Patents by Inventor Fumihiko Kajii

Fumihiko Kajii has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20190151418
    Abstract: Provided is a means effective in bone regeneration or bone augmentation. Provided is a porous composite containing octacalcium phosphate and parathyroid hormone.
    Type: Application
    Filed: February 24, 2017
    Publication date: May 23, 2019
    Applicant: TOYOBO CO., LTD.
    Inventors: Shinji Kamakura, Satoru Nakajou, Atsushi Iwai, Fumihiko Kajii, Hidenori Tanaka, Kazuo Sasaki
  • Patent number: 9968660
    Abstract: The present invention provides a means effective for bone regeneration or bone augmentation. Provided is a method of bone regeneration or bone augmentation, comprising: implanting a porous composite at a site in need of the bone regeneration or bone augmentation, and administering parathyroid hormone (PTH) to a subject in need of the bone regeneration or bone augmentation, wherein the porous composite comprises calcium phosphate.
    Type: Grant
    Filed: April 8, 2016
    Date of Patent: May 15, 2018
    Assignee: TOYOBO CO., LTD.
    Inventors: Shinji Kamakura, Satoru Nakajou, Atsushi Iwai, Fumihiko Kajii, Hidenori Tanaka
  • Publication number: 20180078676
    Abstract: An object of the present invention is to provide a porous composite that has adequate bending strength and excellent compressive strength and that contains OCP and collagen; and a bone regeneration material containing this porous composite. The present invention provides a porous composite containing octacalcium phosphate and collagen, and having a bending strength of 0.05 to 0.16 MPa and a compressive strength of 0.3 MPa or more.
    Type: Application
    Filed: April 6, 2016
    Publication date: March 22, 2018
    Applicant: TOYOBO CO., LTD.
    Inventors: Atsushi Iwai, Fumihiko Kajii, Hidenori Tanaka
  • Publication number: 20170304492
    Abstract: Provided are a porous composite containing OCP and collagen having higher compressive strength than before: a bone regeneration material containing the same: and a method for producing a porous composite. The porous composite contains octacalcium phosphate and collagen, has a pore size of 5 to 40 ?m as determined by measurement using a mercury porosimeter, and contains pores of 71 to 200 ?m at a rate of less than or equal to 8% in all pores of less than or equal to 200 ?m.
    Type: Application
    Filed: June 12, 2015
    Publication date: October 26, 2017
    Applicant: TOYOBO CO., LTD.
    Inventors: Atsushi Iwai, Fumihiko Kajii, Hidenori Tanaka
  • Publication number: 20170290891
    Abstract: The present invention provides a means effective for bone regeneration or bone augmentation. Provided is a method of bone regeneration or bone augmentation, comprising: implanting a porous composite at a site in need of the bone regeneration or bone augmentation, and administering parathyroid hormone (PTH) to a subject in need of the bone regeneration or bone augmentation, wherein the porous composite comprises calcium phosphate.
    Type: Application
    Filed: April 8, 2016
    Publication date: October 12, 2017
    Applicant: TOYOBO CO., LTD.
    Inventors: Shinji Kamakura, Satoru Nakajou, Atsushi Iwai, Fumihiko Kajii, Hidenori Tanaka
  • Patent number: 9687592
    Abstract: A method for manufacturing a nerve regeneration-inducing tube with excellent pressure resistance, shape recovery property, anti-kink property, film exfoliation resistance, resistance to invasion of outer tissues, and leakage resistance. The tubular body is formed by weaving together fibers made up of biodegradable polymer. The outer surface of the tubular body is coated multiple times with a collagen solution. The lumen of the tubular body is filled with collagen. Viscosity of the collagen solution that is first applied to the outer surface of the tubular body is between 2 to 800 cps. Viscosity of the collagen solution that is subsequently applied is higher than viscosity of the first applied collagen solution.
    Type: Grant
    Filed: December 13, 2013
    Date of Patent: June 27, 2017
    Assignee: TOYO BOSEKI KABUSHIKI KAISHA
    Inventors: Fumihiko Kajii, Hidenori Tanaka, Yuta Kawakatsu, Susumu Kashiwabara, Masaki Sato
  • Patent number: 9017714
    Abstract: A nerve regeneration-inducing tube is provided which is excellent in cell growth property, resistance to pressure, shape recovery property, and anti-kink property in a nerve regeneration-inducing tube where a collagen solution is applied on the outer surface of a tubular body woven with ultrafine fiber comprising biodegradable and bioabsorbable polymer while collagen is filled in the inner area of the tubular body. The nerve regeneration-inducing tube has a degradation speed which is adjusted so as to make it suitable for the connection of nerve gaps of more than 40 mm. The nerve regeneration-inducing tube includes collagen coated on the outer surface of a tubular body woven with fiber bundles where plural ultrafine fibers comprising a biodegradable and bioabsorbable polymer are bundled. The tubular body mostly comprises a first polymer which is biodegradable and bioabsorbable and a second polymer which has higher biodegradability and bioabsorbability than those of the first polymer.
    Type: Grant
    Filed: December 25, 2008
    Date of Patent: April 28, 2015
    Assignee: Toyo Boseki Kabushiki Kaisha
    Inventors: Fumihiko Kajii, Hidenori Tanaka, Susumu Kashiwabara, Yuta Kawakatsu
  • Patent number: 8916225
    Abstract: The present invention provides a method for coating an inner surface of a polyvinyl chloride medical tube containing a plasticizer with an antithrombogenic material composed of a specific (meth)acrylate copolymer. The simple method of the present invention is capable of evenly and efficiently coating an inner surface of a polyvinyl chloride medical tube with a sufficient amount of an antithrombogenic material without causing appearance deterioration or uneven coating due to elution of the plasticizer. The method is performed by passing through a tube a solution that is prepared by dissolving an antithrombogenic material in a solvent composed of water and at least one alcohol that is adjusted to dissolve the copolymer of the antithrombogenic material but does not dissolve the plasticizer, then subsequently passing water through the tube, and finally drying the tube.
    Type: Grant
    Filed: January 6, 2011
    Date of Patent: December 23, 2014
    Assignee: Toyo Boseki Kabushiki Kaisha
    Inventors: Fumihiko Kajii, Hidenori Tanaka, Susumu Kashiwabara
  • Patent number: 8741328
    Abstract: The present invention provides a nerve regeneration-inducing tube in which collagen having excellent adhesive property, cell growth property and differentiation inducing property to nerve cells is used as a scaffold for the nerve regeneration. The nerve regeneration-inducing tube is characterized in using the collagen which is made the concentration of sodium chloride contained therein not more than 2.0% by weight or, preferably, 0.1 to 1.5% by weight in a dry state. Purification of collagen is carried out by means of an isoelectric precipitation where the pH is 6.0 or higher and is lower than 10.0.
    Type: Grant
    Filed: February 2, 2009
    Date of Patent: June 3, 2014
    Assignee: Toyo Boseki Kabushiki Kaisha
    Inventors: Michiko Suzuki, Fumihiko Kajii, Hidenori Tanaka, Susumu Kashiwabara
  • Publication number: 20140100591
    Abstract: A method for manufacturing a nerve regeneration-inducing tube with excellent pressure resistance, shape recovery property, anti-kink property, film exfoliation resistance, resistance to invasion of outer tissues, and leakage resistance. The tubular body is formed by weaving together fibers made up of biodegradable polymer. The outer surface of the tubular body is coated multiple times with a collagen solution. The lumen of the tubular body is filled with collagen. Viscosity of the collagen solution that is first applied to the outer surface of the tubular body is between 2 to 800 cps. Viscosity of the collagen solution that is subsequently applied is higher than viscosity of the first applied collagen solution.
    Type: Application
    Filed: December 13, 2013
    Publication date: April 10, 2014
    Applicant: TOYO BOSEKI KABUSHIKI KAISHA
    Inventors: Fumihiko Kajii, Hidenori Tanaka, Yuta Kawakatsu, Susumu Kashiwabara, Masaki Sato
  • Publication number: 20140099427
    Abstract: A method for manufacturing a nerve regeneration-inducing tube with excellent pressure resistance, shape recovery property, anti-kink property, film exfoliation resistance, resistance to invasion of outer tissues, and leakage resistance. The tubular body is formed by weaving together fibers made up of biodegradable polymer. The outer surface of the tubular body is coated multiple times with a collagen solution. The lumen of the tubular body is filled with collagen. Viscosity of the collagen solution that is first applied to the outer surface of the tubular body is between 2 to 800 cps. Viscosity of the collagen solution that is subsequently applied is higher than viscosity of the first applied collagen solution.
    Type: Application
    Filed: December 13, 2013
    Publication date: April 10, 2014
    Applicant: TOYO BOSEKI KABUSHIKI KAISHA
    Inventors: Fumihiko Kajii, Hidenori Tanaka, Yuta Kawakatsu, Susumu Kashiwabara, Masaki Sato
  • Patent number: 8632844
    Abstract: A method for manufacturing a nerve regeneration-inducing tube with excellent pressure resistance, shape recovery property, anti-kink property, film exfoliation resistance, resistance to invasion of outer tissues, and leakage resistance. The tubular body is formed by weaving together fibers made up of biodegradable polymer. The outer surface of the tubular body is coated multiple times with a collagen solution. The lumen of the tubular body is filled with collagen. Viscosity of the collagen solution that is first applied to the outer surface of the tubular body is between 2 to 800 cps. Viscosity of the collagen solution that is subsequently applied is higher than viscosity of the first applied collagen solution.
    Type: Grant
    Filed: December 4, 2008
    Date of Patent: January 21, 2014
    Assignee: Toyo Boseki Kabushiki Kaisha
    Inventors: Fumihiko Kajii, Hidenori Tanaka, Yuta Kawakatsu, Susumu Kashiwabara, Masaki Sato
  • Publication number: 20120283665
    Abstract: The present invention provides a method for coating an inner surface of a polyvinyl chloride medical tube containing a plasticizer with an antithrombogenic material composed of a specific (meth)acrylate copolymer. The simple method of the present invention is capable of evenly and efficiently coating an inner surface of a polyvinyl chloride medical tube with a sufficient amount of an antithrombogenic material without causing appearance deterioration or uneven coating due to elution of the plasticizer. The method is performed by passing through a tube a solution that is prepared by dissolving an antithrombogenic material in a solvent composed of water and at least one alcohol that is adjusted to dissolve the copolymer of the antithrombogenic material but does not dissolve the plasticizer, then subsequently passing water through the tube, and finally drying the tube.
    Type: Application
    Filed: January 6, 2011
    Publication date: November 8, 2012
    Applicant: TOYO BOSEKI KABUSHIKI KAISHA
    Inventors: Fumihiko Kajii, Hidenori Tanaka, Susumu Kashiwabara
  • Publication number: 20110288569
    Abstract: The present invention provides a nerve regeneration-inducing tube in which collagen having excellent adhesive property, cell growth property and differentiation inducing property to nerve cells is used as a scaffold for the nerve regeneration. The nerve regeneration-inducing tube is characterized in using the collagen which is made the concentration of sodium chloride contained therein not more than 2.0% by weight or, preferably, 0.1 to 1.5% by weight in a dry state. Purification of collagen is carried out by means of an isoelectric precipitation where the pH is 6.0 or higher and is lower than 10.0.
    Type: Application
    Filed: February 2, 2009
    Publication date: November 24, 2011
    Applicant: TOYO BOSEKI KABUSHIKI KAISHA
    Inventors: Michiko Suzuki, Fumihiko Kajii, Hidenori Tanaka, Susumu Kashiwabara
  • Publication number: 20100255060
    Abstract: To provide a nerve regeneration-inducing tube being excellent in cell growth property, resistance to pressure, shape recovery property, and anti-kink property in a nerve regeneration-inducing tube where a collagen solution is applied on the outer surface of a tubular body knitted with ultrafine fiber comprising biodegradable and bioabsorbable polymer while collagen is filled in the inner area of the tubular body. Specifically, to provide a nerve regeneration-inducing tube where a degradation speed is adjusted so as to make it suitable for the connection of nerve gaps of more than 40 mm.
    Type: Application
    Filed: December 25, 2008
    Publication date: October 7, 2010
    Applicant: TOYO BOSEKI KABUSHIKI KAISHA
    Inventors: Fumihiko Kajii, Hidenori Tanaka, Susumu Kashiwabara, Yuta Kawakatsu
  • Publication number: 20100249811
    Abstract: To provide a method for the manufacture of a nerve regeneration-inducing tube being excellent in pressure resistance, shape recovery property, anti-kink property, film exfoliation resistance, property of prevention of invasion of outer tissues and leakage resistance. The present invention is a method for the manufacture of a nerve regeneration-inducting tube in which the outer surface of the tubular body knitted with a plurality of ultrafine fibers comprising biodegradable polymer is coated by application of a collagen solution for plural times to coat and then collagen is filled in the inner area of the above tubular body, characterized in that, viscosity of the collagen solution which is firstly applied on the outer surface of the tubular body is made 2 cps to 800 cps or, preferably, 5 cps to 200 cps. Preferably, viscosity of a collagen solution to be applied later is made high as compared with that of the firstly-applied one.
    Type: Application
    Filed: December 4, 2008
    Publication date: September 30, 2010
    Applicant: TOYO BOSEKI KABUSHIKI KAISHA
    Inventors: Fumihiko Kajii, Hidenori Tanaka, Yuta Kawakatsu, Susumu Kashiwabara, Masaki Sato