Patents by Inventor Gérald Guillaumet

Gérald Guillaumet has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 5242923
    Abstract: The invention relates to the compounds of general formula (I): ##STR1## in which: R.sub.1, R.sub.2, R.sub.3, R.sub.4, A, Z and m are as defined in the description, their isomers, epimers and diastereoisomers,their addition salts with a pharmaceutically acceptable acid and, when R1 and R.sub.2 each represent a hydrogen atom, their addition salts with a pharmaceutically acceptable base.
    Type: Grant
    Filed: February 21, 1992
    Date of Patent: September 7, 1993
    Assignee: Adir et Compagnie
    Inventors: Gerald Guillaumet, Christine Flouzat, Michelle Devissaguet, Pierre Renard, Daniel H. Caignard, Gerard Adam
  • Patent number: 5190960
    Abstract: Compounds of general formula (I): ##STR1## in which: R.sub.1 and R.sub.2 each represent a hydrogen atom or, with the nitrogen and oxygen which bear them, form an --O--CO--N link,W represents a halogen atom or a lower alkyl or alkoxy group optionally substituted with one or more halogen atoms, such as trifluoromethyl, and m being between 0 and 3,A is a linear or branched alkyl radical comprising from 1 to 6 carbon atoms,R.sub.3 and R.sub.4 are defined in the description.
    Type: Grant
    Filed: November 12, 1991
    Date of Patent: March 2, 1993
    Assignee: Adir et Compagnie
    Inventors: Gerald Guillaumet, Christine Flouzat, Daniel H. Caignard, Pierre Renard, Michelle Devissaguet, Beatrice Guardiola
  • Patent number: 5155116
    Abstract: Compounds of general formula (I): ##STR1## in which: R.sub.1 and R.sub.2 each represent a hydrogen atom or, with the nitrogen and oxygen which bear them, form an --O--CO--N link,W represents a halogen atom or a lower alkyl or alkoxy group optionally substituted with one or more halogen atoms, such as trifluoromethyl, and m being between 0 and 3,A is a linear or branched alkyl radical comprising from 1 to 6 carbon atoms,R.sub.3 and R.sub.4 are defined in the description have medicinal properties.
    Type: Grant
    Filed: June 6, 1991
    Date of Patent: October 13, 1992
    Assignee: Adir et Compagnie
    Inventors: Gerald Guillaumet, Christine Flouzat, Daniel H. Caignard, Pierre Renard, Michelle Devissaguet, Beatrice Guardiola
  • Patent number: 5130311
    Abstract: The invention relates to the analgesic compounds of general formula (I): ##STR1## in which: R.sub.1, R.sub.2, R.sub.3, R.sub.4, A, Z and m are as defined in the description, their isomers, epimers and diastereoisomers, their addition salts with a pharmaceutically acceptable acid and, when R.sub.1 and R.sub.2 each represent a hydrogen atom, their addition salts with a pharmaceutically acceptable base.
    Type: Grant
    Filed: November 15, 1991
    Date of Patent: July 14, 1992
    Assignee: Adir et Compagnie
    Inventors: Gerald Guillaumet, Christine Flouzat, Michelle Devissaguet, Pierre Renard, Daniel H. Caignard, Gerard Adam
  • Patent number: 5084456
    Abstract: Compounds of general formula (I): ##STR1## in which: R.sub.1 and R.sub.2 each represent a hydrogen atom or, with the oxygen and nitrogen, form an --O--CO--N-- linkage,W represents a halogen atom or a lower alkyl or alkoxy group optionally substituted with one or more halogen atoms, such as trifluoromethyl, and m being between 0 and 3,A represents a linear or branched lower alkylene group, andAr represents an aryl or heteroaryl group optionally substituted with one or more halogen atoms or with one or more lower alkyl, hydroxy, hydroxysulfonyloxy, lower alkoxy or aryloxy groups optionally substituted with one or more halogen atoms, such as a trifluoromethyl group,on the understanding that lower alkyl or lower alkyloxy radical is understood to mean a linear or branched alkyl group comprising from 1 to 6 carbon atom, their isomers, epimers and diastereoisomers. Medicinal products useful in the treatment of pain.
    Type: Grant
    Filed: August 7, 1990
    Date of Patent: January 28, 1992
    Assignee: Science et Organisation
    Inventors: Gerald Guillaumet, Christine Flouzat, Jacqueline Bonnet
  • Patent number: 5077408
    Abstract: Process for the synthesis of compounds of formula (I): ##STR1## their pyridinium salts and N-oxides, in which formula: the nitrogen of the pyridine ring is situated in the .alpha.-, .beta.-, .gamma.- or .delta.-position with respect to the ring junction;R.sup.1 represents a halogen, a substituted or unsubstituted alkyl, a substituted or unsubstituted alkoxy or a nitro, substituted or unsubstituted amino, phenyl or cyano group;0.ltoreq.m.ltoreq.2;R.sup.2 represents a lower alkyl or cycloalkyl group, a 5- or 6-membered heterocycle containing 1 or 2 hetero atoms, substituted or otherwise, or an aryl group ##STR2## such that: R.sup.3 represents a halogen, a substituted or unsubstituted alkyl, a substituted or unsubstituted alkoxy or a nitro, phenyl, substituted or unsubstituted sulfonyl, cyano, thioalkyl, substituted or unsubstituted amino, substituted or unsubstituted sulfinyl, mercapto, hydroxyl or ester group,0.ltoreq.n.ltoreq.
    Type: Grant
    Filed: September 17, 1990
    Date of Patent: December 31, 1991
    Assignee: Science et Organisation
    Inventors: Gerald Guillaumet, Christine Flouzat
  • Patent number: 5061713
    Abstract: Compound of general formula (I): ##STR1## in which: X, Y, Z and T each represent, independently of one another, a nitrogen atom, a --CH.dbd. group or a group CW, in which W represents a halogen atom or a lower alkyl or alkoxy group optionally substituted with one or more halogen atoms, such as a trifluoromethyl group, on condition that only one of them represents a nitrogen atom,Ra, Rb, Rc, Rd and Re represent, independently of one another, a hydrogen atom, a halogen atom or a lower alkyl or alkoxy group optionally substituted with one or more halogen atoms, such as a trifluoromethyl group,B represents a hydrogen atom and D a hydroxyl group, or B and D simultaneously represent an oxygen atom,n represents 1 or 2, andR.sub.
    Type: Grant
    Filed: August 7, 1990
    Date of Patent: October 29, 1991
    Assignee: Science et Organization
    Inventors: Gerald Guillaumet, Christine Flouzat, Jacqueline Bonnet