Patents by Inventor Fumie Futaki
Fumie Futaki has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 9844226Abstract: A substance is described which is capable of imparting a kokumi, which shows a more excellent kokumi-imparting effect, in particular, the initial taste-imparting type of kokumi-imparting effect, which is excellent in the stability and which can easily be produced at a low cost. Additionally, a kokumi-imparting composition which includes a substance as well as a kokumi-imparting agent including the substance and other substances possessing the CaSR agonist activities in combination. More particularly, the present invention herein provides a kokumi-imparting composition consisting of ?-Glu-Abu (L-?-glutamyl-L-2-amino-butyric acid) and a complex kokumi-imparting agent which includes the foregoing substance and another substance having a CaSR agonist activity, in combination.Type: GrantFiled: September 30, 2011Date of Patent: December 19, 2017Assignee: AJINOMOTO CO., INC.Inventors: Fumie Futaki, Reiko Yasuda, Seiichi Sato, Takashi Miyaki, Naohiro Miyamura, Yuzuru Eto
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Patent number: 8568814Abstract: The present invention provides a variety of compounds having a CaSR agonist activity which possesses a superior kokumi-imparting function, and more particularly provides a kokumi-imparting composition, which contains the foregoing compound, and/or another substance having a CaSR agonist activity, in combination. The present invention also provides a kokumi-imparting composition which includes a lanthionine derivative and/or another substance having a CaSR agonist activity.Type: GrantFiled: June 26, 2012Date of Patent: October 29, 2013Assignee: Ajinomoto Co., Inc.Inventors: Seiichi Sato, Fumie Futaki, Reiko Yasuda, Sachise Eto, Yumiko Suzuki, Takaho Tajima, Yuzuru Eto, Yuki Tahara
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Publication number: 20120282386Abstract: The present invention provides a variety of compounds having a CaSR agonist activity which possesses a superior kokumi-imparting function, and more particularly provides a kokumi-imparting composition, which contains the foregoing compound, and/or another substance having a CaSR agonist activity, in combination. The present invention also provides a kokumi-imparting composition which includes a lanthionine derivative and/or another substance having a CaSR agonist activity.Type: ApplicationFiled: June 26, 2012Publication date: November 8, 2012Inventors: Seiichi Sato, Fumie Futaki, Reiko Yasuda, Sachise Eto, Yumiko Suzuki, Takaho Tajima, Yuzuru Eto, Yuki Tahara
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Publication number: 20120034364Abstract: The inventors of this invention have conducted the search for a variety of compounds which may possess a desired CaSR agonist activity to thus find out a substance capable of imparting a kokumi, which shows a more excellent kokumi-imparting effect, in particular, a kokumi-imparting effect of the initial taste-imparting type one, which is excellent in the stability and which can easily be produced at a low cost and the present invention thus provide a kokumi-imparting agent consisting of such a substance as well as a complex kokumi-imparting agent comprising the substance and other substances possessing the CaSR agonist activities in combination. More particularly, the present invention herein provides a kokumi-imparting agent consisting of ?-Glu-Abu (L-?-glutamyl-L-2-amino-butyric acid) and a complex kokumi-imparting agent comprising the foregoing substance and another substance having a CaSR agonist activity, in combination.Type: ApplicationFiled: September 30, 2011Publication date: February 9, 2012Inventors: FUMIE FUTAKI, Reiko Yasuda, Seiichi Sato, Takashi Miyaki, Naohiro Miyamura, Yuzuru Eto
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Publication number: 20100120172Abstract: A method for conveniently detecting binding between the von Willebrand factor and glycoprotein Ib and a means to be used therein. The von Willebrand factor fixed in a reactor immobilized in a reaction vessel in the presence of bottrocetin is bound to a chimeric protein constructed by fusing the carboxyl terminal of a partial protein containing the von Willebrand factor-binding site of glycoprotein Ib with the amino terminal of the Fc region of an immunoglobulin molecule. Then the Fc region of the above immunoglobulin molecule is detected to thereby detect the binding between the von Willebrand factor and the glycoprotein Ib or inhibition of this binding.Type: ApplicationFiled: August 27, 2009Publication date: May 13, 2010Applicant: AJINOMOTO CO., INC.Inventors: Naoyuki Fukuchi, Fumie Futaki, Morikazu Kito, Seiichi Sato, Takayuki Kajiura, Yukitsugu Ono, Koichi Ishii, Akiko Tanaka, Junko Shinozaki, Yasuko Jojima
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Patent number: 7608695Abstract: A method for conveniently detecting binding between the von Willebrand factor and glycoprotein Ib and a means to be used therein. The von Willebrand factor fixed in a reactor immobilized in a reaction vessel in the presence of bottrocetin is bound to a chimeric protein constructed by fusing the carboxyl terminal of a partial protein containing the von Willebrand factor-binding site of glycoprotein Ib with the amino terminal of the Fc region of an immunoglobulin molecule. Then the Fc region of the above immunoglobulin molecule is detected to thereby detect the binding between the von Willebrand factor and the glycoprotein Ib or inhibition of this binding.Type: GrantFiled: April 16, 2004Date of Patent: October 27, 2009Assignee: Ajinomoto Co., Inc.Inventors: Naoyuki Fukuchi, Fumie Futaki, Morikazu Kito, Seiichi Sato, Takayuki Kajiura, Yukitsugu Ono, Koichi Ishii, Akiko Tanaka, Junko Shinozaki, Yasuko Jojima
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Patent number: 7084113Abstract: A method for producing a protein having an antithrombotic activity, which comprises replacing, in a protein that has an amino acid sequence having a homology of not less than 30% to the amino acid sequence of SEQ ID NO: 1 and forms a higher order structure composed of a first ? strand (?1), a first a helix (?1), a second ? helix (?2), a second ? strand (?2), a loop, a third ? strand (?3), a fourth ? strand (?4) and a fifth ? strand (?5) in this order from the amino terminus, at least one amino acid residue in a region from ?2 to ?2 and/or a region from ?3 to ?4 so that electric charge of the amino acid residue is changed towards positive direction.Type: GrantFiled: January 2, 2004Date of Patent: August 1, 2006Assignee: Ajinomoto Co., Inc.Inventors: Naoyuki Fukuchi, Morikazu Kito, Takashi Kayahara, Fumie Futaki, Kohki Ishikawa, Eiichiro Suzuki, Keiko Gondoh, Nobuhisa Shimba, Naoyuki Yamada
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Patent number: 6878811Abstract: A method for conveniently detecting binding between the von Willebrand factor and glycoprotein Ib and a means to be used therein. The von Willebrand factor fixed in a reactor immobilized in a reaction vessel in the presence of bottrocetin is bound to a chimeric protein constructed by fusing the carboxyl terminal of a partial protein containing the von Willebrand factor-binding site of glycoprotein Ib with the amino terminal of the Fc region of an immunoglobulin molecule. Then the Fc region of the above immunoglobulin molecule is detected to thereby detect the binding between the von Willebrand factor and the glycoprotein Ib or inhibition of this binding.Type: GrantFiled: January 13, 1999Date of Patent: April 12, 2005Assignee: Ajinomoto Co., Inc.Inventors: Naoyuki Fukuchi, Fumie Futaki, Morikazu Kito, Koichi Ishii, Akiko Tanaka
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Publication number: 20040229288Abstract: A method for conveniently detecting binding between the von Willebrand factor and glycoprotein Ib and a means to be used therein. The von Willebrand factor fixed in a reactor immobilized in a reaction vessel in the presence of bottrocetin is bound to a chimeric protein constructed by fusing the carboxyl terminal of a partial protein containing the von Willebrand factor-binding site of glycoprotein Ib with the amino terminal of the Fc region of an immunoglobulin molecule. Then the Fc region of the above immunoglobulin molecule is detected to thereby detect the binding between the von Willebrand factor and the glycoprotein Ib or inhibition of this binding.Type: ApplicationFiled: April 16, 2004Publication date: November 18, 2004Applicant: AJINOMOTO CO., INC.Inventors: Naoyuki Fukuchi, Fumie Futaki, Morikazu Kito, Seiichi Sato, Takayuki Kajiura, Yukitsugu Ono, Koichi Ishii, Akiko Tanaka, Junko Shinozaki, Yasuko Jojima
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Publication number: 20040161822Abstract: A method for producing a protein having an antithrombotic activity, which comprises replacing, in a protein that has an amino acid sequence having a homology of not.less than 30% to the amino acid sequence of SEQ ID NO: 1 and forms a higher order structure composed of a first &bgr; strand (&bgr;1), a first a helix (&agr;1), a second &agr; helix (&agr;2), a second &bgr; strand (&bgr;2), a loop, a third &bgr; strand (&bgr;3), a fourth &bgr; strand (&bgr;4) and a fifth &bgr; strand (&bgr;5) in this order from the amino terminus, at least one amino acid residue in a region from &agr;2 to &bgr;2 and/or a region from &bgr;3 to &bgr;4 so that electric charge of the amino acid residue is changed towards positive direction.Type: ApplicationFiled: January 2, 2004Publication date: August 19, 2004Applicant: AJINOMOTO CO., INC.Inventors: Naoyuki Fukuchi, Morikazu Kito, Takashi Kayahara, Fumie Futaki, Kohki Ishikawa, Eiichiro Suzuki, Keiko Gondoh, Nobuhisa Shimba, Naoyuki Yamada
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Patent number: 6710031Abstract: A method for producing a protein having an antithrombotic activity, which comprises replacing, in a protein that has an amino acid sequence having a homology of not less than 30% to the amino acid sequence of SEQ ID NO: 1 and forms a higher order structure composed of a first &bgr; strand (&bgr;1), a first &agr; helix (&agr;1), a second &agr; helix (&agr;2), a second &bgr; strand (&bgr;2), a loop, a third &bgr; strand (&bgr;3), a fourth &bgr; strand (&bgr;4) and a fifth &bgr; strand (&bgr;5) in this order from the amino terminus, at least one amino acid residue in a region from &agr;2 to &bgr;2 and/or a region from &bgr;3 to &bgr;4 so that electric charge of the amino acid residue is changed towards positive direction.Type: GrantFiled: October 4, 2001Date of Patent: March 23, 2004Assignee: Ajinomoto Co., Inc.Inventors: Naoyuki Fukuchi, Morikazu Kito, Takashi Kayahara, Fumie Futaki, Kohki Ishikawa, Eiichiro Suzuki, Keiko Gondoh, Nobuhisa Shimba, Naoyuki Yamada
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Publication number: 20020198363Abstract: A method for producing a protein having an antithrombotic activity, which comprises replacing, in a protein that has an amino acid sequence having a homology of not less than 30% to the amino acid sequence of SEQ ID NO: 1 and forms a higher order structure composed of a first &bgr; strand (&bgr;1), a first &agr; helix (&agr;1), a second &agr; helix (&agr;2), a second &bgr; strand (&bgr;2), a loop, a third &bgr; strand (&bgr;3), a fourth &bgr; strand (&bgr;4) and a fifth &bgr; strand (&bgr;5) in this order from the amino terminus, at least one amino acid residue in a region from &agr;2 to &bgr;2 and/or a region from &bgr;3 to &bgr;4 so that electric charge of the amino acid residue is changed towards positive direction.Type: ApplicationFiled: October 4, 2001Publication date: December 26, 2002Applicant: AJINOMOTO CO., INC.Inventors: Naoyuki Fukuchi, Morikazu Kito, Takashi Kayahara, Fumie Futaki, Kohki Ishikawa, Eiichiro Suzuki, Keiko Gondoh, Nobuhisa Shimba, Naoyuki Yamada