Abstract: The subject relates to an isolated antibody that specifically binds to O25b antigen of multi drug resistant (MDR) E. coli strains, its medical and diagnostic use, method of producing the antibody, including an isolated nucleotide sequence, plasmids and host cells as used in the production of the antibody; and further an isolated epitope recognized the specific antibody.

Abstract: A live attenuated Shigella vaccine, which is based on a rough Shigella strain lacking LPS O-antigen which is non-invasive through a mutation of the invasion plasmid, specifically for use in the immunoprophylaxis of a subject to prevent infectious diseases, preferably enteral disease, and a Shigella strain, which is a S. flexneri 2a strain with a deletion of the rfb F, ipa B and/or ipa C genes, as well as a recombinant plasmid vector based on a mutated Shigella invasion plasmid comprising a nucleotide sequence encoding at least one heterologous antigen, wherein the plasmid is mutated in at least one of the ipa B and/or ipa C genes.

Abstract: The invention refers to an isolated antibody that specifically binds to O25b antigen of E. coli strains comprising at least an antibody heavy chain variable region (VH), which comprises any of the CDR1 to CDR3 sequences as listed in FIG. 1, and optionally further comprising an antibody light chain variable region (VL), which comprises any of the CDR4 to CDR6 sequences as listed in FIG. 1, or functionally active CDR variants of any of the forgoing CDR 1-6 sequences.

Abstract: The subject relates to an isolated antibody that specifically binds to O25b antigen of multi drug resistant (MDR) E. coli strains, its medical and diagnostic use, method of producing the antibody, including an isolated nucleotide sequence, plasmids and host cells as used in the production of the antibody; and further an isolated epitope recognized the specific antibody.

Abstract: A motion transfer apparatus comprising a frame; at least one wheel shaft operably coupled to at least one wheel, the at least one wheel shaft rotatable on the frame; a gear assembly coupled to the at least one wheel shaft; at least one pedal engaging the gear assembly and movable by an appendage within a predetermined angular range to apply a force; at least one crank arm with a predetermined length coupled to the at least one pedal and to the gear assembly for applying the force directly from the pedal to the gear assembly to rotate the at least one wheel; and a restorative member generating a restorative force to return the pedal and the at least one crank arm from a lower stroke position to an upper stroke position.

Abstract: Methods and systems providing for the generation, sending, updating, and monitoring of electronic documents (eDocuments) based on source documents created in Enterprise Resource Planning (ERP) software. An eDocument is generated based on existing source documents, external data, or from other eDocuments. The method and systems ensure that the generated eDocument is compliant with any technical requirements. The eDocument is generated using a document process which transforms a non-compliant source document into a compliant eDocument. An eDocument Framework system can include a mapping application, application interface framework (AIF), an eDocument interface, and a process manager. The AIF is configured to interact with a cloud services provider to create a highly automated process of generating, sending, updating, and monitoring the eDocuments. The cloud service provider is also configured to interact with local authorities.

Abstract: Methods, systems, and devices for rendering computer graphics using texture maps are disclosed. Multiple texture maps with disparate data types, such as a mix of integer data types for RGB colors and floating point data types for XYZ normal vector components, are passed as one texture map set to a graphics processing unit (GPU). Filter parameters and other interpolation parameters are re-used between the disparate texture maps. A user can specify a number of integer and floating point-based channels for processing at one time by the GPU, thereby customizing a texture set structure.

Abstract: An architectural planning system, that includes software and the process thereof, which actively tracks the relationship of organizational groups as well as the required connections therebetween, which information can be actively taken into account during an architectural planning phase. Generally, this provides an improved software tool and process for planning the physical locations of organizational groups within the building space. Further, changes in organizational needs can be readily modified and adapted through direct and dynamic collaboration between these parties.

Abstract: The invention refers to a cross-neutralizing antibody comprising at least one polyspecific binding site that binds to alpha-toxin (Hla) and at least one of the bi-component toxins of Staphylococcus aureus, which antibody comprises at least three complementarity determining regions (CDR1 to CDR3) of the antibody heavy chain variable region (VH), wherein A) the antibody comprises a) a CDR1 comprising or consisting of the amino acid sequence YSISSGMGWG (SEQ ID 1); and b) a CDR2 comprising or consisting of the amino acid sequence SIDQRGSTYYNPSLKS (SEQ ID 2); and c) a CDR3 comprising or consisting of the amino acid sequence ARDAGHGVDMDV (SEQ ID 3); or B) the antibody comprises at least one functionally active CDR variant of a) the parent CDR1 consisting of the amino acid sequence of SEQ ID 1; or b) the parent CDR2 consisting of the amino acid sequence of SEQ ID 2; or c) the parent CDR3 consisting of the amino acid sequence of SEQ ID 3; wherein the functionally active CDR variant comprises at least one point mutati

Abstract: The subject relates to an isolated antibody that specifically binds to O25b antigen of multi drug resistant (MDR) E. coli strains, its medical and diagnostic use, method of producing the antibody, including an isolated nucleotide sequence, plasmids and host cells as used in the production of the antibody; and further an isolated epitope recognized the specific antibody.

Abstract: A live attenuated Shigella vaccine, which is based on a rough Shigella strain lacking LPS O-antigen which is non-invasive through a mutation of the invasion plasmid, specifically for use in the immunoprophylaxis of a subject to prevent infectious diseases, preferably enteral disease, and a Shigella strain, which is a S. flexneri 2a strain with a deletion of the rfb F, ipa B and/or ipa C genes, as well as a recombinant plasmid vector based on a mutated Shigella invasion plasmid comprising a nucleotide sequence encoding at least one heterologous antigen, wherein the plasmid is mutated in at least one of the ipa B and/or ipa C genes.

Abstract: The subject relates to a cross-neutralizing antibody comprising at least one polyspecific binding site that binds to alpha-toxin (Hla) and at least one of the bi-component toxins of Staphylococcus aureus, its medical and diagnostic use, method of producing the antibody, including an isolated nucleotide sequence, plasmids and host cells as used in the production of the antibody; and further an isolated conformational epitope recognized by a specific cross-neutralizing antibody.

Abstract: The present invention relates to polyisocyanate-based impregnating resin system, which is a liquid polyisocyanate mixture, containing more than 50% by weight MDI based di- and polyisocyanates, and one or more, originally powdery inorganic hydroxides. The resin system of the invention is suitable for the preparation of prepregs. The invention relates also to the prepreg that can be manufactured with the use of the resin system, and use thereof. Among the uses of the invention one important is the use of the prepreg for lining chimneys.

Abstract: A computer-based system and method are provided for assessing extrinsic and intrinsic work characteristics of people, and storing such data for evaluation of user pre-defined groups' Workstyles and using the Workstyles and additional survey data to develop design implications for the workspace in which such groups will work in an office environment. The Workstyles encompass multiple types of Workstyles which describe characteristics of where and how individual employees work, how much control they have over their work, and what kind of work they do. The design implications provide design guidance, which are expressed in relative terms and provide suggested guidance as to the development of the individual workspaces (workstations) for a group but do not dictate the specific design thereof.

Abstract: An architectural planning system, that includes software and the process thereof, which actively tracks the relationship of organizational groups as well as the required connections therebetween, which information can be actively taken into account during an architectural planning phase. Generally, this provides an improved software tool and process for planning the physical locations of organizational groups within the building space. Further, changes in organizational needs can be readily modified and adapted through direct and dynamic collaboration between these parties.

Abstract: Methods, systems, and devices for rendering computer graphics using texture maps are disclosed. Multiple texture maps with disparate data types, such as a mix of integer data types for RGB colors and floating point data types for XYZ normal vector components, are passed as one texture map set to a graphics processing unit (GPU). Filter parameters and other interpolation parameters are re-used between the disparate texture maps. A user can specify a number of integer and floating point-based channels for processing at one time by the GPU, thereby customizing a texture set structure.

Abstract: The invention relates to amine-epoxy adducts with symmetrical and asymmetrical structures based on one hand on aliphatic, cycloaliphatic, araliphatic or aromatic mono-, di- and triamines, and on the other hand on aliphatic, cycloaliphatic and aromatic, mono-, di- or polyepoxy compounds, having an average molecular mass (Mn) of more than 300, but less than 8000, preferably less than 6000, containing at least one, preferably on an average more than one alcoholic hydroxyl group per molecule which is formed in the course of the epoxy-amine reaction, which contain at least two amino groups per molecule being able to react with isocyanate groups, among those maximum one is primary amine, the adduct molecules are of polymeric character and their viscosity is ?300 mPas at 70° C. The invention also relates to the process for the preparation of these adducts, and to their use for preparing sprayable polyurea and polyurea-polyurethane coatings.

Abstract: A method for forming a low defect density heterojunction between a first and a second compound, the first and second compounds each includes a group III element combined with a group V element in the periodic table, the method includes the steps of introducing in the deposition chamber the flux of the group III element for the first compound at substantially the same time while introducing in the deposition chamber a flux of the group V element for the second compound, stopping the flux of the group III element for the first compound after a first predetermined time period, stopping the flux of the group V element for the first compound after a second predetermined time period, and introducing in the deposition chamber a flux of the group III element the group V element for the second compound.

Abstract: A transistor heterogeneously integrating a power amplifier or switch with a low-noise amplifier having a substrate wafer selected from a group consisting of Gallium Arsenide (GaAs), Indium Phosphate (InP) and Gallium Antimonide (GaSb), the substrate having a first end and a second end, a conducting layer above the first end of the substrate, an isolation implant providing lateral isolation in the conducting layer, a first active layer deposited above the conducting layer and configured for the low-noise amplifier, and a buffer layer deposited above the conducting layer and configured for the low-noise amplifier.

Abstract: A method for forming a low defect density heterojunction between a first and a second compound, the first and second compounds each includes a group III element combined with a group V element in the periodic table, the method includes the steps of introducing in the deposition chamber the flux of the group III element for the first compound at substantially the same time while introducing in the deposition chamber a flux of the group V element for the second compound, stopping the flux of the group III element for the first compound after a first predetermined time period, stopping the flux of the group V element for the first compound after a second predetermined time period, and introducing in the deposition chamber a flux of the group III element the group V element for the second compound.