Patents by Inventor Fusaaki Shimizu

Fusaaki Shimizu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Amino acid derivatives having anti-tumor activity and compositions containing them
    Patent number: 4904680
    Abstract: Amino acid amides of formula (I): ##STR1## wherein R.sup.1 -R.sup.5 and Y represent a variety of organic groups and atoms (including where R.sup.2, Y and the adjacent nitrogen atom together represent a thiazolidine or pyrrolidine group) and X represents carbonyl or sulfonyl are mostly new compounds and have valuable anti-tumor and immuno-regulatory activities. They may be formulated in compositions for pharmaceutical use.
    Type: Grant
    Filed: January 22, 1988
    Date of Patent: February 27, 1990
    Assignee: Sankyo Company, Limited
    Inventors: Takashi Matsui, Mitsuo Nagano, Koichi Kitamura, Fusaaki Shimizu
  • Certain tetrahydro-furan or pyran phosphate-ethylene or propylene ammonium derivatives
    Patent number: 4794183
    Abstract: Compounds of formula (I): ##STR1## [wherein: m is 1-3; A and B are oxygen or sulfur; and one of R.sup.1 and R.sup.2 is C.sub.10 -C.sub.22 alkyl and the other is a group of formula (II). ##STR2## where: n is 2 or 3; and --NR.sup.3 R.sup.4 R.sup.5 is an amino group] and salts thereof are effective anti-cancer agents.
    Type: Grant
    Filed: January 14, 1986
    Date of Patent: December 27, 1988
    Assignee: Sankyo Company Limited
    Inventors: Norio Nakamura, Hideki Miyazaki, Fusaaki Shimizu, Kazuhiko Sasagawa
  • Rhizoxin esters and salts, their pharmaceutical use as anti-tumor agents
    Patent number: 4791128
    Abstract: Acylated derivatives of rhizoxin and of rhizoxin-2-ene may be prepared by reacting rhizoxin or rhizoxin-2-ene with an acid or reactive derivative thereof. They have excellent anti-tumor activity.
    Type: Grant
    Filed: January 11, 1988
    Date of Patent: December 13, 1988
    Assignee: Sankyo Company Limited
    Inventors: Shigenobu Okuda, Shigeo Iwasaki, Michio Namikoshi, Masao Arakawa, Fusaaki Shimizu