Patents by Inventor Fumiya OOHASHI

Fumiya OOHASHI has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20170304504
    Abstract: A method for treating a disease associated with tissue abnormality in a subject. The method includes administering an amount of a pharmaceutical composition to a subject in need of treating a disease associated with tissue abnormality, the pharmaceutical composition comprising a laminate comprising a fibrin gel and a cell culture. The laminate is produced by a method, which includes forming a fibrin gel layer on an upper surface of the cell culture by a reaction between fibrinogen and thrombin, wherein: the cell culture is prepared on a culture dish and the laminate of the fibrin gel and the cell culture are transferred onto a subject's heart. The laminate further includes a reinforcing portion made of a fibrin gel, the reinforcing portion formed by laminating the fibrin gel on the fibrin gel layer of the laminate of the cell culture and the fibrin gel.
    Type: Application
    Filed: July 12, 2017
    Publication date: October 26, 2017
    Applicants: TERUMO KABUSHIKI KAISHA, OSAKA UNIVERSITY
    Inventors: Fumiya OOHASHI, Ryouhei TAKEUCHI, Tadashi SAMESHIMA, Shigeru MIYAGAWA, Yoshiki SAWA, Atsuhiro SAITO
  • Patent number: 9737636
    Abstract: A laminate of a sheet-shaped cell culture is disclosed, which has excellent operability and is suitable for implantation. A method is disclosed for producing a laminate of a fibrin gel and a sheet-shaped cell culture, including a step of dripping a liquid containing fibrinogen onto an upper surface of a sheet-shaped cell culture, a step of spraying a liquid containing thrombin onto the surface, and a step of forming a fibrin gel layer on the surface by a reaction between fibrinogen and thrombin; and a laminate of a fibrin gel and a sheet-shaped cell culture produced by the method are disclosed.
    Type: Grant
    Filed: September 3, 2015
    Date of Patent: August 22, 2017
    Assignees: TERUMO KABUSHIKI KAISHA, OSAKA UNIVERSITY
    Inventors: Fumiya Oohashi, Ryouhei Takeuchi, Tadashi Sameshima, Shigeru Miyagawa, Yoshiki Sawa, Atsuhiro Saito
  • Publication number: 20160058908
    Abstract: A laminate of a sheet-shaped cell culture is disclosed, which has excellent operability and is suitable for implantation. A method is disclosed for producing a laminate of a fibrin gel and a sheet-shaped cell culture, including a step of dripping a liquid containing fibrinogen onto an upper surface of a sheet-shaped cell culture, a step of spraying a liquid containing thrombin onto the surface, and a step of forming a fibrin gel layer on the surface by a reaction between fibrinogen and thrombin; and a laminate of a fibrin gel and a sheet-shaped cell culture produced by the method are disclosed.
    Type: Application
    Filed: September 3, 2015
    Publication date: March 3, 2016
    Applicants: OSAKA UNIVERSITY, TERUMO KABUSHIKI KAISHA
    Inventors: Fumiya OOHASHI, Ryouhei TAKEUCHI, Tadashi SAMESHIMA, Shigeru MIYAGAWA, Yoshiki SAWA, Mitsuhiro SAITO