Abstract: A drug management device includes a first acquisition unit configured to acquire prescription data including data indicative of a drug prescribed to a subject, a second acquisition unit configured to acquire biometric data including data indicative of variations in a physical quantity of a living body of the subject, a first estimation unit configured to estimate, on the basis of the data indicative of variations in the physical quantity, whether or not the subject has taken the drug, and a second estimation unit configured to, in response to an estimation result indicating that the subject has taken the drug, estimate, on the basis of the data indicative of variations in the physical quantity, whether or not an effect of the drug on the subject satisfies an effect estimation criterion, which is predetermined.

Abstract: Disclosed is a mass spectrometer capable of highly sensitively and highly efficiently measuring the masses of ions regardless of the polarity, mass numbers and energy of the ions. An ion beam transport unit (5), a conversion dynode (6) and a secondary electron detecting system (7) are disposed so that an acute angle is formed between the direction of travel of an ion beam striking on the conversion dynode (6), and a line (75) connecting the center (64) of a secondary electron exit (63) to the center (73) of a scintillator (71). The center axis (74) of the scintillator (71) lies between an end (52) of the ion transport unit (5) and the center axis (64) of the secondary electron exit (63). Since the secondary electron exit (63) is apart from an electric field created between the ion transport unit (5) and the scintillator (71), the secondary electrons are able to reach the scintillator (71) without being deflected.

Abstract: A mass spectrometric apparatus is disclosed which has quadrupole electrodes to which a DC voltage and a high-frequency voltage are applied in a superposed manner, and measures a mass spectrum by scanning particular mass numbers of ions passing through respective stable regions by changing the DC voltage and the high-frequency voltage in very small steps every predetermined time interval step while keeping a relationship in magnitude between the DC voltage and the high-frequency voltage in the stable regions which provide stable trajectories of the ions of the respective mass numbers.

Abstract: An atmospheric pressure ionization type mass spectrometer comprises an ionization section opened to the atmosphere including a desolvation chamber, an ionization chamber, and a corona discharge needle for ionizing sample, a mass analysis section including a mass spectrometry, an intermediate pressure section in which cluster ions of the sample are accelerated by a drift voltage from the ionization section towards the mass analysis section. In advance of the mass spectroscopy, the moisture in the atmosphere is ionized into the water cluster ions. Such water cluster ions are used for calibrating a mass marker of the mass spectrometry.