Patents by Inventor Fumikazu Takahashi

Fumikazu Takahashi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10378011
    Abstract: An oligonucleotide having improved affinity for AGO2 is disclosed. The oligonucleotide has a nucleotide residue or a nucleoside residue represented by formula (I) wherein X1 is an oxygen atom or the like, R1 is formula (IIA), wherein R5A is halogen or the like, and R6A is a hydrogen atom or the like, or formula (IVA) wherein Y3A is a nitrogen atom or the like, and Y4A is CH or the like, or the like, R2 is a hydrogen atom, hydroxy, halogen, or optionally substituted lower alkoxy, and R3 is a hydrogen atom or the like at the 5? end thereof, and the nucleotide residue or the nucleoside residue binds to an adjacent nucleotide residue through the oxygen atom at position 3. A method for improving the knockdown activity of an oligonucleotide wherein the oligonucleotide has a knockdown activity against an mRNA encoding a protein involved in a disease.
    Type: Grant
    Filed: September 2, 2013
    Date of Patent: August 13, 2019
    Assignee: KYOWA HAKKO KIRIN CO., LTD.
    Inventors: Fumikazu Shinohara, Asana Makino, Junichiro Yamamoto, Taiji Oashi, Michihiko Suzuki, Jun-ichi Saito, Takahiro Nakajima, Tomoyuki Nishikawa, Masayoshi Nakoji, Yuichi Takahashi
  • Patent number: 10351862
    Abstract: Provided is a promoter suitable for the high expression of a gene of interest. A promoter consisting of a DNA selected from the group consisting of the following (a) to (d): (a) a DNA comprising the nucleotide sequence represented by any one of SEQ ID NOs: 1 to 3; (b) a DNA consisting of a nucleotide sequence having at least 70% identity to the nucleotide sequence represented by any one of SEQ ID NOs: 1 to 3 and having a promoter activity; (c) a DNA consisting of a nucleotide sequence wherein one or several of nucleotides are deleted, substituted or added in the nucleotide sequence represented by any one of SEQ ID NOS: 1 to 3 and having a promoter activity; and (d) a DNA which hybridizes with a DNA consisting of a nucleotide sequence complementary to the nucleotide sequence represented by any one of SEQ ID NOs: 1 to 3 under stringent conditions and which has a promoter activity.
    Type: Grant
    Filed: July 27, 2016
    Date of Patent: July 16, 2019
    Assignee: Kao Corporation
    Inventors: Jitsuro Kaneda, Yuichi Tsuboi, Fumikazu Takahashi
  • Patent number: 10342819
    Abstract: An oligonucleotide having a nucleotide residue or a nucleoside residue represented by formula (I) {wherein X1 is an oxygen atom or the like, R1 is formula (IIA) (wherein R5A is halogen or the like, and R6A is a hydrogen atom or the like), formula (IVA) (wherein Y3A is a nitrogen atom or the like, and Y4A is CH or the like), or the like, R2 is a hydrogen atom, hydroxy, halogen, or optionally substituted lower alkoxy, and R3 is a hydrogen atom or the like, or formula (VI) (wherein n2 is 1, 2 or 3)} at the 5? end thereof, wherein the nucleotide residue or the nucleoside residue binds to an adjacent nucleotide residue through the oxygen atom at position 3, is provided.
    Type: Grant
    Filed: March 3, 2015
    Date of Patent: July 9, 2019
    Assignee: KYOWA HAKKO KIRIN CO., LTD.
    Inventors: Fumikazu Shinohara, Asana Makino, Junichiro Yamamoto, Takahiro Nakajima, Taiji Oashi, Michihiko Suzuki, Jun-ichi Saito, Tomoyuki Nishikawa, Masayoshi Nakoji, Yuichi Takahashi, Yasuo Kouda
  • Publication number: 20190186018
    Abstract: A grain-oriented electrical steel sheet according to one embodiment of the present invention includes a steel sheet and an insulation coating, in which the insulation coating contains a first metal phosphate, which is a metal phosphate of one or two more metals selected from Al, Fe, Mg, Mn, Ni, and Zn; a second metal phosphate, which is a metal phosphate of one or two more metals selected from Co, Mo, V, W, and Zr; and colloidal silica, the insulation coating does not contain chromate, and an elution amount of phosphoric acid of the insulation coating as determined by boiling the grain-oriented electrical steel sheet in a boiled pure water for 10 minutes, then measuring an elution amount of phosphoric acid into the pure water, and dividing the amount of phosphoric acid by the area of the insulation coating of the boiled grain-oriented electrical steel sheet is 30 mg/m2 or less.
    Type: Application
    Filed: September 28, 2016
    Publication date: June 20, 2019
    Applicant: NIPPON STEEL & SUMITOMO METAL CORPORATION
    Inventors: Kazutoshi TAKEDA, Fumikazu ANDOU, Tomoya SUENAGA, Shuichi YAMAZAKI, Masaru TAKAHASHI
  • Publication number: 20190062723
    Abstract: Provided is a microorganism exhibiting high production capability for sophorolipids. Disclosed is a yeast mutant strain having high sophorolipid productivity, in which a transporter transporting Acyl-CoA to a peroxisome has been deleted or deactivated.
    Type: Application
    Filed: July 15, 2016
    Publication date: February 28, 2019
    Applicant: KAO CORPORATION
    Inventors: Takahiro ICHIHARA, Masatoshi TOHATA, Atsuko HAYASE, Fumikazu TAKAHASHI
  • Patent number: 10063058
    Abstract: A power converter includes a plurality of converters which are connected in parallel to a DC power supply in which an operating point is changed in accordance with an output current or an output voltage. The plurality of converters include maximum power point tracking units for performing maximum power point tracking calculations of the DC power supply. Results of the maximum power point tracking calculations of the plurality of converters are unified between the plurality of converters and the plurality of converters are controlled based on the unified calculation result.
    Type: Grant
    Filed: March 13, 2017
    Date of Patent: August 28, 2018
    Assignee: Hitachi Information & Telecommunication Engineering, Ltd.
    Inventors: Takae Shimada, Fumikazu Takahashi, Kimiaki Taniguchi, Kosuke Abe
  • Publication number: 20180223292
    Abstract: Provided is a promoter suitable for the high expression of a gene of interest. A promoter consisting of a DNA selected from the group consisting of the following (a) to (d): (a) a DNA comprising the nucleotide sequence represented by any one of SEQ ID NOs: 1 to 3; (b) a DNA consisting of a nucleotide sequence having at least 70% identity to the nucleotide sequence represented by any one of SEQ ID NOs: 1 to 3 and having a promoter activity; (c) a DNA consisting of a nucleotide sequence wherein one or several of nucleotides are deleted, substituted or added in the nucleotide sequence represented by any one of SEQ ID NOS: 1 to 3 and having a promoter activity; and (d) a DNA which hybridizes with a DNA consisting of a nucleotide sequence complementary to the nucleotide sequence represented by any one of SEQ ID NOs: 1 to 3 under stringent conditions and which has a promoter activity.
    Type: Application
    Filed: July 27, 2016
    Publication date: August 9, 2018
    Applicant: Kao Corporation
    Inventors: Jitsuro KANEDA, Yuichi TSUBOI, Fumikazu TAKAHASHI
  • Publication number: 20180208935
    Abstract: Provided is a microorganism having high sophorolipid production capability. Disclosed is a sophorolipid-producing yeast mutant strain, in which a polypeptide consisting of the amino acid sequence set forth in SEQ ID NO:2 or an amino acid sequence having at least 90% identity therewith, has been deleted or deactivated.
    Type: Application
    Filed: July 15, 2016
    Publication date: July 26, 2018
    Applicant: Kao Corporation
    Inventors: Takahiro ICHIHARA, Yasushi KAGEYAMA, Masatoshi TOHATA, Fumikazu TAKAHASHI
  • Patent number: 9991819
    Abstract: A power conversion system is capable of distinguishing easily and clearly between being interconnected to the power system and being in an isolated operation. The power conversion system converts DC power to AC power to interconnect with a power system and injects reactive power into a grid node for determining an isolated operation, including: a voltage detector that detects an output voltage at the grid node; a current detector that detects an output current at the grid node; a frequency measurement unit that measures a frequency of the output voltage at the grid node; a reactive-power measurement unit that measures reactive power at the grid node; and an isolated-operation determination unit that determines whether or not the power conversion system is in an isolated operation as disconnected from the power system. The isolated-operation determination unit includes a reactive-power-fluctuation determination unit that performs a first isolated-operation determination from the reactive power.
    Type: Grant
    Filed: October 21, 2014
    Date of Patent: June 5, 2018
    Assignee: Hitachi Information & Telecommunication Engineering, Ltd.
    Inventors: Tomoyuki Hatakeyama, Akira Kikuchi, Fumikazu Takahashi, Kimiaki Taniguchi, Hirofumi Oyamada
  • Publication number: 20170279279
    Abstract: A power converter includes a plurality of converters which are connected in parallel to a DC power supply in which an operating point is changed in accordance with an output current or an output voltage. The plurality of converters include maximum power point tracking units for performing maximum power point tracking calculations of the DC power supply. Results of the maximum power point tracking calculations of the plurality of converters are unified between the plurality of converters and the plurality of converters are controlled based on the unified calculation result.
    Type: Application
    Filed: March 13, 2017
    Publication date: September 28, 2017
    Inventors: Takae SHIMADA, Fumikazu TAKAHASHI, Kimiaki TANIGUCHI, Kosuke ABE
  • Patent number: 9680303
    Abstract: A power storage system is provided with charge switches, discharge switches, a bidirectional DC/DC converter and a power storage system controller connecting all the battery packs to an external circuit to achieve parallel charge and discharge, and the power storage system starts the charge by setting a rated charge current value per one battery pack to Iset and setting the rated charge current value Iset as an initial value of a charge current command value Iref(1), thereafter monitor the charge current of each of the battery packs after elapse of a predetermined time so as to subtract its maximum value Ibmax(1) from the charge current command value Iref(1), and add the rated charge current value Iset to result of subtraction Ierr (Iref(1)?Ibmax(1)) so as to set as a new charge current command value Iref(2) and carry out pre-charge in such a manner as to carry on the charge.
    Type: Grant
    Filed: October 24, 2013
    Date of Patent: June 13, 2017
    Assignee: Hitachi Information & Telecommunication Engineering, Ltd.
    Inventors: Fumikazu Takahashi, Yoshihide Takahashi, Yusuke Katsuyama, Kimiaki Taniguchi, Akinori Uchida, Masahiro Hamaogi, Susumu Nagafuchi
  • Publication number: 20170155325
    Abstract: A resonant power supply includes a full bridge circuit having a first switching leg and a second switching leg and a control unit that controls operations of a first upper arm switching device and a first lower arm switching device constituting the first switching leg, and a second upper arm switching device and a second lower arm switching device constituting the second switching leg and feeds power to a load from a DC power supply via the full bridge circuit. The control unit controls the full bridge circuit so as to have a phase difference between a turn-off of the first upper arm switching device and the turn-off of the second lower arm switching device, and increases the phase difference in accordance with increase of a switching frequency of the full bridge circuit.
    Type: Application
    Filed: November 9, 2016
    Publication date: June 1, 2017
    Inventors: Takae SHIMADA, Yuki KAWAGUCHI, Fumikazu TAKAHASHI, Kimiaki TANIGUCHI, Kosuke ABE
  • Patent number: 9540672
    Abstract: A protein selected from the following (a) to (c), a gene encoding the protein, a transformant in which the gene is subjected to deletion, mutation or repression of gene expression, and a method of producing a glycolipid using the transformant are provided, wherein: (a) is a protein consisting of an amino acid sequence set forth in SEQ ID NO: 1; (b) is a protein consisting of an amino acid sequence having 50% or more identity with the amino acid sequence set forth in SEQ ID NO: 1, and having alcohol oxidase activity; and (c) is a protein consisting of an amino acid sequence in which one to several amino acids are subjected to deletion, substitution, insertion or addition in the amino acid sequence set forth in SEQ ID NO: 1, and having alcohol oxidase activity.
    Type: Grant
    Filed: October 3, 2013
    Date of Patent: January 10, 2017
    Assignee: Kao Corporation
    Inventor: Fumikazu Takahashi
  • Patent number: 9515557
    Abstract: In a step-up step-down converter device, a diode is connected in parallel to a switch connecting a positive pole side and a negative pole side for stepping up and stepping down an input voltage, a diode is connected in parallel to a switch in a positive pole side of a closed circuit constructed between an input direct voltage and an output side load, and a control circuit detecting an output voltage generates 1st Phase PWM and 2nd Phase PWM obtained by logically adding and multiplying two difference values having phase difference in comparison with a triangle waveform signal which is 180 degrees different in phase from an error signal based on a difference value between the output voltage and a target reference voltage, and alternately turns on and off switches respectively by using 1st Phase PWM or 2nd Phase PWM at the step-down or step-down operation time.
    Type: Grant
    Filed: March 4, 2015
    Date of Patent: December 6, 2016
    Assignee: HITACHI INFORMATION & TELECOMMUNICATION ENG., LTD.
    Inventors: Kosuke Abe, Fumikazu Takahashi
  • Patent number: 9306472
    Abstract: A power supply device of the invention includes a first switching leg including first and second switching elements between DC terminals; a second switching leg including third and fourth switching elements between the DC terminals; a first capacitor leg including first and second capacitors between the DC terminals; a second capacitor leg including third and fourth capacitors between AC terminals; a first inductor between a connection of the first and second switching elements and one of the AC terminals; a second inductor between a connection of the third and fourth switching elements and another of the AC terminals; a controller; an AC power supply connected to the AC terminals and the connection of the third and fourth capacitors; and a DC power supply between the DC terminals, wherein the controller charges the first and second capacitors to a voltage higher than a voltage crest of the AC power supply.
    Type: Grant
    Filed: July 25, 2014
    Date of Patent: April 5, 2016
    Assignee: HITACHI INFORMATION & TELECOMMUNICATION ENGINEERING, LTD.
    Inventors: Takae Shimada, Akihiko Kanouda, Fumikazu Takahashi, Nobuyuki Aihara
  • Patent number: 9222111
    Abstract: To provide a method for supplying lauric acid with algae. A method for producing an oil or fat containing lauric acid as a constituent fatty acid including: culturing, in a medium, at least one species of algae in the class Cryptophyceae selected from the group consisting of algae belonging to the genus Rhodomonas and algae belonging to the genus Chroomonas selected from among Chroomonas diplococca, Chroomonas mesostigmatica, Chroomonas nordstedtii, and Chroomonas placoidea and recovering, from the culture product, an oil or fat having a lauric acid content of 3 weight % or higher of the fatty acid composition.
    Type: Grant
    Filed: March 24, 2011
    Date of Patent: December 29, 2015
    Assignee: Kao Corporation
    Inventors: Hiroshi Yoshida, Fumikazu Takahashi, Yasushi Takimura
  • Patent number: 9225181
    Abstract: A power storage system is provided with a battery and a battery charger which charges a battery pack having a battery voltage and current detection circuit. A charge circuit is structured such as to acquire terminal voltage information of the battery from a battery voltage detection circuit of the battery pack in a charging process, carry out a constant current charge control in a state in which the terminal voltage of the battery is equal to or lower than a previously determined reference voltage value of the battery, and switch to a constant voltage charge control maintaining the output voltage of the charge circuit in the case that the terminal voltage of the battery goes beyond the reference voltage value, thereby carrying on the charge until the battery is fully charged. Therefore, the power storage system can accurately charge the battery to a prescribed amount safely.
    Type: Grant
    Filed: October 24, 2013
    Date of Patent: December 29, 2015
    Assignee: Hitachi Information & Telecommunication Engineering, Ltd.
    Inventors: Kimiaki Taniguchi, Fumikazu Takahashi, Yusuke Katsuyama, Yoshihide Takahashi, Daisuke Ishida, Akinori Uchida, Susumu Nagafuchi
  • Publication number: 20150303731
    Abstract: In relation to an electric energy storage device or others, a configuration of efficient power feeding means to a control circuit is achieved. A storage device of a present embodiment includes a storage battery; an input/output terminal connectable to a power supply; a power converting device between the storage battery and the terminal; a control unit including a control circuit to controls charge/discharge of the storage battery; a first DC/DC converter connected to a first node between the storage battery and the power converting device and which outputs a first voltage; a second DC/DC converter connected to a second node inside the power converting device and which outputs a second voltage; a first diode connected between the first DC/DC converter and the control circuit; and a second diode connected between the second DC/DC converter and the control circuit. The first voltage and the second voltage are different from each other.
    Type: Application
    Filed: December 28, 2012
    Publication date: October 22, 2015
    Inventors: Fumikazu Takahashi, Kimiaki Taniguchi, Shouichi Hirota
  • Publication number: 20150267235
    Abstract: A protein selected from the following (a) to (c), a gene encoding the protein, a transformant in which the gene is subjected to deletion, mutation or repression of gene expression, and a method of producing a glycolipid using the transformant: (a) A protein consisting of an amino acid sequence set forth in SEQ ID NO: 1; (b) A protein consisting of an amino acid sequence having 50% or more identity with the amino acid sequence set forth in SEQ ID NO: 1, and having alcohol oxidase activity; and (c) A protein consisting of an amino acid sequence in which one to several amino acids are subjected to deletion, substitution, insertion or addition in the amino acid sequence set forth in SEQ ID NO: 1, and having alcohol oxidase activity.
    Type: Application
    Filed: October 3, 2013
    Publication date: September 24, 2015
    Applicant: Kao Corporation
    Inventor: Fumikazu Takahashi
  • Publication number: 20150263608
    Abstract: In a step-up step-down converter device, a diode is connected in parallel to a switch connecting a positive pole side and a negative pole side for stepping up and stepping down an input voltage, a diode is connected in parallel to a switch in a positive pole side of a closed circuit constructed between an input direct voltage and an output side load, and a control circuit detecting an output voltage generates 1st Phase PWM and 2nd Phase PWM obtained by logically adding and multiplying tow difference values having phase difference in comparison with a triangle waveform signal which is 180 degrees different in phase from an error signal based on a difference value between the output voltage and a target reference voltage, and alternately turns on and off switches respectively by using 1st Phase PWM or 2nd Phase PWM at the step-down or step-down operation time.
    Type: Application
    Filed: March 4, 2015
    Publication date: September 17, 2015
    Inventors: KOSUKE ABE, Fumikazu Takahashi