Patents by Inventor Fumiko Oogaki

Fumiko Oogaki has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Monoclonal antibody
    Patent number: 5658742
    Abstract: This invention relates to a monoclonal antibody having affinity to human TCF-II without any affinity to HGF and determination or purification methods of TCF-II using the antibody. The monoclonal antibody can be obtained by adding a blocking solution containing a surface active agent to the culture medium containing monoclonal antibody to block antibodies other than said monoclonal antibody, followed by reaction with a solid phase antigen, TCF-II. Human TCF-II can be selectively and effectively purified or determined without any influence of the presence of HGF by using the antibody.
    Type: Grant
    Filed: March 15, 1995
    Date of Patent: August 19, 1997
    Assignee: Snow Brand Milk Products Co., Ltd.
    Inventors: Kanji Higashio, Nobuyuki Shima, Fumiko Oogaki
  • Modified tumor cytotoxic factor (TCF) and DNA encoding such
    Patent number: 5648233
    Abstract: Modified TCF in which one or more amino-acid residues of the wild type TCF responsible for glycosylation are substituted or deleted so that at least one N-linked oligosaccharide chain is removed. The modified TCFs have a longer biological half-lives without loss of their biological activities. The modified TCFs are therapeutically important as agents for liver diseases or as anti-cancer drugs.
    Type: Grant
    Filed: September 29, 1994
    Date of Patent: July 15, 1997
    Assignee: Snow Brand Milk Products Co., Ltd.
    Inventors: Kyoji Yamaguchi, Nobuyuki Shima, Akihiko Murakami, Masaaki Goto, Eisuke Tsuda, Hiroaki Masunaga, Reiko Takahira, Fumiko Oogaki, Masatsugu Ueda, Kanji Higashio
  • Plasmids containing DNA encoding the amino acid sequence of TCF-II and use thereof
    Patent number: 5328836
    Abstract: Plasmids containing DNA encoding the amino acid sequence of a novel glycoprotein (TCF-II) derived from human fibroblasts, transformed cells with the plasmids and production method of rTCF-II using the transformed cells. rTCF-II can be used as a hepatocyte growth factor or a tumor cytotoxic factor.
    Type: Grant
    Filed: March 11, 1992
    Date of Patent: July 12, 1994
    Assignee: Snow Brand Milk Products Co., Ltd.
    Inventors: Nobuyuki Shima, Kanji Higashio, Masaya Nagao, Fumiko Oogaki, Hiroaki Takaoka, Eisuke Tsuda