Abstract: The present invention provides an oral transmucosal film for delivering tadalafil through the buccal mucosa or sublingual mucosa. The film is a single layer structure containing amorphous tadalafil, one or more solubilizers, one or more penetration enhancers, and one or more adhesives to deliver the drug through a transmucosal route. Comparing with an oral tadalafil tablet, the present oral transmucosal film provides improved absorption rate and Tmax. The oral transmucosal film comprises 5%-60% by weight of amorphous tadalafil, 25-96% by weight of a film-forming material, 1-20% by weight of a solubilizer, 0.5-10% by weight of a penetration enhancer, and 1-15% by weight of an adhesive.

Abstract: The present invention provides an optimization control method for an aero-engine transient state based on reinforcement learning, and belongs to the technical field of aero-engine transient states. The method comprises: adjusting an existing twin-spool turbo-fan engine model as a model for invoking a reinforcement learning algorithm; to simultaneously satisfy high level state space and continuous action output of a real-time model, designing an Actor-Critic network model; designing a deep deterministic policy gradient (DDPG) algorithm based on an Actor-Critic frame, to simultaneously solve the problems of high-dimensional state space and continuous action output; training the model after combining the Actor-Critic frame with the DDPG algorithm; and obtaining the control law of engine acceleration transition from the above training process, and using the method to control an engine acceleration process.

Abstract: The present application relates to tunnel monitoring and measuring, more particularly, to a quick fixing device for measuring a tunnel peripheral convergence and an application method thereof. A right-angle steel sheet includes a first steel sheet and a second steel sheet which are vertically fixed with each other. The fastener vertically penetrates the first steel sheet, and an explosive powder loading portion on a rear end of the fastener is arranged at a side of the second steel sheet. The reinforcing steel sheet is respectively connected to the first steel sheet and the second steel sheet as a reinforcing bar. A through hole is provided on the reinforcing spacer, through which the reinforcing spacer is sleeved on the fastener. The reinforcing spacer is arranged between the explosive powder loading portion on the rear end of the fastener and the first steel sheet.

Abstract: Provided is a rescue capsule for shelter in tunnel construction, relating to lifesaving equipment. The rescue capsule includes a housing. A cavity of the housing includes an equipment compartment which is located at an upper portion of the cavity and a passenger compartment which is located at a lower portion of the cavity. An exterior of the housing is provided with an external skeleton. The exterior of the housing is further provided with an external indicating sign and an external rescue indicator. The housing is further provided with an explosion-proof sealing door. An oxygen cylinder, a power supply, a maintenance box, a first air purifier and a medical box are provided in the equipment compartment. Areas where the maintenance box and the medical box of the equipment compartment are provided communicate with the passenger compartment.

Abstract: The present application relates to tunnel monitoring and measuring, more particularly, to a quick fixing device for measuring a tunnel peripheral convergence and an application method thereof. A right-angle steel sheet includes a first steel sheet and a second steel sheet which are vertically fixed with each other. The fastener vertically penetrates the first steel sheet, and an explosive powder loading portion on a rear end of the fastener is arranged at a side of the second steel sheet. The reinforcing steel sheet is respectively connected to the first steel sheet and the second steel sheet as a reinforcing bar. A through hole is provided on the reinforcing spacer, through which the reinforcing spacer is sleeved on the fastener. The reinforcing spacer is arranged between the explosive powder loading portion on the rear end of the fastener and the first steel sheet.

Abstract: Provided is a rescue capsule for shelter in tunnel construction, relating to lifesaving equipment. The rescue capsule includes a housing. A cavity of the housing includes an equipment compartment which is located at an upper portion of the cavity and a passenger compartment which is located at a lower portion of the cavity. An exterior of the housing is provided with an external skeleton. The exterior of the housing is further provided with an external indicating sign and an external rescue indicator. The housing is further provided with an explosion-proof sealing door. An oxygen cylinder, a power supply, a maintenance box, a first air purifier and a medical box are provided in the equipment compartment. Areas where the maintenance box and the medical box of the equipment compartment are provided communicate with the passenger compartment.