Abstract: A method and a device for improving pipeline safety of a space-terrestrial network architecture. The method pre-registers the profile of a base station in the network repository function network element of a 5G core network; after receiving a relay pipeline connection establishment request initiated by a base station, a relay satellite sends a network function verification request to the network repository function network element through a network expose function network element; after receiving a response to a network function discovery request of the base station, the network expose function network element sets the corresponding verification result of the base station according to whether there is base station registration information and responds to a verification request of the network element; and finally, the relay satellite verifies the verification result cell carried in the received response to determine the legality of the current access to the base station.

Abstract: Steroid derivative regulators, a method for preparing the same, and uses thereof are described. Specifically, a compound of formula (I), a preparation method therefor, a pharmaceutical composition containing the compound, and uses thereof as a regulator the of GABAA receptor for treating depression, convulsion, Parkinson's disease, and nervous system diseases are described, wherein the substituents of the formula (I) are as defined in the description.

Abstract: An incremental compiling method and an incremental compiling system based on a heterogeneous device. The method comprises: a user using P4 to develop a network program, checking the syntax and semantics of the network program and converting into an intermediate representation; allocating intermediate representation files according to constraints such as the functions and resources of the heterogeneous device; then, transforming the network program into different rule expressions of the heterogeneous device according to the constraints of the heterogeneous device, flow table entries and the like, and loading the on different rule expressions to a target device; when the user needs to deploy network functions incrementally, the user only needs to write new network programs and regenerate rule expressions; by comparing and analyzing the old and new rule expressions, a rule expression that can be loaded on heterogeneous device is formed, and the incremental deployment of network functions is realized.

Abstract: Steroid derivative regulators, a method for preparing the same, and uses thereof are described. Specifically, a compound of formula (I), a preparation method therefor, a pharmaceutical composition containing the compound, and uses thereof as a regulator the of GABAA receptor for treating depression, convulsion, Parkinson's disease, and nervous system diseases are described, wherein the substituents of the formula (I) are as defined in the description.

Abstract: A guiding and positioning device for assisting in computed tomography-guided needle biopsy (CT-GNB) includes a control mechanism and an actuating mechanism, where the actuating mechanism includes a base and a support frame; one of the two head ends of the support frame is provided with a locking mechanism; a positioning apparatus includes a first guide rail in an arc shape, and the first guide rail is slidably provided with a guiding apparatus configured to guide different puncture angles in a same plane; the guiding apparatus includes a deflection drive mechanism slidable along the first guide rail, and a first translation mechanism and a second translation mechanism that are arranged perpendicular to each other; and the second translation mechanism is slidably provided with a guiding mechanism configured to guide a puncture through a visible laser space.

Abstract: The present invention provides radioactive glass microspheres for embolization and a preparation method and an application thereof. A nuclide oxide and a foaming agent are added into a glass matrix, blended and uniformly mixed for making the foaming agent decomposed and vaporized at a high temperature to generate bubbles, so as to prepare the radioactive glass microspheres for embolization with cavities. The radioactive glass microspheres for embolization have a density of 1.4-2.3 g/cm3, a nuclide loading rate of 15-40 wt % and a higher and more stable radiation dose, can achieve better distribution and deposition effects in liver blood vessels after injection, and can achieve a better therapeutic effect for hepatocellular carcinoma (HCC).

Abstract: The present invention provides radioactive glass microspheres for embolization and a preparation method and an application thereof. A nuclide oxide and a foaming agent are added into a glass matrix, blended and uniformly mixed for making the foaming agent decomposed and vaporized at a high temperature to generate bubbles, so as to prepare the radioactive glass microspheres for embolization with cavities. The radioactive glass microspheres for embolization have a density of 1.4-2.3 g/cm3, a nuclide loading rate of 15-40 wt % and a higher and more stable radiation dose, can achieve better distribution and deposition effects in liver blood vessels after injection, and can achieve a better therapeutic effect for hepatocellular carcinoma (HCC).

Abstract: Disclosed are methods, systems, and non-transitory computer-readable medium for generating recommendations regarding products. A method may include determining a set of content features including one or more product attributes; determining a set of latent features; receiving a query user identifier and a query product identifier; determining a feature vector associated with the query user identifier and the query product identifier based on the set of content features and the set of latent features; determining one or more model coefficients for a linear model; and utilizing the linear model to determine a fit score for the query user identifier and the query product identifier.

Abstract: Disclosed herein are methods for analyzing quantitative expression values of biomarkers of a biomarker panel for determining multiple sclerosis disease activity (e.g., multiple sclerosis disease progression) in a human subject. Further disclosed herein are kits for measuring quantitative expression values of the markers as well as computer systems and software embodiments of predictive models for determining multiple sclerosis disease activity (e.g., multiple sclerosis disease progression) in human subjects based on the quantitative expression values of the markers.

Abstract: Disclosed are methods, systems, and non-transitory computer-readable medium for generating recommendations regarding products. A method may include determining a set of content features including one or more product attributes; determining a set of latent features; receiving a query user identifier and a query product identifier; determining a feature vector associated with the query user identifier and the query product identifier based on the set of content features and the set of latent features; determining one or more model coefficients for a linear model; and utilizing the linear model to determine a fit score for the query user identifier and the query product identifier.

Abstract: The present invention discloses a glass material, and a preparation method and a product thereof. The glass material contains a lithium salt crystalline phase and a phosphate crystalline phase. For the entire material, the crystallinity is 40-95%, the lithium salt crystalline phase accounts for 40-90 wt % of the entire material, and the phosphate crystalline phase accounts for 2-15 wt % of the entire material, wherein the lithium salt crystalline phase is one or more of lithium silicate, lithium disilicate and petalite, and the phosphate crystalline phase is aluminum phosphate or/and aluminum metaphosphate. After the glass material of the present invention is toughened, the Vickers hardness (Hv) is 900 kgf/mm2 or above. The glass material or a substrate of the present invention is suitable for protective members such as mobile terminal equipment and optical equipment and has high hardness and strength.

Abstract: An anti-B7-H4 antibody, an antigen-binding fragment thereof and pharmaceutical use thereof. A chimeric antibody and a humanized antibody comprising a CDR region of the anti-B7-H4 antibody, a pharmaceutical composition comprising the anti-B7-H4 antibody and the antigen-binding fragment thereof, and use thereof as an anti-cancer medicament. A humanized anti-B7-H4 antibody and use thereof in the preparation of a medicament for treating diseases or conditions mediated by B7-H4.

Abstract: The present invention provides a protein-based biomarker that is useful in qualifying ovarian cancer status in a patient. In particular, the biomarker of this invention is useful to classify a subject sample as ovarian cancer or non-ovarian cancer. The biomarker can be detected by SELDI mass spectrometry.

Abstract: Disclosed are methods, systems, and non-transitory computer-readable medium for generating recommendations regarding products. A method may include determining a set of content features including one or more product attributes; determining a set of latent features; receiving a query user identifier and a query product identifier; determining a feature vector associated with the query user identifier and the query product identifier based on the set of content features and the set of latent features; determining one or more model coefficients for a linear model; and utilizing the linear model to determine a fit score for the query user identifier and the query product identifier.

Abstract: Disclosed are methods, systems, and non-transitory computer-readable medium for generating recommendations regarding products. A method may include determining a set of content features including one or more product attributes; determining a set of latent features; receiving a query user identifier and a query product identifier; determining a feature vector associated with the query user identifier and the query product identifier based on the set of content features and the set of latent features; determining one or more model coefficients for a linear model; and utilizing the linear model to determine a fit score for the query user identifier and the query product identifier.

Abstract: The present invention provides a protein-based biomarker that is useful in qualifying ovarian cancer status in a patient. In particular, the biomarker of this invention is useful to classify a subject sample as ovarian cancer or non-ovarian cancer. The biomarker can be detected by SELDI mass spectrometry.

Abstract: Disclosed are methods, systems, and non-transitory computer-readable medium for generating recommendations regarding products. A method may include determining a set of content features including one or more product attributes; determining a set of latent features; receiving a query user identifier and a query product identifier; determining a feature vector associated with the query user identifier and the query product identifier based on the set of content features and the set of latent features; determining one or more model coefficients for a linear model; and utilizing the linear model to determine a fit score for the query user identifier and the query product identifier.

Abstract: An amide derivative inhibitor and a preparation method and an application thereof. Specifically relating to the compound shown in general formula (I), a preparation method for same, a pharmaceutical composition comprising said compound, and an application of same as an ASK inhibitor for the treatment of neurodegenerative disease, cardiovascular disease, inflammation, autoimmune and metabolic disease, each of the substituents in the general formula (I) being as defined in the description.

Abstract: Steroid derivative regulators, a method for preparing the same, and uses thereof are described. Specifically, a compound of formula (I), a preparation method therefor, a pharmaceutical composition containing the compound, and uses thereof as a regulator the of GABAA receptor for treating depression, convulsion, Parkinson's disease, and nervous system diseases are described, wherein the substituents of the formula (I) are as defined in the description.

Abstract: An anti-B7-H4 antibody, an antigen-binding fragment thereof and pharmaceutical use thereof. A chimeric antibody and a humanized antibody comprising a CDR region of the anti-B7-H4 antibody, a pharmaceutical composition comprising the anti-B7-H4 antibody and the antigen-binding fragment thereof, and use thereof as an anti-cancer medicament. A humanized anti-B7-H4 antibody and use thereof in the preparation of a medicament for treating diseases or conditions mediated by B7-H4.