Abstract: A smear preparation machine includes: a slide loading mechanism (2) configured to load a slide; a sample applying mechanism (3) configured to apply a blood sample to the slide; a smearing mechanism (4) configured to smear the blood sample on the slide to prepare a smear; a dripping and staining mechanism (5) configured to drip a staining reagent and a buffer solution to the smear; an air blowing mechanism configured to blow air to the staining reagent and the buffer solution on the smear for blowing mixing, such that the staining reagent and the buffer solution are mixed and cover the smear, thereby staining the smear once.