Abstract: The present invention provides an oral transmucosal film for delivering tadalafil through the buccal mucosa or sublingual mucosa. The film is a single layer structure containing amorphous tadalafil, one or more solubilizers, one or more penetration enhancers, and one or more adhesives to deliver the drug through a transmucosal route. Comparing with an oral tadalafil tablet, the present oral transmucosal film provides improved absorption rate and Tmax. The oral transmucosal film comprises 5%-60% by weight of amorphous tadalafil, 25-96% by weight of a film-forming material, 1-20% by weight of a solubilizer, 0.5-10% by weight of a penetration enhancer, and 1-15% by weight of an adhesive.

Abstract: The present invention is directed to an aripiprazole oral soluble film and a preparation method thereof. The aripiprazole oral soluble film comprises 10-60% w/w of aripiprazole in a crystalline state and 30-95% w/w of one or more film-forming materials, wherein 90% of the aripiprazole particles have a size of ?14.3 ?m and are uniformly blended in the film without visible undispersed particles. The aripiprazole oral soluble film has excellent bioavailability, uniformity, stability, and palatability. The oral soluble film preparation is prepared by first grinding aripiprazole particles to have desired small particle sizes, then blending the aripiprazole particles with film forming materials in an aqueous solution to a uniform suspension, defoaming the suspension, and coating the suspension on a substrate and drying it to form a film.

Abstract: The present invention is directed to an aripiprazole oral soluble film and a preparation method thereof. The aripiprazole oral soluble film comprises 10-60% w/w of aripiprazole in a crystalline state and 30-95% w/w of one or more film-forming materials, wherein 90% of the aripiprazole particles have a size of ?14.3 ?m and are uniformly blended in the film without visible undispersed particles. The aripiprazole oral soluble film has excellent bioavailability, uniformity, stability, and palatability. The oral soluble film preparation is prepared by first grinding aripiprazole particles to have desired small particle sizes, then blending the aripiprazole particles with film forming materials in an aqueous solution to a uniform suspension, defoaming the suspension, and coating the suspension on a substrate and drying it to form a film.

Abstract: The present invention is directed to an aripiprazole oral soluble film and a preparation method thereof. The aripiprazole oral soluble film comprises 10-60% w/w of aripiprazole in a crystalline state and 30-95% w/w of one or more film-forming materials, wherein 90% of the aripiprazole particles have a size of ?14.3 ?m and are uniformly blended in the film without visible undispersed particles. The aripiprazole oral soluble film has excellent bioavailability, uniformity, stability, and palatability. The oral soluble film preparation is prepared by first grinding aripiprazole particles to have desired small particle sizes, then blending the aripiprazole particles with film forming materials in an aqueous solution to a uniform suspension, defoaming the suspension, and coating the suspension on a substrate and drying it to form a film.

Abstract: The present invention is directed to an aripiprazole oral soluble film and a preparation method thereof. The aripiprazole oral soluble film comprises 10-60% w/w of aripiprazole in a crystalline state and 30-95% w/w of one or more film-forming materials, wherein 90% of the aripiprazole particles have a size of ?14.3 ?m and are uniformly blended in the film without visible undispersed particles. The aripiprazole oral soluble film has excellent bioavailability, uniformity, stability, and palatability. The oral soluble film preparation is prepared by first grinding aripiprazole particles to have desired small particle sizes, then blending the aripiprazole particles with film forming materials in an aqueous solution to a uniform suspension, defoaming the suspension, and coating the suspension on a substrate and drying it to form a film.

Abstract: A buck inverter uses an input current signal compares an output current signal generated from a resistor and generates a control signal to control buck circuit switch and forces the output current follow a waveform of the input current signal. The input current signal can be generated by AC power system through a certain circuit or by a microcontroller or a waveform generator circuit. It is simple, highly efficient and low cost, because it does not use IGBT components and only uses mosfets and low inductance value of inductors.

Abstract: A single-stage power factor correction power supply has two transformers: a main transformer and an auxiliary transformer (fly-back transformer). The main transformer transfers energy from the primary circuit to the secondary circuit. The auxiliary transformer is used to correct input current waveform. A fill-valley circuit is used to stored energy when the input voltage is higher than the voltage across bulk capacitors in the fill-valley circuit and to release energy when the input voltage is lower than the voltage across the bulk capacitors in fill-valley circuit. A small capacitance value capacitor is used to improve input current waveform.

Abstract: A single-stage power factor correction power supply has two transformers: a main transformer and an auxiliary transformer (fly-back transformer). The main transformer transfers energy from the primary circuit to the secondary circuit. The auxiliary transformer is used to correct input current waveform. A fill-valley circuit is used to stored energy when the input voltage is higher than the voltage across bulk capacitors in the fill-valley circuit and to release energy when the input voltage is lower than the voltage across the bulk capacitors in fill-valley circuit. A small capacitance value capacitor is used to improve input current waveform.

Abstract: A power factor correction system is comprised of a inductor and a forward transformer. The inductor is connected to the first winding of the forward transformer. In series. The inductor is used to boost the input voltage to the design level and correct input current waveform. The forward transformer is used to prevent the large reversed current through rectifier diode and the switch. The second winding of the forward transformer is used to receive the energy through the first winding of the forward transformer to correct input current waveformer and the third winding is used to reduce the switch voltage stress.

Abstract: A single switch PFC power supply (including forward and fly-back power supply) in single stage has two transformers: one forward transformer, one main transformer. The main transformer transfers electrical power from the primary circuit to secondary circuit. The forward transformer is used to correct input current waveform. The two transformer's primary windings are connected in series. An extra winding of the forward transformer, a capacitor and two diodes are formed a no loss snubber circuit to enhance the efficiency of the power supply.

Abstract: A single stage PFC LLC power converter is consist of two transformer, one forward transformer, one main transformer. The first winding of the forward transformer is connected with a capacitor in series then paralleled with another capacitor and this circuit is connected with the primary winding of the main transformer in series as primary load circuit in LLC power converter, the energy through the main transformer is transferred to the secondary circuit and the energy through the first winding of the forward transformer is transferred to the second winding of the forward transformer to correct the input current waveform.

Abstract: A half-bridge single stage PFC power converter includes a forward transformer and a main transformer. The primary windings of two transformer are connected in series. The main transformer transmits energy from a primary circuit to a secondary circuit. The forward transformer transits energy to PFC windings of the forward transformer to correct an input current waveform. A capacitor is connected to the primary winding of the forward transformer to reduce the switching loss of the converter.

Abstract: A single stage power factor correction power supply has two transformers: a main transformer and an auxiliary transformer (forward transformer). The main transformer transfers energy form the primary circuit to the secondary circuit. The auxiliary transformer is used to correct input current waveform. The advantage of this design over the two stage power supply is that the voltage across the storage capacitor can be designed to be only slightly higher than the peak value of the rectified input voltage. Therefore, it uses less energy to correct input current waveform and results in less of an Electromagnetic Compatibility problem because it has lower input current amplitude through the inductor than that of the two stage PFC power supply.

Abstract: A single-stage power factor correction power supply has two transformers: a main transformer and an auxiliary transformer (forward transformer). The main transformer transfers energy form the primary circuit to the secondary circuit. The auxiliary transformer is used to correct input current waveform. An extra winding of the auxiliary transformer is used to reduce the voltage stress of the switch component. The advantage of this design over the two-stage power supply is that the voltage across the storage capacitor can be designed to be only slightly higher than the peak value of the rectified input voltage. Therefore, it uses less energy to correct input current waveform and results in less of an Electromagnetic Compatibility (EMC) problem because it has a lower input current amplitude through the inductor than that of the two-stage PFC power supply. It increases power supply unit reliabilty and efficiency.

Abstract: A single stage PFC LLC power converter is consist of two transformer, one forward transformer, one main transformer. The first winding of the forward transformer is connected with a capacitor in series then paralleled with another capacitor and this circuit is connected with the primary winding of the main transformer in series as primary load circuit in LLC power converter, the energy through the main transformer is transferred to the secondary circuit and the energy through the first winding of the forward transformer is transferred to the second winding of the forward transformer to correct the input current waveform.

Abstract: A single stage power factor correction power supply consists of two transformers: a main transformer and an auxiliary transformer (forward transformer). The main transformer transfers energy from the primary circuit to secondary circuit. The auxiliary transformer is used to correct input current waveform. The advantage of this design over the two stages power supply is that the voltage across storage capacitor can be designed to be only slightly higher than the peak value of the rectified input voltage. Therefore, it uses less energy to correct input current waveform and less EMC problem because it has less current through the inductor than two stage PFC power supply.

Abstract: A single switch PFC power supply (including forward and fly-back power supply) in single stage has two transformers: one forward transformer, one main transformer. The main transformer transfers electrical power from the primary circuit to secondary circuit. The forward transformer is used to correct input current waveform. The two transformer's primary windings are connected in series. An extra winding of the forward transformer, a capacitor and two diodes are formed a no loss snubber circuit to enhance the efficiency of the power supply.

Abstract: Provided herein is a power factor correction (PFC) power supply, comprising: a bridge rectifier having an input and an output, a filter capacitor connected to the output of the bridge rectifier, a transformer having a primary winding, a fly-back winding and a secondary winding, a forward diode, a fly-back diode, a storage capacitor circuit having a valley-fill circuit and a capacitor connected in parallel, and a switch connected between the primary winding and the output of the bridge rectifier. The PFC power supply features improved efficiency and low switching loss.

Abstract: Provided herein is a power factor correction (PFC) power supply, comprising: a bridge rectifier having an input and an output, a filter capacitor connected to the output of the bridge rectifier, a transformer having a primary winding, a fly-back winding and a secondary winding, a forward diode, a fly-back diode, a storage capacitor circuit having a valley-fill circuit and a capacitor connected in parallel, and a switch connected between the primary winding and the output of the bridge rectifier. The PFC power supply features improved efficiency and low switching loss.