Patents by Inventor Gökcen Eraslan

Gökcen Eraslan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHOD FOR EXTRACTING NUCLEI OR WHOLE CELLS FROM FORMALIN-FIXED PARAFFIN-EMBEDDED TISSUES
    Publication number: 20220411783
    Abstract: The subject matter disclosed herein is generally directed to isolating single cells and nuclei from tissue samples for use in the analysis of single cells from archived biological samples. The subject matter disclosed herein is directed to isolating single cells and nuclei from formalin-fixed paraffin-embedded (FFPE) tissues. The subject matter disclosed herein is also directed to isolating single nuclei that preserve ribosomes or ribosomes and rough ER from frozen tissues. The subject matter disclosed herein is also directed to therapeutic targets, diagnostic targets and methods of screening for modulating agents.
    Type: Application
    Filed: October 11, 2019
    Publication date: December 29, 2022
    Inventors: Aviv Regev, Cristin McCabe, Eugene Drokhlyansky, Alexandre Melnikov, Orit Rozenblatt-Rosen, Christopher S. Smillie, Ramnik J. Xavier, Orr Ashenberg, Gökcen Eraslan, Hattie Chung
  • COMPOSITIONS AND METHODS FOR TARGETING MULTINUCLEATED CELLS
    Publication number: 20220249701
    Abstract: The present invention provides for methods and compositions for specifically targeting a nuclei type in a multinucleated cell or population of multinucleated cells, wherein the composition comprises one or more nucleotide sequences operably linked to one or more regulatory sequences specifically active in the nuclei.
    Type: Application
    Filed: May 14, 2020
    Publication date: August 11, 2022
    Inventors: Aviv Regev, Eugene Drokhlyansky, Orit Rozenblatt-Rosen, Gökcen Eraslan