Patents by Inventor G Nelson
G Nelson has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 12279988Abstract: A shouldered arm sling provided for treatment of various injuries to the arm, wrist, hand, of a patient, during convalescence, the sling includes primary straps and a saddle-style member, connecting with the front and back straps of the sling, the saddle-style member having a pair of straps, one strap rests upon the upper shoulder of the patient, the second strap rests upon the lateral side of the patient's shoulder, and the bifurcated straps have a flexible fabric type member connecting intermediately thereof, in order to provide for the dissemination of the generated forces on the shoulder from the weight of the arm being supported during its healing. The flexible fabric forms the saddle strap into a concaved configuration, to ergonomically fit upon the upper segment of the supporting shoulder, to add stability and comfort to the patient.Type: GrantFiled: January 29, 2022Date of Patent: April 22, 2025Inventors: Preston G. Nelson, George A Paletta
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Publication number: 20250040890Abstract: An example system includes an implantable medical device (IMD), processing circuitry, and communication circuitry. The IMD is configured to receive signals from sensors, determine a plurality of detected patient metrics based on the received signals, and store the plurality of determined patient metrics in the memory. The processing circuitry is to generate higher resolution diagnostic information based on the plurality of patient metrics during an initiated period of time, wherein the initiated period of time is initiated based on an intervention being provided to the patient and/or receiving a user input. The higher resolution diagnostic information is of at least one of the plurality of patient metrics and indicative of heart recovery. The communication circuitry is configured to transmit the higher resolution diagnostic information to indicate a degree of recovery for patient metrics indicative of heart recovery.Type: ApplicationFiled: October 22, 2024Publication date: February 6, 2025Inventors: Juliana E. Pronovici, Shantanu Sarkar, Amanda D. Taylor, Kate Arnebeck, Ekaterina B. Morgounova, Veronica Ramos, Sean R. Landman, Hyun J. Yoon, Steven G. Nelson, Jodi L. Redemske
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Publication number: 20250037461Abstract: Embodiments are disclosed for a method including obtaining a region of interest of a current frame of a video sequence depicting an object. The method may further include determining, by a mask propagation model, a likelihood of each pixel of the current frame being associated with the object in the region of interest of the current frame based on the region of interest of the current frame and a fixed number of previous frames of the video sequence including the object. The method may further include replacing a previous frame of the fixed number of previous frames with the current frame. The method may further include displaying the current frame of the video sequence including a masked object in the region of interest of the current frame based on the likelihood of one or more pixels of the current frame being associated with the object.Type: ApplicationFiled: July 28, 2023Publication date: January 30, 2025Applicant: Adobe Inc.Inventors: Joon-Young LEE, Seoung Wug OH, John G. NELSON, Wujun WANG
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Patent number: 12206930Abstract: Embodiments of the present disclosure provide, a method, a system, and a computer storage media that provide mechanisms for multimedia effect addition and editing support for text-based video editing tools. The method includes generating a user interface (UI) displaying a transcript of an audio track of a video and receiving, via the UI, input identifying selection of a text segment from the transcript. The method also includes in response to receiving, via the UI, input identifying selection of a particular type of text stylization or layout for application to the text segment. The method further includes identifying a video effect corresponding to the particular type of text stylization or layout, applying the video effect to a video segment corresponding to the text segment, and applying the particular type of text stylization or layout to the text segment to visually represent the video effect in the transcript.Type: GrantFiled: January 13, 2023Date of Patent: January 21, 2025Assignee: Adobe Inc.Inventors: Kim Pascal Pimmel, Stephen Joseph Diverdi, Jiaju MA, Rubaiat Habib, Li-Yi Wei, Hijung Shin, Deepali Aneja, John G. Nelson, Wilmot Li, Dingzeyu Li, Lubomira Assenova Dontcheva, Joel Richard Brandt
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Patent number: 12106398Abstract: Embodiments are disclosed for a machine learning-based chroma keying process. The method may include receiving an input including an image depicting a chroma key scene and a color value corresponding to a background color of the image. The method may further include generating a preprocessed image by concatenating the image and the color value. The method may further include providing the preprocessed image to a trained neural network. The method may further include generating, using the trained neural network, an alpha matte representation of the image based on the preprocessed image.Type: GrantFiled: April 21, 2022Date of Patent: October 1, 2024Assignee: Adobe Inc.Inventors: Seoung Wug Oh, Joon-Young Lee, Brian Price, John G. Nelson, Wujun Wang, Adam Pikielny
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Patent number: 12060615Abstract: The present invention provides methods for discovering agents that are effective in reversing epigenetic silencing by inhibiting the interaction of methyl-binding (MBD) proteins with methylated genomic DNA. Also provided are methods for reactivating silenced genes having CpG island hypermethylation along with methods for treatment and prevention of diseases, such as cancer and sickle cell anemia, by administering an agent that modulates methyl-binding domain (MBD) protein-mediated transcriptional repression, thereby increasing gene transcription to prevent or treat disease. Additionally, compounds identified by the present invention useful for treatment and prevention of diseases, such as cancer and sickle cell anemia, are provided.Type: GrantFiled: February 25, 2019Date of Patent: August 13, 2024Assignee: The Johns Hopkins UniversityInventors: William G. Nelson, Srinivasan Yegnasubramanian, Xiaohui Lin, Traci J. Speed, Zachery Reichert
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Publication number: 20240244287Abstract: Embodiments of the present disclosure provide, a method, a system, and a computer storage media that provide mechanisms for multimedia effect addition and editing support for text-based video editing tools. The method includes generating a user interface (UI) displaying a transcript of an audio track of a video and receiving, via the UI, input identifying selection of a text segment from the transcript. The method also includes in response to receiving, via the UI, input identifying selection of a particular type of text stylization or layout for application to the text segment. The method further includes identifying a video effect corresponding to the particular type of text stylization or layout, applying the video effect to a video segment corresponding to the text segment, and applying the particular type of text stylization or layout to the text segment to visually represent the video effect in the transcript.Type: ApplicationFiled: January 13, 2023Publication date: July 18, 2024Inventors: Kim Pascal PIMMEL, Stephen Joseph DIVERDI, Jiaju MA, Rubaiat HABIB, Li-Yi WEI, Hijung SHIN, Deepali ANEJA, John G. NELSON, Wilmot LI, Dingzeyu LI, Lubomira Assenova DONTCHEVA, Joel Richard BRANDT
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Publication number: 20230405690Abstract: Various examples embodiments are directed to issues such as those addressed above and/or others which may become apparent from the following disclosure concerning the involving the attachment of a fixture to a vertical surface.Type: ApplicationFiled: June 15, 2023Publication date: December 21, 2023Inventor: William G. Nelson
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Publication number: 20230342991Abstract: Embodiments are disclosed for a machine learning-based chroma keying process. The method may include receiving an input including an image depicting a chroma key scene and a color value corresponding to a background color of the image. The method may further include generating a preprocessed image by concatenating the image and the color value. The method may further include providing the preprocessed image to a trained neural network. The method may further include generating, using the trained neural network, an alpha matte representation of the image based on the preprocessed image.Type: ApplicationFiled: April 21, 2022Publication date: October 26, 2023Applicant: Adobe Inc.Inventors: Seoung Wug OH, Joon-Young LEE, Brian PRICE, John G. NELSON, Wujun WANG, Adam PIKIELNY
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Publication number: 20230100402Abstract: The disclosure generally relates to compositions and methods for the treatment of cancer. In some aspects, disclosed herein are methods for the induction of synthetic lethality with epigenetic therapy (ISLET) using a combination of at least one epigenetic compound and at least one chemotherapeutic agent. Also disclosed herein are screening methods for identifying compounds that induce killing of cancer cells when combined with at least one epigenetic compound. Further disclosed herein are methods of potentiating a therapeutic effect of a chemotherapeutic agent against a cancer, comprising administering to a subject having the cancer an epigenetic compound in an amount effective to potentiate the therapeutic effect of the chemotherapeutic agent against the cancer.Type: ApplicationFiled: September 16, 2022Publication date: March 30, 2023Inventors: Srinivasan Yegnasubramanian, William G. Nelson, Ajay Vaghasia, Philipp Nuhn
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Publication number: 20230003718Abstract: Provided herein are methods for determining a rate of DNA double strand repair on a DNA strand in a cell that include (a) delivering a reporter gene, a gene-editing agent, and a gene-repair template into a cell, wherein the gene-editing agent generates a DNA double strand break on the DNA strand; (b) detecting a change in reporter gene expression, wherein the change in reporter gene expression indicates the presence of a DNA double strand repair event; and (c) analyzing the change in reporter gene expression, thereby determining the rate of DNA double strand repair on the DNA strand in the cell.Type: ApplicationFiled: June 21, 2022Publication date: January 5, 2023Inventors: Srinivasan Yegnasubramanian, Chaya Steinberg, William G. Nelson
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Patent number: 11491174Abstract: The disclosure generally relates to compositions and methods for the treatment of cancer. In some aspects, disclosed herein are methods for the induction of synthetic lethality with epigenetic therapy (ISLET) using a combination of at least one epigenetic compound and at least one chemotherapeutic agent. Also disclosed herein are screening methods for identifying compounds that induce killing of cancer cells when combined with at least one epigenetic compound. Further disclosed herein are methods of potentiating a therapeutic effect of a chemotherapeutic agent against a cancer, comprising administering to a subject having the cancer an epigenetic compound in an amount effective to potentiate the therapeutic effect of the chemotherapeutic agent against the cancer.Type: GrantFiled: June 6, 2018Date of Patent: November 8, 2022Assignee: The Johns Hopkins UniversityInventors: Srinivasan Yegnasubramanian, William G. Nelson, Ajay Vaghasia, Philipp Nuhn
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Patent number: 11486241Abstract: The flow of well treatment fluids may be diverted from a high permeability zone to a low permeability zone within a fracture network within a subterranean formation by use of a mixture comprising a dissolvable diverter and a proppant. At least a portion of the high permeability zone is propped open with the proppant of the mixture and at least a portion of the high permeability zone is blocked with the diverter. A fluid is then pumped into the subterranean formation and into a lower permeability zone of the formation farther from the wellbore. The diverter in the high permeability zones may then be dissolved at in-situ reservoir conditions and hydrocarbons produced from the high permeability propped zones of the fracture network. The mixture has particular applicability in the enhancement of production or hydrocarbons from high permeability zones in a fracture network located near the wellbore.Type: GrantFiled: March 13, 2018Date of Patent: November 1, 2022Assignee: Baker Hughes Holdings LLCInventors: Scott G. Nelson, Harold Dean Brannon, Jimie Devon Lemons, Thomas Ray Starks, II, D. V. Satyanarayana Gupta
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Publication number: 20220241103Abstract: A shouldered arm sling provided for treatment of various injuries to the arm, wrist, hand, of a patient, during convalescence, the sling includes primary straps and a saddle-style member, connecting with the front and back straps of the sling, the saddle-style member having a pair of straps, one strap rests upon the upper shoulder of the patient, the second strap rests upon the lateral side of the patient's shoulder, and the bifurcated straps have a flexible fabric type member connecting intermediately thereof, in order to provide for the dissemination of the generated forces on the shoulder from the weight of the arm being supported during its healing. The flexible fabric forms the saddle strap into a concaved configuration, to ergonomically fit upon the upper segment of the supporting shoulder, to add stability and comfort to the patient.Type: ApplicationFiled: January 29, 2022Publication date: August 4, 2022Inventors: Preston G. Nelson, George A. Paletta
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Publication number: 20220228969Abstract: An optical device includes a low-noise illumination source, a support device, an ultra low-noise detector, an analog-to-digital converter, and a controller. The low-noise illumination source is configured to generate a single beam of radiation. The support device is configured to support an object and to pass the single beam of radiation through the object. The object directly blocks, absorbs, or deflects portions of the single beam of radiation, thereby directly modulating the single beam of radiation. The low-noise detector is configured to detect the modulated single beam of radiation and to output an analog signal representative of vibrational spectra of the object. The modulated single beam of radiation is non-interferometric. The analog-to-digital converter is configured to convert the detected analog signal into a digital signal. The controller is configured to analyze and generate vibrational spectra of the object from the digital signal represented as a range of events over time.Type: ApplicationFiled: April 1, 2022Publication date: July 21, 2022Applicant: Digital Harmonic LLCInventors: Paul Reed SMITH, William G. NELSON, Shane G.W. MORRIS, Sandor SZALAY, Jonathan B. COULTER, Frederick M. SLAY, Eric K. PRITCHARD
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Patent number: 11334003Abstract: A binary ink developer (BID) may include a power supply electrically coupled to an electrode, a developer roller, and a cleaner roller. The BID may also include a controller to determine a level of image ghosting based on a sum of currents at the electrode, the developer roller and the cleaner roller, and instruct the power supply to provide an adjusted voltage to the cleaner roller in response to a determination of the level of image ghosting.Type: GrantFiled: December 18, 2018Date of Patent: May 17, 2022Assignee: Hewlett-Packard Development Company, L.P.Inventor: Eric G. Nelson
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Publication number: 20220146950Abstract: A photoconductor marking apparatus is disclosed. The apparatus includes a radiation source to emit radiation capable of irreversibly modifying photoconductive properties of a layer of a multi-layered photoconductor. The apparatus also includes processing apparatus to: determine a pattern to be applied to a photoconductor to be used in a print apparatus, the photoconductor having an imaging area within which print agent is to be deposited; and control the radiation source to direct radiation towards the photoconductor in a region outside the imaging area, so as to irreversibly modify photoconductive properties of a layer of the photoconductor according to the determined pattern. A method and a machine-readable medium are also disclosed.Type: ApplicationFiled: October 18, 2019Publication date: May 12, 2022Applicant: Hewlett-Packard Development Company, L.P.Inventors: Eric G. NELSON, Barry J. OLDFIELD
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Patent number: 11320761Abstract: An electrophotographic printer includes a charge roller in charge-transferring relation to a photoconductive imaging portion. The printer may determine an AC voltage setpoint of the charge roller.Type: GrantFiled: December 20, 2018Date of Patent: May 3, 2022Assignee: Hewlett-Packard Development Company, L.P.Inventors: Seongsik Chang, Brad Thomas Dransfield, Eric G. Nelson, Bruce J. Jackson, Omer Gila, Anthony William McLennan, Asaf Anufa, Daniel Espinosa
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Patent number: 11293853Abstract: Disclosed are systems and methods for measuring vibrational spectra of a living cells and tissue that includes a low noise consistent optical source creating a photon beam, a support device, a photon-to-electron converter/detector outputting a streamed analog electrical signal, an analog-to-digital converter, and a digital signal processor with specialized software for measuring and characterizing the signal contained in the photon beam and its subsequent detector's streamed analog converted to digital signal. Motion of the living sample causes modulation to the photon beam as it passes through the living samples by how much of the photon beam is blocked, absorbed or deflected. In addition, specific sub-cellular vibrational features can be segregated utilizing fluorescent markers.Type: GrantFiled: September 10, 2019Date of Patent: April 5, 2022Assignee: Digital Harmonic LLCInventors: Paul Reed Smith, William G. Nelson, Shane G. W. Morris, Sandor Szalay, Jonathan B. Coulter, Frederick M. Slay, Eric K. Pritchard
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Patent number: 11213955Abstract: A system and method for operating at least one stowable automated robotic pod in a workplace having a workpiece is disclosed. The pod includes a robot on a base that can also include one or both of a tool nest and process equipment. A door to subfloor storage allows the pod to raise its base vertical, placing the robot into the desired vertical position in the workspace. Once operations on the workpiece are complete, the pod withdraws back to the subfloor storage and the doors to the storage volume close.Type: GrantFiled: January 31, 2017Date of Patent: January 4, 2022Assignee: ABB Schweiz AGInventors: Michael G. Nelson, Timothy A. Brownlee, Robert J. Santen, Didier M. Rouaud, Douglas B. Polkinghome