Patents by Inventor Gerald Guillaumet

Gerald Guillaumet has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Polynitrogen compounds and uses thereof as fluorescent chromophores
    Patent number: 10954436
    Abstract: The present invention relates to the use, as a fluorescent chromophore, of a compound with formula (I) wherein: A1 is —N— or —C(Y1)—; A2 is —N— or —C(Y2)—; A3 is —N— or —C(Y3)—; A4 is —N— or —C(Y4)—; at least one of A1, A2, A3 and A4 representing —N—; X1 is —N— or —C(Y5)—; X2 is —N— or —C(Y6)—; X3 is —N— or —C(Y7)—; and Y1, Y2, Y3, Y4, Y5, Y6 and Y7 are in particular chosen independently of one another from the group made up of: H, electron-donor groups and electron-attracting groups.
    Type: Grant
    Filed: July 19, 2016
    Date of Patent: March 23, 2021
    Assignees: UNIVERSITE D'ORLEANS, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
    Inventors: Franck Suzenet, Doina Sirbu, Gérald Guillaumet, Pascal Bonnet
  • Trisubstituted pyrido[2,3-D]pyrimidines, methods for preparing same and therapeutic uses thereof
    Patent number: 10202372
    Abstract: The present invention relates to compounds of the following general formula (I): wherein: R1 is notably a group —NRaRb, Ra and Rb forming together with the nitrogen atom onto which they are bound, a heterocycle comprising from 5 to 30 atoms, R2 is notably an aryl comprising from 5 to 30 atoms, and R3 is notably an alkenyl comprising from 1 to 20 carbon atoms.
    Type: Grant
    Filed: August 16, 2013
    Date of Patent: February 12, 2019
    Assignees: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S), UNIVERSITE D'ORLEANS
    Inventors: Sylvain Routier, Hélène Benedetti, Frédéric Buron, Marie-Aude Hiebel, Thibault Saurat, Gérald Guillaumet
  • POLYNITROGEN COMPOUNDS AND USES THEREOF AS FLUORESCENT CHROMOPHORES
    Publication number: 20180194997
    Abstract: The present invention relates to the use, as a fluorescent chromophore, of a compound with formula (I) wherein: A1 is —N— or —C(Y1)—; A2 is —N— or —C(Y2)—; A3 is —N— or —C(Y3)—; A4 is —N— or —C(Y4)—; at least one of A1, A2, A3 and A4 representing —N—; X1 is —N— or —C(Y5)—; X2 is —N— or —C(Y6)—; X3 is —N— or —C(Y7)—; and Y1, Y2, Y3, Y4, Y5, Y6 and Y7 are in particular chosen independently of one another from the group made up of: H, electron-donor groups and electron-attracting groups.
    Type: Application
    Filed: July 19, 2016
    Publication date: July 12, 2018
    Inventors: Franck SUZENET, Doina SIRBU, Gérald GUILLAUMET, Pascal BONNET
  • TRISUBSTITUTED PYRIDO[2,3-D]PYRIMIDINES, METHODS FOR PREPARING SAME AND THERAPEUTIC USES THEREOF
    Publication number: 20150203489
    Abstract: The present invention relates to compounds of the following general formula (I): wherein: R1 is notably a group —NRaRb, Ra and Rb forming together with the nitrogen atom onto which they are bound, a heterocycle comprising from 5 to 30 atoms, R2 is notably an aryl comprising from 5 to 30 atoms, and R3 is notably an alkenyl comprising from 1 to 20 carbon atoms.
    Type: Application
    Filed: August 16, 2013
    Publication date: July 23, 2015
    Inventors: Sylvain Routier, Hélène Benedetti, Frédéric Buron, Marie-Aude Hiebel, Thibault Saurat, Gérald Guillaumet
  • DERIVATIVES OF PYRIDO [3,2-D] PYRIMIDINE, METHODS FOR PREPARATION THEREOF AND THERAPEUTIC USES THEREOF
    Publication number: 20130109693
    Abstract: The present invention relates to a compound of the following general formula (I): wherein: R1 is notably H, a halogen or an aryl group, R2 is notably a halogen or an aryl group, R3 is notably a halogen, or an aryl or heteroaryl group, as well as to its pharmaceutically acceptable salts, its hydrates or its polymorphic crystalline structures, its racemates, diastereoisomers or enantiomers, except the compound 1-(2,4-diaminopyrido[3,2-d]pyrimidin-7-yl)-3,6,6-trimethyl-6,7-dihydro-1H-indol-4(5H)-one.
    Type: Application
    Filed: April 28, 2011
    Publication date: May 2, 2013
    Applicants: UNIVERSITE D'ORLEANS, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S)
    Inventors: Sylvain Routier, Gérald Guillaumet, Abdellatif Tikad, Oussama Dehbi
  • DERIVATIVES OF 10-AMINO-1,2,3,4-TETRAHYDROPYRIDO[2,1-A]ISOINDOL-6(10BH)-ONES, METHOD FOR PREPARATION THEREOF AND THERAPEUTIC USES THEREOF
    Publication number: 20120095022
    Abstract: The present invention relates to compounds having the following general formula (I): wherein: A represents a SO2 or CX group, X representing O or S; R1, R2, R?, R4 represent in particular H, R represents in particular an alkyl group or an aryl group, as well as to the pharmaceutically acceptable salts thereof, the compound of formula (I) taking the form of a pure stereoisomer or an enantiomer and/or diastereoisomer mixture, including racemic mixtures.
    Type: Application
    Filed: March 11, 2010
    Publication date: April 19, 2012
    Applicants: UNIVERSITE D'ORLEANS, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S.)
    Inventors: Sylvain Cesar Leonce Routier, Gerald Guillaumet, Rajaa Boulahjar, Laurent Meijer, Matteo Chiurato
  • 2,6-QUINOLINYL AND 2,6-NAPHTHYL DERIVATIVES, PROCESSES FOR PREPARING THEM AND THEIR USES AS VLA-4 INHIBITORS
    Publication number: 20100105681
    Abstract: The present invention concerns 2,6-quinolinyl and 2,6-naphthyl derivatives, processes for preparing them, pharmaceutical compositions containing them and their use as pharmaceuticals.
    Type: Application
    Filed: October 23, 2009
    Publication date: April 29, 2010
    Inventors: Marie-Agnes Lassoie, Laurent Knerr, Thierry Demaude, Françoise De Laveleye-Defais, Thierry Kogej, Luc Quere, Sylvain Routier, Gerald Guillaumet
  • 2,6-quinolinyl and 2,6-naphthyl derivatives, processes for preparing them and their uses as VLA-4 inhibitors
    Patent number: 7638630
    Abstract: The present invention concerns 2,6-quinolinyl and 2,6-naphthyl derivatives of formula (I), processes for preparing them, pharmaceutical compositions containing them and their use as pharmaceuticals for the treatment of VLA-4 dependent inflammatory diseases such as for example asthma, allergic rhinitis, sinusitis, conjunctivitis, food allergy, psoriasis, urticaria, pruritus, eczema, rheumatoid arthritis, inflammatory bowel disease, multiple sclerosis and atherosclerosis. Formula (I): wherein X is N or CH.
    Type: Grant
    Filed: April 15, 2003
    Date of Patent: December 29, 2009
    Assignee: UCB Pharma S.A.
    Inventors: Marie-Agnès Lassoie, Laurent Knerr, Thierry Demaude, Françoise De Laveleye-Defais, Thierry Kogej, Luc Quere, Sylvain Routier, Gerald Guillaumet
  • Heterocyclic Oxime Compounds, Process for Their Preparation and Pharmaceutical Compositions Containing Them
    Publication number: 20090274674
    Abstract: Compounds of formula (I): wherein: X represents a hydrogen or halogen atom or an alkyl group, R1, R2, R3 and R4 are as defined in the description, A represents an alkylene chain as defined in the description, B represents an alkyl or alkenyl group substituted by a group D represents a pyridine nucleus.
    Type: Application
    Filed: December 19, 2006
    Publication date: November 5, 2009
    Applicant: LES LABORATOIRES SERVIER
    Inventors: Franck Suzenet, Gerald Guillaumet, Christelle Pillard, Carine Bassene, Catherine Dacquet, Alain Ktorza, Daniel-Henri Caignard
  • 2,6-Quinolinyl And 2,6-Naphthyl Derivatives, Processes For Preparing Them And Their Uses As Vla-4 Inhibitors
    Publication number: 20080064720
    Abstract: The present invention concerns 2,6-quinolinyl and 2,6-naphthyl derivatives of formula (I), processes for preparing them, pharmaceutical compositions containing them and their use as pharmaceuticals for the treatment of VLA-4 dependent inflammatory diseases such as for example asthma, allergic rhinitis, sinusitis, conjunctivitis, food allergy, psoriasis, urticaria, pruritus, eczema, rheumatoid arthritis, inflammatory bowel disease, multiple sclerosis and atherosclerosis. Formula (I): wherein X is N or CH.
    Type: Application
    Filed: April 15, 2003
    Publication date: March 13, 2008
    Applicant: UCB, S.A.
    Inventors: Marie-Agnes Lassoie, Laurent Knerr, Theirry Demaude, Francoise De Laveleye-Defais, Thierry Kogej, Luc Quere, Sylvain Routier, Gerald Guillaumet
  • Polycyclic azaindole compounds
    Patent number: 7235550
    Abstract: The invention relates to compounds of formula (I): wherein: G1 represents an alkylene chain as defined in the description, A represents R2 and R3 represent hydrogen, alkyl, alkoxy or hydroxy or together form oxo, R4 and R5 represent hydrogen, R1 is as defined in the description, and medicinal products containing the same which are useful in treating or preventing melatoninergic disorders.
    Type: Grant
    Filed: October 9, 2002
    Date of Patent: June 26, 2007
    Assignee: Les Laboratoires Servier
    Inventors: Gérald Guillaumet, Marie-Claude Viaud, Hervé Van de Poel, Philippe Delagrange, Caroline Bennejean, Pierre Renard
  • Substituted biphenyl compounds
    Publication number: 20070123529
    Abstract: The invention relates to compound of formula (I) wherein: B represents hydrogen, COOR, CONRR?, or (C1-C6)alkyl substituted by COOR, CONRR?, or OR, G1 represents —X?—(CH2)n—X—(CH2)m—X?— chain wherein X, X?, X?, n and m are as defined in the description, Cy represents a grouping of formula (II) or (III): G2 represents alkylene chain as defined in the description, and A represents NRCOR?, NRCSR?, CONRR?, CSNRR?, NRCONR?R?, or NRCSNR?R?. and medicinal products containing the same which are useful in treating or preventing melatoninergic disorders.
    Type: Application
    Filed: December 18, 2006
    Publication date: May 31, 2007
    Applicant: LES LABORATOIRES SERVIER
    Inventors: Carole Descamps-Francois, Said Yous, Daniel Lesieur, Gerald Guillaumet, Marie-Claude Viaud, Herve Da-Costa, Caroline Bennejean, Philippe Delagrange, Pierre Renard
  • Substituted cyclic compounds, preparation method and pharmaceutical compositions containing them
    Patent number: 7183318
    Abstract: The invention concerns compounds of formula (1): R-A-R? wherein: A is as defined in the description; R represent a group (V), (VI), (VII), or (VIII), where E, Q, R1, R2, R3, v and R4 are as defined in the description; R? represents a —(CH2)t—R5 group wherein t and R5 are as defined in the description, and medicaments containing the same
    Type: Grant
    Filed: June 16, 2003
    Date of Patent: February 27, 2007
    Assignee: Les Laboratoires Servier
    Inventors: Daniel Lesieur, Frederique Klupsch, Gerald Guillaumet, Marie-Claude Viaud, Michel Langlois, Caroline Bennejean, Pierre Renard, Philippe Delagrange
  • Substituted biphenyl derivatives, method for preparing same and pharmaceutical compositions containing same
    Patent number: 7161035
    Abstract: The invention relates to compounds of formula (I): wherein: B represents a hydrogen atom, a COOR group, a CONRR? group, or a (C1–C6)alkyl group substituted by a COOR, CONRR? or OR group, G1 represents a —X?—(CH2)n—X—(CH2)m—X?— chain wherein X, X?, X?, n and m are as defined in the description, Cy represents a grouping of formula (II) or (III): G2 represents an alkylene chain as defined in the description, and A represents a NRCOR?, NRCSR?, CONRR?, CSNRR?, NRCONR?R? or NRCSNR?R? group.
    Type: Grant
    Filed: July 16, 2001
    Date of Patent: January 9, 2007
    Assignee: Les Laboratoires Servier
    Inventors: Carole Descamps-Francois, Said Yous, Daniel Lesieur, Gérald Guillaumet, Marie-Claude Viaud, Hervé Da Costa, Caroline Bennejean, Philippe Delagrange, Pierre Renard
  • Substituted cyclic compounds
    Patent number: 7126012
    Abstract: The invention concerns compounds of formula (I): R-A-R? wherein: A is as defined in the description; R represents a group (V), (VI), (VII) or (VIII), where E, Q, R1, R2, R3, v and R4 are as defined in the description; R? represents a —(CH2)t-R5 group wherein t and R5 are as defined in the description
    Type: Grant
    Filed: September 23, 2004
    Date of Patent: October 24, 2006
    Assignee: Les Laboratoires Servier
    Inventors: Daniel Lesieur, Frederique Klupsch, Gerald Guillaumet, Marie-Claude Viaud, Michel Langlois, Caroline Bennejean, Pierre Renaud, Philippe Delagrange
  • Substituted cyclic compounds
    Patent number: 7115752
    Abstract: The invention concerns compounds of formula (I): R—A—R? wherein: A is as defined in the description; R represents a group (V), (VI), (VII) or (VIII), where E, Q, R1, R2, R3, v and R4 are as defined in the description; R? represents a —(CH2)t-R5 group wherein t and R5 are as defined in the description.
    Type: Grant
    Filed: September 23, 2004
    Date of Patent: October 3, 2006
    Assignee: Les Laboratoires Servier
    Inventors: Daniel Lesieur, Frederique Klupsch, Gerald Guillaumet, Marie-Claude Viaud, Michel Langlois, Caroline Bennejean, Pierre Renaud, Philippe Delagrange
  • Heterocyclic derivatives, preparation method and pharmaceutical compositions containing same
    Patent number: 6919362
    Abstract: Compounds of formula (I): wherein: X represents an oxygen or a sulphur or CH2 or R1 and R2 represent a hydrogen atom, or a group as defined in the description, A represents an alkylene chain as described in the description, B is as defined in the description, R3 and R4 represent a hydrogen atom or a group as defined in the description, D represents an optionally substituted benzene, optionally substituted pyrazine, optionally substituted pyrimidine or optionally substituted pyridazine and medicinal products containing the same which are useful in treating or preventing melatoninergic disorders.
    Type: Grant
    Filed: February 1, 2001
    Date of Patent: July 19, 2005
    Assignee: Les Laboratoires Servier
    Inventors: Daniel Lesieur, Elodie Blanc-Delmas, Said Yous, Patrick Depreux, Gérald Guillaumet, Catherine Dacquet, Nigel Levens, Jean Albert Boutin, Caroline Bennejean, Pierre Renard
  • Substituted cyclic compounds
    Publication number: 20050124682
    Abstract: The invention concerns compounds of formula (I): R-A-R? wherein: A is as defined in the description; R represents a group (V), (VI), (VII) or (VIII), where E, Q, R1, R2, R3, v and R4 are as defined in the description; R? represents a —(CH2)t-R5 group wherein t and R5 are as defined in the description.
    Type: Application
    Filed: September 23, 2004
    Publication date: June 9, 2005
    Inventors: Daniel Lesieur, Frederique Klupsch, Gerald Guillaumet, Marie-Claude Viaud, Michel Langlois, Caroline Bennejean, Pierre Renard, Philippe Delagrange
  • Substituted cyclic compounds, preparation method and pharmaceutical compositions containing them
    Patent number: 6872851
    Abstract: The invention concerns compounds of formula (I): R—A—R? wherein: A is as defined in the description; R represent, a group (V), wherein R?a and R?a are as defined in the description, or R forms with A a cyclic structure as defined in the description; R? represents a (CH2)t—R2 group wherein q, t, and R2 are as defined in the description. The invention is useful for preparing medicines.
    Type: Grant
    Filed: May 10, 1999
    Date of Patent: March 29, 2005
    Assignee: Les Laboratories Servier
    Inventors: Daniel Lesieur, Frédérique Klupsch, Gérald Guillaumet, Marie-Claude Viaud, Michel Langlois, Caroline Bennejean, Pierre Renard, Philippe Delagrange
  • Substituted cyclic compounds
    Publication number: 20050059729
    Abstract: The invention concerns compounds of formula (I): R-A-R? wherein: A is as defined in the description; R represents a group (V), (VI), (VII) or (VIII), where E, Q, R1, R2, R3, v and R4 are as defined in the description; R? represents a —(CH2)t-R5 group wherein t and R5 are as defined in the description.
    Type: Application
    Filed: September 23, 2004
    Publication date: March 17, 2005
    Inventors: Daniel Lesieur, Frederique Klupsch, Gerald Guillaumet, Marie-Claude Viaud, Michel Langlois, Caroline Bennejean, Pierre Renard, Philippe Delagrange