Patents by Inventor Fujii Tomoko

Fujii Tomoko has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Modified hepatitis B virus surface antigen P31 and production thereof
    Patent number: 5164485
    Abstract: A modified protein (i) derived from a hepatitis B virus surface antigen P31 protein and (ii) having hepatitis B virus surface antigen activity and the ability to bind polymerized human serum albumin, wherein the modification comprises rendering at least one trypsin-like protease sensitive site of the hepatitis B virus surface antigen P31 protein insensitive. The modified protein can be used in the production of a vaccine for prevention of hepatitis B virus infections and as an antigen for diagnosis of hepatitis B virus infections.
    Type: Grant
    Filed: July 3, 1990
    Date of Patent: November 17, 1992
    Assignee: Takeda Chemical Industries, Ltd.
    Inventors: Fujisawa Yukio, Itoh Yasuaki, Nishimura Osamu, Fujii Tomoko
  • DNA sequence encoding modified hepatitis B virus surface antigen P31 protein
    Patent number: 4983520
    Abstract: A modified protein (i) derived from a hepatitis B virus surface antigen P31 protein and (ii) having hepatitis B virus surface antigen activity and the ability to bind polymerized human serum albumin, wherein the modification comprises rendering at least one trypsin-like protease sensitive site of the hepatitis B virus surface antigen P31 protein insensitive. The modified protein can be used in the production of a vaccine for prevention of hepatitis B virus infections and as an antigen for diagnosis of hepatitis B virus infections.
    Type: Grant
    Filed: August 20, 1986
    Date of Patent: January 8, 1991
    Assignee: Takeda Chemical Industries, Ltd.
    Inventors: Fujisawa Yukio, Itoh Yasuaki, Nishimura Osamu, Fujii Tomoko