Patents by Inventor Fuyoko Sasao

Fuyoko Sasao has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Anti-human influenza virus antibody
    Patent number: 6720409
    Abstract: [Object] To provide an anti-human influenza virus antibody and an immunogenic artificial polypeptide. [Constitution] An anti-human influenza virus antibody which recognizes the stem regions of haemagglutinin molecules of the H1N1 and H2N2 subtypes and has a neutralization activity but does not recognize the stem region of the H3N2 subtype and has no neutralization activity. An immunogenic artificial polypeptide having an antigenicity substantially same as the stem regions of haemagglutinin molecules. An immunogenic artificial polypeptide having an antigenicity substantially same as the stem regions of haemagglutinin molecule and lacking the globular head region of haemagglutinin molecules. [Effect] This antibody is useful in the diagnosis and treatment of influenza A virus, while these polypeptides are useful as a vaccine.
    Type: Grant
    Filed: August 1, 2001
    Date of Patent: April 13, 2004
    Assignee: Takara Shuzo Co., Ltd.
    Inventors: Yoshinobu Okuno, Yuji Isegawa, Fuyoko Sasao, Shigeharu Ueda
  • Anti-human influenza virus antibody
    Publication number: 20020054882
    Abstract: [Object] To provide an anti-human influenza virus antibody and an immunogenic artificial polypeptide.
    Type: Application
    Filed: August 1, 2001
    Publication date: May 9, 2002
    Inventors: Yoshinobu Okuno, Yuji Isegawa, Fuyoko Sasao, Shigeharu Ueda
  • Polypeptides for use in generating anti-human influenza virus antibodies
    Patent number: 6337070
    Abstract: The invention provides an anti-human influenza virus antibody which recognizes the stem regions of haemagglutinin molecules of the H1N1 and H2N2 subtypes and has a neutralization activity but does not recognize the stem region of the H3N2 subtype and has no neutralization activity. Also provided is an immunogenic artificial polypeptide having an antigenicity substantially same as the stem region of haemagglutinin molecules, particularly lacking the globular head region of haemagglutinin molecules. This antibody is useful in the diagnosis and treatment of influenza A virus, while the polypeptides are useful as a vaccine.
    Type: Grant
    Filed: January 8, 1998
    Date of Patent: January 8, 2002
    Assignee: Takara Shuzo Co., Ltd.
    Inventors: Yoshinobu Okuno, Yuji Isegawa, Fuyoko Sasao, Shigeharu Ueda
  • Anti-human influenza virus antibody
    Patent number: 5631350
    Abstract: An anti-human influenza virus antibody is provided having the following characteristics: (a) specifically binds to the stem region of hemagglutinin of human influenza A virus subtype H3N2; (b) does not specifically bind to the stem region of hemagglutinin of human influenza A virus subtypes H1N1 and H2N2; and (c) does not specifically bind to the stem region of hemagglutinin of human influenza B virus. A composition comprising the antibody is also provided.
    Type: Grant
    Filed: April 5, 1996
    Date of Patent: May 20, 1997
    Assignee: Takara Shuzo Co., Ltd.
    Inventors: Yoshinobu Okuno, Yuji Isegawa, Fuyoko Sasao, Shigeharu Ueda
  • Anti-human influenza virus antibody
    Patent number: 5589174
    Abstract: An anti-human influenza virus antibody is provided which recognizes the stem regions of haemagglutinin molecules of the H1N1 and H2N2 subtypes and has a neutralization activity, but does not recognize the stem region of the H3N2 subtype and has no neutralization activity. Also provided is an immunogenic artificial polypeptide having an antigenicity substantially the same as the stem regions of haemagglutinin molecules. Provided further is an immunogenic artificial polypeptide having an antigenicity substantially the same as the stem regions of haemagglutinin molecule and lacking the globular head region of haemagglutinin molecules. The antibody is useful in the diagnosis and treatment of influenza A virus, while the polypeptides are useful as a vaccine.
    Type: Grant
    Filed: April 19, 1994
    Date of Patent: December 31, 1996
    Assignee: Takara Shuzo Co., Ltd.
    Inventors: Yoshinobu Okuno, Yuji Isegawa, Fuyoko Sasao, Shigeharu Ueda