Patents by Inventor Fumi EBISU

Fumi EBISU has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for inducing pluripotent stem cells to differentiate into somatic cells
    Patent number: 11959103
    Abstract: Provided is a method for inducing pluripotent stem cells to differentiate into somatic cells in a culture medium containing a heparin binding growth factor, the method comprising bringing cells into contact with a conjugate of a laminin E8 fragment and a growth factor binding domain-containing fragment of a heparan sulfate proteoglycan. According to the present invention, pluripotent stem cells can be induced to differentiate into any desired somatic cells in a highly efficient manner.
    Type: Grant
    Filed: November 9, 2017
    Date of Patent: April 16, 2024
    Assignees: OSAKA UNIVERSITY, KYOTO UNIVERSITY
    Inventors: Kiyotoshi Sekiguchi, Fumi Ebisu, Hidetoshi Sakurai, Mingming Zhao, Megumu Saito
  • METHOD FOR INDUCING PLURIPOTENT STEM CELLS TO DIFFERENTIATE INTO SOMATIC CELLS
    Publication number: 20190276804
    Abstract: Provided is a method for inducing pluripotent stem cells to differentiate into somatic cells in a culture medium containing a heparin binding growth factor, the method comprising bringing cells into contact with a conjugate of a laminin E8 fragment and a growth factor binding domain-containing fragment of a heparan sulfate proteoglycan. According to the present invention, pluripotent stem cells can be induced to differentiate into any desired somatic cells in a highly efficient manner.
    Type: Application
    Filed: November 9, 2017
    Publication date: September 12, 2019
    Applicants: OSAKA UNIVERSITY, KYOTO UNIVERSITY
    Inventors: Kiyotoshi SEKIGUCHI, Fumi EBISU, Hidetoshi SAKURAI, Mingming ZHAO, Megumu SAITO