Abstract: The present invention provides a shielding member for radioactive substances which can be made compact in size and light in weight while maintaining its shielding ability, or improves the shielding ability while keeping the same size, thereby to store a large volume of radioactivity. At the same time, the present invention provides a manufacturing method for the above shielding member and a radioactive solution-producing apparatus using the above shielding member. The radioactive substance-shielding member uses two or more kinds of radiation shielding materials of different shielding abilities. A shielding body made of a shielding material of the highest shielding ability is arranged at an area which is the nearest to a radioactive source.

Abstract: We have found a novel subtype DRw14c and sequenced the nucleotide sequence thereof. DRw14 associated genes can be genetically typed at the DNA level using DRB1-14c sequence specific oligonucleotide probes such as F142 and F144 of the invention. The present invention overcomes the disadvantages of serological typing and provides a reagent that determines a type of a HLA-DR antigen. More specifically, the invention provides an oligonucleotide probe capable of identifying subtypes of a HLA-DR antigen precisely and a reagent containing the oligonucleotide probe. Furthermore, the invention provides a method of detecting a novel HLA-DR antigen.