Patents by Inventor Fumiyasu Ishikawa
Fumiyasu Ishikawa has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 9788557Abstract: Disclosed is a novel lactic acid bacterium belonging to Lactobacillus plantarum, which has an excellent fermentative ability affording high achievable cell counts even if various vegetable or fruit juices are used as fermentative substrates. The lactic acid bacterium belonging to Lactobacillus plantarum is characterized by the achievable viable cell counts being 108 CFU/ml or more in both cases when 100% juice of grape or of orange is used as fermentative substrate.Type: GrantFiled: March 15, 2011Date of Patent: October 17, 2017Assignee: Kabushiki Kaisha Yakult HonshaInventors: Tohru Iino, Norie Masuoka, Fumiyasu Ishikawa, Koichi Yoshimura, Eiji Hayashida
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Publication number: 20130064928Abstract: Disclosed is a novel lactic acid bacterium belonging to Lactobacillus plantarum, which has an excellent fermentative ability affording high achievable cell counts even if various vegetable or fruit juices are used as fermentative substrates. The lactic acid bacterium belonging to Lactobacillus plantarum is characterized by the achievable viable cell counts being 108 CFU/ml or more in both cases when 100% juice of grape or of orange is used as fermentative substrate.Type: ApplicationFiled: March 15, 2011Publication date: March 14, 2013Applicant: Kabushiki Kaisha Yakult HonshaInventors: Tohru Iino, Norie Masuoka, Fumiyasu Ishikawa, Koichi Yoshimura, Eiji Hayashida
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Patent number: 8058051Abstract: It is intended to provide Bifidobacterium bifidum which has an effect of killing Helicobacter pylori and shows high survivability even in the case of being stored in a fermented milk food or drink under aerobic condition. The Bifidobacterium bifidum has the following characteristics: (1) having an effect of killing Helicobacter pylori; and (2) showing a survival rate of 10% or higher in the case of being stored in a fermented milk drink or food under aerobic condition at 10° C. for 14 days.Type: GrantFiled: July 20, 2006Date of Patent: November 15, 2011Assignee: Kabushiki Kaisha Yakult HonshaInventors: Atsushi Nose, Daisuke Nozaki, Fumiyasu Ishikawa, Susumu Mizusawa, Ryoichi Akahoshi
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Patent number: 7993903Abstract: To provide a bacterium belonging to the genus Bifidobacterium which is excellent in a survival ability in the gastrointestinal tract, has an effect of inhibiting the cholesterol absorption in the intestinal tract, and is excellent in lipid metabolism ameliorating effects including decreasing the blood cholesterol level and the like, and shows a high survival rate after storage, and a cholesterol absorption inhibitor using the same. The invention provides a cholesterol absorption inhibitor containing, as an active ingredient, at least one microorganism selected from Bifidobacterium animalis subsp. animalis YIT 10394, Bifidobacterium animalis subsp. lactis JCM 1253, Bifidobacterium animalis subsp. lactis JCM 7117, and Bifidobacterium pseudolongum subsp. globosum.Type: GrantFiled: September 7, 2006Date of Patent: August 9, 2011Assignee: Kabushiki Kaisha Yakult HonshaInventors: Hiroko Hayakawa, Tohru Iino, Fumiyasu Ishikawa
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Patent number: 7754255Abstract: A bone metabolism improving agent characterized by containing as the active ingredient fermented soybean milk which is obtained by fermenting soybean milk with a lactic acid bacterium or a bifidobacterium. The bone metabolism improving agent is efficacious in treating and preventing diseases in association with lowered bone metabolism such as osteoporosis and, at the same time, satisfies requirements in cost and smooth intake.Type: GrantFiled: June 26, 2007Date of Patent: July 13, 2010Assignee: Kabushiki Kaisha Yakult HonshaInventors: Satoshi Matsubara, Hiroko Hayakawa, Yasuhisa Shimakawa, Mitsuyoshi Kano, Harue Sone, Fumiyasu Ishikawa
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Publication number: 20090252709Abstract: It is intended to provide Bifidobacterium bifidum which has an effect of killing Helicobacter pylori and shows high survivability even in the case of being stored in a fermented milk food or drink under aerobic condition. The Bifidobacterium bifidum has the following characteristics: (1) having an effect of killing Helicobacter pylori; and (2) showing a survival rate of 10% or higher in the case of being stored in a fermented milk drink or food under aerobic condition at 10° C. for 14 days.Type: ApplicationFiled: July 20, 2006Publication date: October 8, 2009Applicant: KABUSHIKI KAISHA YAKULT HONSHAInventors: Atsushi Nose, Daisuke Nozaki, Fumiyasu Ishikawa, Susumu Mizusawa, Ryoichi Akahoshi
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Publication number: 20090170185Abstract: To provide a bacterium belonging to the genus Bifidobacterium which is excellent in a survival ability in the gastrointestinal tract, has an effect of inhibiting the cholesterol absorption in the intestinal tract, and is excellent in lipid metabolism ameliorating effects including decreasing the blood cholesterol level and the like, and shows a high survival rate after storage, and a cholesterol absorption inhibitor using the same. The invention provides a cholesterol absorption inhibitor containing, as an active ingredient, at least one microorganism selected from Bifidobacterium animalis subsp. animalis YIT 10394, Bifidobacterium animalis subsp. lactis JCM 1253, Bifidobacterium animalis subsp. lactis JCM 7117, and Bifidobacterium pseudolongum subsp. globosum.Type: ApplicationFiled: September 7, 2006Publication date: July 2, 2009Applicant: KABUSHIKI KAISHA YAKULT HONSHAInventors: Hiroko Hayakawa, Tohru Iino, Fumiyasu Ishikawa
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Patent number: 7510735Abstract: A Bifidobacterium that is resistant to acid and bile and which retains at least 20% viability after acid and bile treatment. Foods and drinks containing an acid- and bile-resistant Bifidobacterium. Methods for providing viable Bifidobacteria to the intestine after ingestion of a food or drink containing an acid- and bile-resistant Bifidobacterium.Type: GrantFiled: December 21, 2001Date of Patent: March 31, 2009Assignee: Kabushiki Kaisha Yakult HonshaInventors: Yasuhisa Shimakawa, Masaki Serata, Hirokazu Tsuji, Koichiro Sonoike, Akimitsu Takagi, Mika Miura, Fumiyasu Ishikawa
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Publication number: 20070298146Abstract: A bone metabolism improving agent characterized by containing as the active ingredient fermented soybean milk which is obtained by fermenting soybean milk with a lactic acid bacterium or a bifidobacterium. The bone metabolism improving agent is efficacious in treating and preventing diseases in association with lowered bone metabolism such as osteoporosis and, at the same time, satisfies requirements in cost and smooth intake.Type: ApplicationFiled: June 26, 2007Publication date: December 27, 2007Applicant: KABUSHIKI KAISHA YAKULT HONSHAInventors: Satoshi Matsubara, Hiroko Hayakawa, Yasuhisa Shimakawa, Mitsuyoshi Kano, Harue Sone, Fumiyasu Ishikawa
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Publication number: 20040052902Abstract: Provided is a method of assessing the extent to which Bifidobacterium bacteria in a Bifidobacterium-bacteria-containing fermented milk food or drink reach the intestines when the food or drink is orally administered to human beings, which comprises subjecting the fermented milk food or drink to successive treatments with an acid and bile, and measuring the bacterial viability after the treatments.Type: ApplicationFiled: July 31, 2003Publication date: March 18, 2004Inventors: Yasuhisa Shimakawa, Masaki Serata, Hirokazu Tsuji, Koichiro Sonoike, Akimitsu Takagi, Mika Miura, Fumiyasu Ishikawa
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Publication number: 20040013656Abstract: A bone metabolism improving agent characterized by containing as the active ingredient fermented soybean milk which is obtained by fermenting soybean milk with a lactic acid bacterium or a bifidobacterium.Type: ApplicationFiled: April 11, 2003Publication date: January 22, 2004Inventors: Satoshi Matsubara, Hiroko Hayakawa, Yasuhisa Shimakawa, Mitsuyoshi Kano, Harue Sone, Fumiyasu Ishikawa
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Patent number: 6548057Abstract: A Bifidobacterium breve strain provided is showing a viable count of 1×109 cells/ml or more immediately after culturing in a soymilk medium and sustaining a viable count of 1×108 cells/ml or more after storage at 10° C. for 14 days. The strain is preferably Bifidobacterium breve FERM BP-6223, and is used for producing fermented soymilk.Type: GrantFiled: March 6, 2000Date of Patent: April 15, 2003Assignee: Kabushiki Kaisha Yakult HonshaInventors: Yasuhisa Shimakawa, Takashi Morishita, Fumiyasu Ishikawa
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Patent number: 4929548Abstract: A process for producing GIF-2, an antimicrobial peptide, by culturing Bacillus cereus, FERM BP-746, under conditions sufficient to produce GIF-2 and recovering GIF-2 from the culture medium.Type: GrantFiled: December 2, 1987Date of Patent: May 29, 1990Assignee: Kibun Co., Ltd.Inventors: Sachio Wakayama, Fumiyasu Ishikawa, Kunio Oishi
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Patent number: 4771121Abstract: A substance GIF-2 having bacteriostatic activities and a process for producing the same are disclosed.GIF-2 is produced by culturing bacteria capable of producing GIF-2 and belonging to genus Bacillus, and isolating GIF-2 from the culture medium. GIF-2 is presumed to have the following structure: ##STR1## wherein one of three X's is an amido bond and R is a .beta.Type: GrantFiled: November 27, 1985Date of Patent: September 13, 1988Assignee: Kibun Co., Ltd.Inventors: Sachio Wakayama, Fumiyasu Ishikawa, Kunio Oishi