Abstract: A digital train brake testing and train preparation assistant uses a system, method, and computer program for determining a component parameter of a train. The system may include sensor nodes mounted to a respective part of the train, wherein the sensor nodes form a sensor network on a rail car, wherein railcars form a wireless mesh network, and wherein each of the sensor nodes is configured to collect data of the component of the respective part of the train and to publish the collected data into the wireless mesh network. The system may further include a server system configured to receive the published data of the wireless mesh network and to determine the component parameter of the train based on the received data. Furthermore, a user device for displaying a component parameter determined by a system, method, and computer program for determining a component parameter of a train is provided.

Abstract: A sensor test system for a pressure sensor in an electronic parking brake (EPB) of a vehicle. The pressure sensor is configured to measure a pressure in a pressure chamber or in a pressure line of the EPB. The sensor test system includes a pressure setting module configured to set the pressure; and by a detection module configured to detect, based on pressure set by the pressure setting module and based on a measured pressure from the pressure sensor, a potential malfunction of the pressure sensor, and to issue a warning signal if the potential malfunction is detected.

Abstract: A system for automatically stopping an autonomous vehicle, in which the autonomous vehicle includes a primary brake and a secondary brake controlled by least one control module or different control modules. The system includes: an error detection module configured to detect an error in the control of the primary brake or the secondary brake by the one control module or the different control modules; and a supplemental control module configured, upon a detected error by the error module, to cause a stop of the autonomous vehicle using the primary brake or the secondary brake.

Abstract: A brake control system for issuing an early warning about a malfunction of a brake of a vehicle, in which the brake is configured to receive a brake signal and to perform a braking process after receiving the brake signal. The vehicle includes a sensor to generate sensor data, indicative of an actuation force of the brake. The brake control system includes a reception module to receive the brake signal and the sensor data, and by a processing module to monitor the sensor data during subsequent stages of the braking process, to detect, based on the monitored sensor data, a potential malfunction of the brake, and to issue a warning signal if the potential malfunction is detected.

Abstract: A system for automatically stopping an autonomous vehicle, in which the autonomous vehicle includes a primary brake and a secondary brake controlled by least one control module or different control modules. The system includes: an error detection module configured to detect an error in the control of the primary brake or the secondary brake by the one control module or the different control modules; and a supplemental control module configured, upon a detected error by the error module, to cause a stop of the autonomous vehicle using the primary brake or the secondary brake.

Abstract: A scanning electron microscopy system with improved image beam stability is disclosed. The system includes an electron beam source configured to generate an electron beam and a set of electron-optical elements to direct at least a portion of the electron beam onto a portion of the sample. The system includes an emittance analyzer assembly. The system includes a splitter element configured to direct at least a portion secondary electrons and/or backscattered electrons emitted by a surface of the sample to the emittance analyzer assembly. The emittance analyzer assembly is configured to image at least one of the secondary electrons and/or the backscattered electrons.

Abstract: A monitoring and diagnostics system for a rail car that includes multiple sensor units, each comprising sensor devices and a data transfer unit, wherein the set of sensor units includes at least one power harvester, which is configured to convert ambient energy into electrical energy, and one energy storage means, which can be configured to store the electrical energy generated by the power harvester, a sensor hub which includes a communication subsystem and a receiver, wherein the data transfer units are configured, so that the sensor units transfer detected/measured data to the sensor hub and the communication subsystem is configured, so that the sensor hub transfers the data to the receiver, either with cable or wirelessly.

Abstract: Solid state forms of Venetoclax, pharmaceutical compositions thereof, and uses thereof are disclosed. Also disclosed are processes for the preparation of Venetoclax.

Abstract: Processes for the preparation of Venetoclax and Venetoclax produced by the processes are disclosed.

Abstract: A scanning electron microscopy system with improved image beam stability is disclosed. The system includes an electron beam source configured to generate an electron beam and a set of electron-optical elements to direct at least a portion of the electron beam onto a portion of the sample. The system includes an emittance analyzer assembly. The system includes a splitter element configured to direct at least a portion secondary electrons and/or backscattered electrons emitted by a surface of the sample to the emittance analyzer assembly. The emittance analyzer assembly is configured to image at least one of the secondary electrons and/or the backscattered electrons.

Abstract: A scanning electron microscopy system with improved image beam stability is disclosed. The system includes an electron beam source configured to generate an electron beam and a set of electron-optical elements to direct at least a portion of the electron beam onto a portion of the sample. The system includes an emittance analyzer assembly. The system includes a splitter element configured to direct at least a portion secondary electrons and/or backscattered electrons emitted by a surface of the sample to the emittance analyzer assembly. The emittance analyzer assembly is configured to image at least one of the secondary electrons and/or the backscattered electrons.

Abstract: A tubular reactor that produces maleic anhydride from a gas mixture containing n-butane and oxygen includes a first reaction zone including an inlet for the gas mixture and a second reaction zone including an outlet for a reaction gas mixture, a plurality of tubes extending in an axial direction through the first and second reaction zones, a temperature control system, configured for controlling a reaction temperature in each of the reaction zones independently, includes a heat transfer system for each of the reaction zones configured for controlling the temperature of a liquid coolant flowing through one of the reaction zones, and a circulation pumping system configured for controlling flow conditions of the liquid coolant flowing through the reactor and one of the heat transfer systems, and a preheating arrangement configured for preheating the gas mixture such that the gas mixture enters the first reaction zone at a predefined inlet temperature.

Abstract: In accordance with an embodiment, described herein is a system and method for provisioning cloud services across heterogeneous computing environments. A plurality of provisioning instructions stored on a configuration management server can be partitioned into a plurality of ranges. A plurality of client nodes connected to the configuration management server can be configured into a plurality of groups, each group providing one or more computing environments on one or more virtual machines for hosting a cloud service. Each computing environment in a particular group can be associated with a provisioning instruction launcher that specifies a particular range of provisioning instructions. When a virtual machine in a particular group reboots, the computing environment on the virtual machine searches for the latest provisioning instruction in the range corresponding to the particular group.

Abstract: Solid state forms of Venetoclax, pharmaceutical compositions thereof, and uses thereof are disclosed. Also disclosed are processes for the preparation of Venetoclax.

Abstract: A tubular reactor that produces maleic anhydride from a gas mixture containing n-butane and oxygen includes a first reaction zone including an inlet for the gas mixture and a second reaction zone including an outlet for a reaction gas mixture, a plurality of tubes extending in an axial direction through the first and second reaction zones, a temperature control system, configured for controlling a reaction temperature in each of the reaction zones independently, includes a heat transfer system for each of the reaction zones configured for controlling the temperature of a liquid coolant flowing through one of the reaction zones, and a circulation pumping system configured for controlling flow conditions of the liquid coolant flowing through the reactor and one of the heat transfer systems, and a preheating arrangement configured for preheating the gas mixture such that the gas mixture enters the first reaction zone at a predefined inlet temperature.

Abstract: In accordance with an embodiment, described herein is a system and method for provisioning cloud services across heterogeneous computing environments. A plurality of provisioning instructions stored on a configuration management server can be partitioned into a plurality of ranges. A plurality of client nodes connected to the configuration management server can be configured into a plurality of groups, each group providing one or more computing environments on one or more virtual machines for hosting a cloud service. Each computing environment in a particular group can be associated with a provisioning instruction launcher that specifies a particular range of provisioning instructions. When a virtual machine in a particular group reboots, the computing environment on the virtual machine searches for the latest provisioning instruction in the range corresponding to the particular group.

Abstract: A scanning electron microscopy system with improved image beam stability is disclosed. The system includes an electron beam source configured to generate an electron beam and a set of electron-optical elements to direct at least a portion of the electron beam onto a portion of the sample. The system includes an emittance analyzer assembly. The system includes a splitter element configured to direct at least a portion secondary electrons and/or backscattered electrons emitted by a surface of the sample to the emittance analyzer assembly. The emittance analyzer assembly is configured to image at least one of the secondary electrons and/or the backscattered electrons.

Abstract: A method of allocating users to core network nodes of a cellular telecommunications System, where users access the core network via a radio access network and where the nodes of the core network are grouped into a plurality of local pool areas and the local pool areas are further grouped into one or more pool areas, and each local pool area corresponds to a geographic area covered by the access network. The method comprises allocating a user to a core network node of a local pool area corresponding to the geographic area within which the user is located, maintaining the core network node while the user moves within the local pool area, and, in the event that the user moves out of the local pool area but remains in the same pool area, maintaining said allocation at least temporarily.

Abstract: The invention relates to toxin peptides capable of selectively inhibiting a Kv1.3 potassium channel protein. The toxin peptides of the invention are modified anuroctonus scorpion toxin peptides.

Abstract: The invention relates to toxin peptides capable of selectively inhibiting a Kv1.3 potassium channel protein. The toxin peptides of the invention are modified anuroctonus scorpion toxin peptides.