Application
    Filed: August 1, 2021
    Publication date: April 7, 2022
    Applicant: BORRIES PTE. LTD.
    Inventors: Zhongwei Chen, Xiaoming Chen, Daniel Tang, Liang-Fu Fan
  • Publication number: 20220108668
    Abstract: A display system includes a host and a display. The host executes a first application and a program. The program sets a first display parameter corresponding to the first application. The display receives a signal provided by the host. The signal includes a desktop. The first application is operated at a first window on the desktop. The program outputs the first display parameter to the display. The display sets the first window with the first display parameter and displays, and displays the non-first window area of the desktop with a preset display parameter.
    Type: Application
    Filed: July 7, 2021
    Publication date: April 7, 2022
    Applicant: Qisda Corporation
    Inventors: Yu-Fu FAN, Yi-Ming HUANG, Yu-Chun LIN
  • Patent number: 11295927
    Abstract: The present invention provides an apparatus of charged-particle beam such as an electron microscope with co-condensers. A source of charged particles is configured to emit a beam of charged particles, and the co-condensers including two or more magnetic condensers are configured to coherently focus the beam to a single crossover spot. The invention exhibits numerous technical merits such as continuous image resolution tuning, and automatic switching between multiple resolutions, among others.
    Type: Grant
    Filed: April 21, 2021
    Date of Patent: April 5, 2022
    Assignee: BORRIES PTE. LTD.
    Inventors: Zhongwei Chen, Xiaoming Chen, Daniel Tang, Liang-Fu Fan
  • Patent number: 11257659
    Abstract: The present invention provides an electrode assembly comprising two or more electrodes arranged around a primary axis forming a non-cylindrical channel space. General electronic apparatus/device, particularly apparatus of charged-particle beam such as electron microscope, may use the electrode assembly to create an optimized pattern of electrical field within non-cylindrical channel space. When the electrode assembly is used as a beam deflector in a magnetic objective lens, the electrical field within the central channel space can be co-optimized with the magnetic field for reducing aberration(s) such as distortion, field curvature, astigmatism, and chromatic aberration, after the beam passes through the central channel space.
    Type: Grant
    Filed: May 12, 2021
    Date of Patent: February 22, 2022
    Assignee: BORRIES PTE. LTD.
    Inventors: Zhongwei Chen, Xiaoming Chen, Daniel Tang, Liang-Fu Fan
  • Publication number: 20220003405
    Abstract: A display system and a control method are provided. The display system includes a display device, an illumination device and a control circuit. The display device includes a display panel. The display panel is configured to display an image frame. The illumination device is movably disposed on the display device. The illumination device selectively projects light in a first direction or in a second direction different from the first direction. When the illumination device projects the light in the first direction, the control circuit generates a first control signal so as to control the illumination device to perform a first illumination mode. When the illumination device projects the light in the second direction, the control circuit generates a second control signal so as to control the illumination device to perform a second illumination mode different from the first illumination mode.
    Type: Application
    Filed: June 21, 2021
    Publication date: January 6, 2022
    Applicant: QISDA CORPORATION
    Inventors: Hsin-Che Hsieh, Wei-Jou Chen, Yu-Fu Fan, Po-Fu Wu
  • Patent number: 11218027
    Abstract: A light-emitting wireless charging structure includes a base, a wireless charging module, a light-emitting element and an upper cover. The wireless charging module is disposed on the base. The light-emitting element is disposed on the base adjacent to the wireless charging module. The upper cover covers the wireless charging module and the light-emitting element. The upper cover has a lower surface facing the wireless charging module and an upper surface opposite to the bottom surface. When the light-emitting element emits light, light coming from the light-emitting element passes through the upper cover and forms a mark on the upper surface to indicate the position of the wireless charging module. When the light-emitting element is turn off or kept in an off state, either the mark that has been formed on the upper surface disappears therefrom or no any mark is ever shown on the top surface.
    Type: Grant
    Filed: November 28, 2019
    Date of Patent: January 4, 2022
    Assignee: Qisda Corporation
    Inventors: Yung-Yeh Chang, Ting-Hui Chih, Chen-Yang Hu, Jui-Chien Lu, Hung-Wu Lin, Wen-Hung Li, Yu-Fu Fan, Che-Wei Shen, Tung-Hsien Tsai, Yen-Chen Chiang
  • Patent number: 11094499
    Abstract: The present invention provides an apparatus of charged-particle beam such as an electron microscope including a specimen table that can slide on a planar surface around the lower pole piece of the objective lens. The specimen table is confined in a specimen stage having one elastic protrusion and one or more elastic force receiving parts (e.g three permanent protrusions) that contact and press the table. When the specimen is under microscopic examination, disturbing vibration cannot generate a force sufficient to overcome the limiting friction between the specimen table and the planar surface of the objective lens. The invention exhibits numerous technical merits such as minimal or zero vibration noise, and improved image quality, among others.
    Type: Grant
    Filed: February 18, 2021
    Date of Patent: August 17, 2021
    Assignee: BORRIES PTE. LTD.
    Inventors: Zhongwei Chen, Xiaoming Chen, Daniel Tang, Liang-Fu Fan
  • Publication number: 20210232295
    Abstract: A control method of displayed picture for a display includes: displaying a displayed picture, wherein the displayed picture includes a first picture area and a second picture area, the first picture area displays an image signal provided by a first host, the second picture area displays an image signal provided by a second host; moving a cursor in the displayed picture to a first boundary of the second picture area where the cursor has first positioning coordinates; dragging the first boundary by the cursor towards the first picture area, such that the cursor is moved to second positioning coordinates; and updating an appearance of the second picture area according to the second positioning coordinates.
    Type: Application
    Filed: January 12, 2021
    Publication date: July 29, 2021
    Inventors: Chen-Yang Hu, Yu-Fu Fan, Hung-Wu Lin, Wan-Wei Chi, Chang-Cheng Chen
  • Publication number: 20210198638
    Abstract: The present invention relates to non-naturally occurring polypeptides useful for preparing armodafinil, polynucleotides encoding the polypeptides, and methods of using the polypeptides. The non-naturally occurring polypeptides of the present invention are effective in carrying out biocatalytic conversion of the (i) 2-(benzhydrylsulfinyl)acetamide to (?)-2-[(R)-(diphenylmethyl)sulfinyl]acetamide (armodafinil), or (ii) benzhydryl-thioacetic acid to (R)-2-(benzhydrylsulfinyl)acetic acid, which is a pivotal intermediate in the synthesis of armodafinil, in enantiomeric excess.
    Type: Application
    Filed: February 24, 2021
    Publication date: July 1, 2021
    Inventors: Ee Lui Ang, Oscar Alvizo, Behnaz Behrouzian, Michael D. Clay, Steven J. Collier, Ellen D. Eberhard, Fu Fan, Shiwei Song, Derek J. Smith, Magnus Widegren, Robert Wilson, Junye Xu, Jun Zhu
  • Patent number: 10961517
    Abstract: The present invention relates to non-naturally occurring polypeptides useful for preparing armodafinil, polynucleotides encoding the polypeptides, and methods of using the polypeptides. The non-naturally occurring polypeptides of the present invention are effective in carrying out biocatalytic conversion of the (i) 2-(benzhydrylsulfinyl)acetamide to (?)-2-[(R)-(diphenylmethyl)sulfinyl]acetamide (armodafinil), or (ii) benzhydryl-thioacetic acid to (R)-2-(benzhydrylsulfinyl)acetic acid, which is a pivotal intermediate in the synthesis of armodafinil, in enantiomeric excess.
    Type: Grant
    Filed: August 17, 2020
    Date of Patent: March 30, 2021
    Assignee: Codexis, Inc.
    Inventors: Ee Lui Ang, Oscar Alvizo, Behnaz Behrouzian, Michael D. Clay, Steven J. Collier, Ellen D. Eberhard, Fu Fan, Shiwei Song, Derek J. Smith, Magnus Widegren, Robert Wilson, Junye Xu, Jun Zhu
  • Publication number: 20210088706
    Abstract: A lens assembly is provided, including: a barrel, at least one plastic lens and at least one coating film. The at least one plastic lens is assembled in the barrel. The at least one coating film is disposed on a surface of the at least one plastic lens and includes a plurality of coating layers which include at least one high refractive coating layer and at least one low refractive coating layer. A refractive index of the at least one high refractive coating layer is larger than a refractive index of the at least one low refractive coating layer. A thickness of each of the at least one coating film is larger than or equal to 3 micrometers.
    Type: Application
    Filed: September 23, 2019
    Publication date: March 25, 2021
    Inventors: Kuo-Fu Fan, Hsin-Yu Lin, Tsung-Chi Tsai
  • Publication number: 20210011246
    Abstract: A lens with shielding structure includes a main body. The main body defines an axial direction. The main body includes an optical portion and a shielding portion. The optical portion is located at a center of the main body. The shielding portion is annular to surround the optical portion. The shielding portion includes a micro structure and a shielding layer. The micro structure includes a plurality of recesses formed on the main body. The shielding layer is coated on the micro structure to fill the recesses up.
    Type: Application
    Filed: July 10, 2019
    Publication date: January 14, 2021
    Inventors: Kuo-Fu Fan, Hung-Ta Chen, Tsung-Chi Tsai
  • Publication number: 20210011568
    Abstract: An electronic device with fingerprint identification mechanism includes a touch panel, a camera unit, and a processing unit. A part of the touch panel is defined as a recognition area. The touch panel is adapted for at least one finger to touch for controlling. The camera unit is arranged under the touch panel. The camera unit includes a plurality of camera devices spacedly arranged. The camera devices face the touch panel. Projections of imaging ranges of the camera devices on the touch panel partially overlap so that the recognition area is covered by the projections of the imaging ranges of the camera devices. The processing unit is electrically connected to the touch panel and the camera unit respectively.
    Type: Application
    Filed: July 10, 2019
    Publication date: January 14, 2021
    Inventors: Kuo-Fu Fan, Hung-Ta Chen, Tsung-Chi Tsai