Patents by Inventor Fumihiko Toriyama

Fumihiko Toriyama has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for Producing Diarylpyridine Derivatives
    Publication number: 20210188823
    Abstract: The present invention relates to a novel method for producing diarylpyridine derivatives, and the object of the present invention is to provide a novel, industrially useful method. The present inventors developed a novel method for synthesizing pyridine rings without using palladium, a strong base, or a high-temperature reaction. In particular, they successfully developed a method that can be used to synthesize iminium salts as intermediates, synthesize cyano compounds from these iminium salts, and cyclize the cyano compounds into pyridines under very mild reaction conditions.
    Type: Application
    Filed: July 3, 2019
    Publication date: June 24, 2021
    Inventors: Yuichi Aki, Fumihiko Toriyama, Natsuki Sakurai, Ai Kameda, Tomokazu Ogura
  • Method for Manufacturing Neuraminic Acid Derivatives
    Publication number: 20170114035
    Abstract: The present invention provides methods for manufacturing neuraminic acid derivatives. [Means for solution] Methods for manufacturing compounds represented by the formula (I): [wherein R1 represents a C1-C19 alkyl group], or a pharmacologically acceptable salt thereof, using N-acetylneuraminic acid dihydrate as a starting raw material are provided.
    Type: Application
    Filed: January 9, 2017
    Publication date: April 27, 2017
    Inventors: Tomohito SAKURAI, Takumi NAKAJIMA, Masakazu WAKAYAMA, Fumihiko TORIYAMA, Yasuhisa KUWAHARA
  • Method for Manufacturing Neuraminic Acid Derivatives
    Publication number: 20140356625
    Abstract: The present invention provides methods for manufacturing neuraminic acid derivatives. [Means for solution] Methods for manufacturing compounds represented by the formula (I): [wherein R1 represents a C1-C19 alkyl group], or a pharmacologically acceptable salt thereof, using N-acetylneuraminic acid dihydrate as a starting raw material are provided.
    Type: Application
    Filed: December 13, 2012
    Publication date: December 4, 2014
    Inventors: Tomohito Sakurai, Takumi Nakajima, Masakazu Wakayama, Fumihiko Toriyama, Yasuhisa Kuwahara
  • Process for producing cyclic thioether and synthetic intermediate thereof
    Patent number: 7396930
    Abstract: A process for producing cyclic thioether compounds and their synthetic intermediates. The process produces a compound represented by formula (5): wherein G1 is an alkylene group, R1 is a thiol protecting group, R2 is hydrogen or an amino protecting group, and Ar is an aryl group or a 5- to 7-membered heteroaryl group.
    Type: Grant
    Filed: December 6, 2004
    Date of Patent: July 8, 2008
    Assignee: Sankyo Company, Limited
    Inventors: Hiroshi Tomori, Keijiro Kobayashi, Fumihiko Toriyama
  • Process for producing cyclic thioether and synthetic intermediate thereof
    Publication number: 20050165037
    Abstract: A process for producing cyclic thioether compounds and their synthetic intermediates. The process produces a compound represented by formula (5): wherein G1 is an alkylene group, R1 is a thiol protecting group, R2 is hydrogen or an amino protecting group, and Ar is an aryl group or a 5- to 7-membered heteroaryl group.
    Type: Application
    Filed: December 6, 2004
    Publication date: July 28, 2005
    Applicant: SANKYO COMPANY, LIMITED
    Inventors: Hiroshi Tomori, Keijiro Kobayashi, Fumihiko Toriyama