Abstract: A composite anti-restenosis drug for use with a coronary drug-eluting stent, and a controlled release system for the drug. The composite drug comprises arsenic trioxide and rapamycin, which may be used in combination to prevent in-stent restenosis and reduce the incidence of intravascular thrombosis. The controlled release system for the composite drug may control the release of the composite drug so as to achieve the therapeutic effect of controlling restenosis and preventing the formation of thromboses.

Abstract: Systems and methods are described for laser bonding polymer catheter components by using laser energy to create localized heat fusion bonds between two or more polymer catheter components.

Abstract: A method of providing a hermetically sealed enclosure for a highly moisture sensitive electronic device including depositing an electrical conductor on the substrate which provides an electrical connection with the electronic device and depositing an electrically insulating thin layer over the electrical conductor; providing a low melting point indium metal or alloy in the form of a wire having diameter ranging from 1 mil to 10 mils on the electrically insulating thin layer on the substrate so that the wire is situated around the periphery of the electronic device; placing an ultrasonic horn over the cover plate so that ultrasonic energy can be delivered through the cover plate to the wire and applying a pressure between 20 and 100 psi; and providing an acoustic wave to melt the wire.

Abstract: An intraoral x-ray film packet is taught which includes a molded thermoplastic frame (preferably injection molded) to which an x-ray dental packet is sealed. The sealing method can be any one of a number of processes including, but not limited to RF sealing, induction heat sealing, or ultrasonic sealing, as well as using any one of various adhesives to affix the x-ray dental packet to the frame. The injection molded thermoplastic frame provides a cushion to buffer and a soft rounded edge to mask the sharp edges that occur on plastic encased x-ray dental packets. Sealing of the injection molded thermoplastic frame to the x-ray dental packet during manufacture results in a packet which includes a comfort enhancing perimeter frame permanently integrated therewith. In such manner, the dental film packet is manufactured with an integrally formed perimetric cushion. The dental film packet is preferably formed with an outer envelope wherein one of the opposing outer sheets is more rigid than the other.

Abstract: A method and apparatus for embossing plastic web materials, for instance, low density polyethylene film, have a movable, first embossing element having a plurality of male dies associated with a heat transferable member and a stationary, second embossing element having a plurality of female dies. The temperature of the heat transferable member is controllable so that the male dies can deform a range of deformable plastic materials. The stationary, second embossing element is alignable relative to the first embossing element and unheated so that the female dies are maintained at about ambient temperature during embossing.

Abstract: A method and apparatus for evaluating the end cap round transducer horn assemblies used in debubbling operations wherein the ECR THA can be evaluated off-line at both high and low power and on-line by making electrical measurements on the ECR THA. The electrical measurements are used to characterize the physical condition of the piezoelectric ceramics of the THA. A test box is employed to practice the method. The test box is connected between the THA and a signal analyzer. Power is supplied to the THA and the electrical signals across the THA are sampled. The sampled electrical signals are transmitted to the signal analyzer while maintaining the amplitude and phase relationship thereof. The sampled electrical signals are used to generate an impedance trace for the particular THA. That impedance trace is compared to a model impedance trace. In such manner, it can be determined whether the ECR THA is operational.

Abstract: A method of providing a hermetically sealed enclosure for a highly moisture sensitive electronic device including depositing an electrical conductor on the substrate which provides an electrical connection with the electronic device and depositing an electrically insulating thin layer over the electrical conductor; providing a low melting point indium metal or alloy in the form of a wire having diameter ranging from 1 mil to 10 mils on the electrically insulating thin layer on the substrate so that the wire is situated around the periphery of the electronic device; placing an ultrasonic horn over the cover plate so that ultrasonic energy can be delivered through the cover plate to the wire and applying a pressure between 20 and 100 psi; and providing an acoustic wave to melt the wire.

Abstract: A self-contained photohardenable imaging assembly comprising in order: a first transparent support; an imaging layer comprising a developer material and a plurality of photohardenable microcapsules encapsulating a color precursor, and a second support, wherein at least one support comprises a barrier layer that exhibits a low water vapor transmission rate. The imaging assembly has been found to provide better image quality and more consistence sensitometric response to pressure development.

Abstract: A method and apparatus for embossing plastic web materials, for instance, low density polyethylene film, have a movable, first embossing element having a plurality of male dies associated with a heat transferable member and a stationary, second embossing element having a plurality of female dies. The temperature of the heat transferable member is controllable so that the male dies can deform a range of deformable plastic materials. The stationary, second embossing element is alignable relative to the first embossing element and unheated so that the female dies are maintained at about ambient temperature during embossing.

Abstract: A method and apparatus for evaluating the end cap round transducer horn assemblies used in debubbling operations wherein the ECR THA can be evaluated off-line at both high and low power and on-line by making electrical measurements on the ECR THA. The electrical measurements are used to characterize the physical condition of the piezoelectric ceramics of the THA. A test box is employed to practice the method. The test box is connected between the THA and a signal analyzer. Power is supplied to the THA and the electrical signals across the THA are sampled. The sampled electrical signals are transmitted to the signal analyzer while maintaining the amplitude and phase relationship thereof. The sampled electrical signals are used to generate an impedance trace for the particular THA. That impedance trace is compared to a model impedance trace. In such manner, it can be determined whether the ECR THA is operational.

Abstract: A method and apparatus for evaluating the end cap round transducer horn assemblies used in debubbling operations wherein the ECR THA can be evaluated off-line at both high and low power and on-line by making electrical measurements on the ECR THA. The electrical measurements are used to characterize the physical condition of the piezoelectric ceramics of the THA. A test box is employed to practice the method. The test box is connected between the THA and a signal analyzer. Power is supplied to the THA and the electrical signals across the THA are sampled. The sampled electrical signals are transmitted to the signal analyzer while maintaining the amplitude and phase relationship thereof. The sampled electrical signals are used to generate an impedance trace for the particular THA. That impedance trace is compared to a model impedance trace. In such manner, it can be determined whether the ECR THA is operational.

Abstract: A method and apparatus for evaluating the end cap round transducer horn assemblies used in debubbling operations wherein the ECR THA can be evaluated off-line at both high and low power and on-line by making electrical measurements on the ECR THA. The electrical measurements are used to characterize the physical condition of the piezoelectric ceramics of the THA. A test box is employed to practice the method. The test box is connected between the THA and a signal analyzer. Power is supplied to the THA and the electrical signals across the THA are sampled. The sampled electrical signals are transmitted to the signal analyzer while maintaining the amplitude and phase relationship thereof. The sampled electrical signals are used to generate an impedance trace for the particular THA. That impedance trace is compared to a model impedance trace. In such manner, it can be determined whether the ECR THA is operational.

Abstract: A method and apparatus for evaluating the end cap round transducer horn assemblies used in debubbling operations wherein the ECR THA can be evaluated off-line at both high and low power and on-line by making electrical measurements on the ECR THA. The electrical measurements are used to characterize the physical condition of the piezoelectric ceramics of the THA. A test box is employed to practice the method. The test box is connected between the THA and a signal analyzer. Power is supplied to the THA and the electrical signals across the THA are sampled. The sampled electrical signals are transmitted to the signal analyzer while maintaining the amplitude and phase relationship thereof. The sampled electrical signals are used to generate an impedance trace for the particular THA. That impedance trace is compared to a model impedance trace. In such manner, it can be determined whether the ECR THA is operational.

Abstract: A method and apparatus for evaluating the end cap round transducer horn assemblies used in debubbling operations wherein the ECR THA can be evaluated off-line at both high and low power and on-line by making electrical measurements on the ECR THA. The electrical measurements are used to characterize the physical condition of the piezoelectric ceramics of the THA. A test box is employed to practice the method. The test box is connected between the THA and a signal analyzer. Power is supplied to the THA and the electrical signals across the THA are sampled. The sampled electrical signals are transmitted to the signal analyzer while maintaining the amplitude and phase relationship thereof. The sampled electrical signals are used to generate an impedance trace for the particular THA. That impedance trace is compared to a model impedance trace. In such manner, it can be determined whether the ECR THA is operational.

Abstract: An ultrasonic apparatus and method for cutting a non-planar workpiece. The apparatus includes an anvil having a non-planar surface for closely engaging an underside of the workpiece. An ultrasonic horn has a non-planar cutting surface closely receiving a topside of the workpiece, wherein the cutting surface and the support surface have complementary non-planar shapes. The ultrasonic horn resonates at a predetermined frequency effect cutting of the workpiece. If the workpiece has a heat fusible component, the workpiece can also be seamed.

Abstract: Apparatus for heating and venting a container. The apparatus has a heating station for the container. A heater is disposed to supply heat to the heating station. A drive has a body and a reciprocable member. The body is mounted in predetermined relation to the receiving station. The reciprocable member is movable relative to the receiving station between a first position and a second position. A cannula is joined to the reciprocable member. The cannula has a hollow bore. The cannula is movable between a retracted position and an extended position by movement of the reciprocable member between the first position and the second position. A vent line communicates with the bore and the ambient environment.

Abstract: An ultrasonic apparatus and method for cutting a non-planar workpiece. The apparatus includes an anvil having a non-planar surface for closely engaging an underside of the workpiece. An ultrasonic horn has a non-planar cutting surface closely receiving a topside of the workpiece, wherein the cutting surface and the support surface have complementary non-planar shapes. The ultrasonic horn resonates at a predetermined frequency effect cutting of the workpiece. If the workpiece has a heat fusible component, the workpiece can also be seamed.

Abstract: A container for sterilizing objects contained in a pouch (66) is provided with shield portions (30, 32) having a wiper fingers (42) located on at least one side edge portion (44) of a peripheral edge (40) of one of the shield portions (30, 32). The wiper fingers (42) insure that metal-to-metal contact is maintained between the shield portions (30, 32) during sterilization. The pouch (66) is constructed from two sheets of a laminate materials, and includes an instrument retaining portion (68) and a fluid retaining portion (70). A water pillow (80) that bursts during sterilization is provided within the fluid retaining portion (70). Alternatively, a temporary seal (86) that bursts or opens during sterilization is provided within the fluid retaining portion (70) to prevent the premature transfer of a sterilization fluid contained in the fluid retaining portion (70) to the instrument retaining portion (68).

Abstract: A temperature sensor for use in a microwave oven includes a metallic housing including a sleeve with a central passage, a metallic top plate coupled to the metallic housing to close off a first end of the central passage, and a temperature dependent resistor sensor element thermally coupled with the metallic plate. The sensor element is coupled to a signal transmission cable that passes through a bottom cap which closes off the other end of the central passage. The transmission cable is preferably connected to the bottom cap by soldering around the entire interface of the cable with the bottom cap. The cable includes at least 90% shielding and plastic insulation sufficient to resist temperatures up to 200 degrees centigrade. The sleeve is preferably filled with an epoxy cement that surrounds the sensor element.

Abstract: A container for sterilizing objects contained in a pouch (66) is provided with shield portions (30, 32) having a wiper fingers (42) located on at least one side edge portion (44) of a peripheral edge (40) of one of the shield portions (30, 32). The wiper fingers (42) insure that metal-to-metal contact is maintained between the shield portions (30, 32) during sterilization. The pouch (66) is constructed from two sheets of a laminate materials, and includes an instrument retaining portion (68) and a fluid retaining portion (70). A water pillow (80) that bursts during sterilization is provided within the fluid retaining portion (70). Alternatively, a temporary seal (86) that bursts or opens during sterilization is provided within the fluid retaining portion (70) to prevent the premature transfer of a sterilization fluid contained in the fluid retaining portion (70) to the instrument retaining portion (68).