Abstract: A stent of variable surface area as determined by stent struts. The stent can have a variable surface area per unit length which accommodates a therapeutic agent. A patterned distribution of therapeutic agent can be provided throughout the stent. The stent can have an increased level of therapeutic agent near an end of the stent. A decreased level of therapeutic agent can be provided near an end of one embodiment of a stent. Indentations can be provided at the surface of the stent with therapeutic agent disposed therein. The stent can be cut with struts of variable thickness to provide the variable stent surface area.

Abstract: The invention is generally directed to methods of radiation processing and methods for routine dosimetry, such as for the measurement of radiation dosages delivered to items to be processed by the application of radiation. Radiation-induced heat in an irradiated item is measured with a calorimeter and used to determine the dose of radiation received by the item. Resistive elements such as thermistors may be used in calorimeters to measure the change in temperature of an item receiving radiation, such as in electron beam radiation. Calorimeters exposed to irradiation in the same manner as irradiated items provide routine dosimetry for radiation processing.

Abstract: A coating for a medical device, particularly for a drug eluting stent, is described. The coating comprises a polymer having a weight-average molecular weight between about 200,000 and about 250,000 Daltons or a polydispersity index between about 2.6 and about 3.0.

Abstract: The invention is directly related to methods of radiation processing and methods for routine dosimetry, such as for the measurement of radiation dosages delivered to items to be processed by the application of radiation. Radiation-induced heat in an irradiated item is measured with a calorimeter and used to determine the dose of radiation received by the item. Resistive elements such as thermistors may be used in calorimeters to measure the change in temperature of an item receiving radiation, such as in electron beam radiation. Calorimeters exposed to irradiation in the same manner as irradiated items provide routine dosimetry for radiation processing.

Abstract: A method for delivering multiple doses of radiation to a target area of a vessel. The method includes delivering multiple radioisotopes to a target area of a vessel and allowing the radioisotopes to dwell in the target area for a period of time to deliver a predetermined and uniform radiation dose.