Patents by Inventor Günther Schumacher

Günther Schumacher has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for the production of proteins in soluble form by modulation of an inducible promoter
    Patent number: 6284484
    Abstract: The present invention provides a process for the expression in appropriate host cells of recombinant DNA which is under the control of an inducible promotor. In order to obtain the soluble form of recombinant protein, which would usually be obtained in insoluble form, the induction of the promotor is limited to less than 10% of the maximum induction in comparison with a standard system and the transcription rate of the DNA coding for the protein is correspondingly limited.
    Type: Grant
    Filed: June 27, 1991
    Date of Patent: September 4, 2001
    Assignee: Roche Diagnostics GmbH
    Inventors: Erhard Kopetzki, Günther Schumacher
  • Expression vector for the regulatable expression of foreign genes in prokaryotes
    Patent number: 6190906
    Abstract: The invention provides an expression vector useful in expressing foreign genes in procaryotes. The vector consists of the promotor/operator region and initiation point of translation of the mg1 operon. This combination is referred to as a regulation sequence. In order to prepare this, desired portions of the mg1 operon are cut from the genome of a cell which can utilize galactose via appropriate restriction endonucleases. This is then inserted into a DNA vector.
    Type: Grant
    Filed: January 23, 1989
    Date of Patent: February 20, 2001
    Assignee: Roche Diagnostics GmbH
    Inventors: Günther Schumacher, Michael Jarsch, Winfried Boos