Patents by Inventor G. Scott Lett

G. Scott Lett has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20220269763
    Abstract: The present invention extends to methods, systems, and computer program products for tailoring administration of aerosolized bioactive material. Aspects include communicating biological and subjective information to support formulation of personalized bioactive material compositions. Aerosolized bioactive materials can be administered to humans, via inhalation, using a vaporizer device which is engineered for real time data capture, and communication, with a software application and backend computational system. Smart vaporizer cartridges can be identified and their contents recalled. Based at least on contents, appropriate (e.g., precision) doses of bioactive material can be aerosolized and administered.
    Type: Application
    Filed: February 22, 2022
    Publication date: August 25, 2022
    Inventors: G. Scott Lett, Jeffrey Humpherys, Ruth Fisher, Chosen Lee, Caleb McClain
  • Publication number: 20140310635
    Abstract: A biological sample such as a tissue section is stained with one or more quantum dots and possibly other fluorophores (total number of fluorophores N). A camera coupled to a microscope generates an image of the specimen at a plurality of different wavelengths within the emission spectral band of the N fluorophores. An analysis module calculates coefficients C1 . . . CN at each pixel which are related to the concentration of each of the individual fluorophores. Morphological processing instructions find biological structures. A display module displays quantitative analysis results to the user. The quantitative analysis display includes histograms of the biological structures, scatter plots of fluorophore concentrations, statistical data, spectral data, image data and still others.
    Type: Application
    Filed: June 25, 2014
    Publication date: October 16, 2014
    Inventors: G. Scott Lett, Ned C. Haubein, Gary Pestano
  • Patent number: 8798394
    Abstract: A biological sample such as a tissue section is stained with one or more quantum dots and possibly other fluorophores (total number of fluorophores N). A camera coupled to a microscope generates an image of the specimen at a plurality of different wavelengths within the emission spectral band of the N fluorophores. An analysis module calculates coefficients C1 . . . CN at each pixel which are related to the concentration of each of the individual fluorophores. Morphological processing instructions find biological structures. A display module displays quantitative analysis results to the user. The quantitative analysis display includes histograms of the biological structures, scatter plots of fluorophore concentrations, statistical data, spectral data, image data and still others.
    Type: Grant
    Filed: April 24, 2012
    Date of Patent: August 5, 2014
    Assignee: Ventana Medical Systems, Inc.
    Inventors: G. Scott Lett, Ned C. Haubein, Gary Pestano
  • Patent number: 8290236
    Abstract: A biological sample such as a tissue section is stained with one or more quantum dots and possibly other fluorophores (total number of fluorophores N). A camera coupled to a microscope generates an image of the specimen at a plurality of different wavelengths within the emission spectral band of the N fluorophores. An analysis module calculates coefficients C1 . . . CN at each pixel from the set of images and reference spectral data for the N fluorophores. The coefficients C1 . . . CN are related to the concentration of each of the individual fluorophores at each pixel location. Morphological processing instructions find biological structures, e.g., cells, cellular components, genes, etc., in the images of the specimen. Quantitative analysis is performed on the identified biological structures. A display module displays the quantitative analysis results to the user, along with images of the specimen. The images can include images constructed from one or more of the coefficients C1 . . . CN.
    Type: Grant
    Filed: June 3, 2011
    Date of Patent: October 16, 2012
    Assignee: Ventana Medical Systems, Inc.
    Inventors: G. Scott Lett, Ned C. Haubein, Gary Pestano
  • Patent number: 8290235
    Abstract: A biological sample such as a tissue section is stained with one or more quantum dots and possibly other fluorophores (total number of fluorophores N). A camera coupled to a microscope generates an image of the specimen at a plurality of different wavelengths within the emission spectral band of the N fluorophores. An analysis module calculates coefficients C1 . . . CN at each pixel from the set of images and reference spectral data for the N fluorophores. The coefficients C1 . . . CN are related to the concentration of each of the individual fluorophores at each pixel location. Morphological processing instructions find biological structures, e.g., cells, cellular components, genes, etc., in the images of the specimen. Quantitative analysis is performed on the identified biological structures. A display module displays the quantitative analysis results to the user, along with images of the specimen. The images can include images constructed from one or more of the coefficients C1 . . . CN.
    Type: Grant
    Filed: June 3, 2011
    Date of Patent: October 16, 2012
    Assignee: Ventana Medical Systems, Inc
    Inventors: G. Scott Lett, Ned C. Haubein, Gary Pestano
  • Patent number: 8285024
    Abstract: A biological sample such as a tissue section is stained with one or more quantum dots and possibly other fluorophores (total number of fluorophores N). A camera coupled to a microscope generates an image of the specimen at a plurality of different wavelengths within the emission spectral band of the N fluorophores. An analysis module calculates coefficients C1 . . . CN at each pixel from the set of images and reference spectral data for the N fluorophores. The coefficients C1 . . . CN are related to the concentration of each of the individual fluorophores at each pixel location. Morphological processing instructions find biological structures, e.g., cells, cellular components, genes, etc., in the images of the specimen. Quantitative analysis is performed on the identified biological structures. A display module displays the quantitative analysis results to the user, along with images of the specimen. The images can include images constructed from one or more of the coefficients C1 . . . CN.
    Type: Grant
    Filed: June 3, 2011
    Date of Patent: October 9, 2012
    Assignee: Ventana Medical Systems, Inc.
    Inventors: G. Scott Lett, Ned C. Haubein, Gary Pestano
  • Patent number: 8280141
    Abstract: A biological sample such as a tissue section is stained with one or more quantum dots and possibly other fluorophores (total number of fluorophores N). A camera coupled to a microscope generates an image of the specimen at a plurality of different wavelengths within the emission spectral band of the N fluorophores. An analysis module calculates coefficients C1 . . . CN at each pixel from the set of images and reference spectral data for the N fluorophores. The coefficients C1 . . . CN are related to the concentration of each of the individual fluorophores at each pixel location. Morphological processing instructions find biological structures, e.g., cells, cellular components, genes, etc., in the images of the specimen. Quantitative analysis is performed on the identified biological structures. A display module displays the quantitative analysis results to the user, along with images of the specimen. The images can include images constructed from one or more of the coefficients C1 . . . CN.
    Type: Grant
    Filed: June 3, 2011
    Date of Patent: October 2, 2012
    Assignee: Ventana Medical Systems, Inc.
    Inventors: G. Scott Lett, Ned C. Haubein, Gary Pestano
  • Publication number: 20120224044
    Abstract: A biological sample such as a tissue section is stained with one or more quantum dots and possibly other fluorophores (total number of fluorophores N). A camera coupled to a microscope generates an image of the specimen at a plurality of different wavelengths within the emission spectral band of the N fluorophores. An analysis module calculates coefficients C1 . . . CN at each pixel which are related to the concentration of each of the individual fluorophores. Morphological processing instructions find biological structures. A display module displays quantitative analysis results to the user. The quantitative analysis display includes histograms of the biological structures, scatter plots of fluorophore concentrations, statistical data, spectral data, image data and still others.
    Type: Application
    Filed: April 24, 2012
    Publication date: September 6, 2012
    Inventors: G. Scott Lett, Ned C. Haubein, Gary Pestano
  • Patent number: 8244021
    Abstract: A biological sample such as a tissue section is stained with one or more quantum dots and possibly other fluorophores (total number of fluorophores N). A camera coupled to a microscope generates an image of the specimen at a plurality of different wavelengths within the emission spectral band of the N fluorophores. An analysis module calculates coefficients C1 . . . CN at each pixel from the set of images and reference spectral data for the N fluorophores. The coefficients C1 . . . CN are related to the concentration of each of the individual fluorophores at each pixel location. Morphological processing instructions find biological structures, e.g., cells, cellular components, genes, etc., in the images of the specimen. Quantitative analysis is performed on the identified biological structures. A display module displays the quantitative analysis results to the user, along with images of the specimen. The images can include images constructed from one or more of the coefficients C1 . . . CN.
    Type: Grant
    Filed: December 6, 2007
    Date of Patent: August 14, 2012
    Assignee: Ventana Medical Systems, Inc.
    Inventors: G. Scott Lett, Ned C. Haubein, Gary Pestano
  • Publication number: 20110235881
    Abstract: A biological sample such as a tissue section is stained with one or more quantum dots and possibly other fluorophores (total number of fluorophores N). A camera coupled to a microscope generates an image of the specimen at a plurality of different wavelengths within the emission spectral band of the N fluorophores. An analysis module calculates coefficients C1 . . . CN at each pixel from the set of images and reference spectral data for the N fluorophores. The coefficients C1 . . . CN are related to the concentration of each of the individual fluorophores at each pixel location. Morphological processing instructions find biological structures, e.g., cells, cellular components, genes, etc., in the images of the specimen. Quantitative analysis is performed on the identified biological structures. A display module displays the quantitative analysis results to the user, along with images of the specimen. The images can include images constructed from one or more of the coefficients C1 . . . CN.
    Type: Application
    Filed: June 3, 2011
    Publication date: September 29, 2011
    Inventors: G. Scott Lett, Ned C. Haubein, Gary Pestano
  • Publication number: 20110235879
    Abstract: A biological sample such as a tissue section is stained with one or more quantum dots and possibly other fluorophores (total number of fluorophores N). A camera coupled to a microscope generates an image of the specimen at a plurality of different wavelengths within the emission spectral band of the N fluorophores. An analysis module calculates coefficients C1 . . . CN at each pixel from the set of images and reference spectral data for the N fluorophores. The coefficients C1 . . . CN are related to the concentration of each of the individual fluorophores at each pixel location. Morphological processing instructions find biological structures, e.g., cells, cellular components, genes, etc., in the images of the specimen. Quantitative analysis is performed on the identified biological structures. A display module displays the quantitative analysis results to the user, along with images of the specimen. The images can include images constructed from one or more of the coefficients C1 . . . CN.
    Type: Application
    Filed: June 3, 2011
    Publication date: September 29, 2011
    Inventors: G. Scott Lett, Ned C. Haubein, Gary Pestano
  • Publication number: 20110235880
    Abstract: A biological sample such as a tissue section is stained with one or more quantum dots and possibly other fluorophores (total number of fluorophores N). A camera coupled to a microscope generates an image of the specimen at a plurality of different wavelengths within the emission spectral band of the N fluorophores. An analysis module calculates coefficients C1 . . . CN at each pixel from the set of images and reference spectral data for the N fluorophores. The coefficients C1 . . . CN are related to the concentration of each of the individual fluorophores at each pixel location. Morphological processing instructions find biological structures, e.g., cells, cellular components, genes, etc., in the images of the specimen. Quantitative analysis is performed on the identified biological structures. A display module displays the quantitative analysis results to the user, along with images of the specimen. The images can include images constructed from one or more of the coefficients C1 . . . CN.
    Type: Application
    Filed: June 3, 2011
    Publication date: September 29, 2011
    Inventors: G. Scott Lett, Ned C. Haubein, Gary Pestano
  • Publication number: 20110238325
    Abstract: A biological sample such as a tissue section is stained with one or more quantum dots and possibly other fluorophores (total number of fluorophores N). A camera coupled to a microscope generates an image of the specimen at a plurality of different wavelengths within the emission spectral band of the N fluorophores. An analysis module calculates coefficients C1 . . . CN at each pixel from the set of images and reference spectral data for the N fluorophores. The coefficients C1 . . . CN are related to the concentration of each of the individual fluorophores at each pixel location. Morphological processing instructions find biological structures, e.g., cells, cellular components, genes, etc., in the images of the specimen. Quantitative analysis is performed on the identified biological structures. A display module displays the quantitative analysis results to the user, along with images of the specimen. The images can include images constructed from one or more of the coefficients C1 . . . CN.
    Type: Application
    Filed: June 3, 2011
    Publication date: September 29, 2011
    Inventors: G. Scott Lett, Ned C. Haubein, Gary Pestano
  • Publication number: 20080212866
    Abstract: A biological sample such as a tissue section is stained with one or more quantum dots and possibly other fluorophores (total number of fluorophores N). A camera coupled to a microscope generates an image of the specimen at a plurality of different wavelengths within the emission spectral band of the N fluorophores. An analysis module calculates coefficients C1 . . . CN at each pixel from the set of images and reference spectral data for the N fluorophores. The coefficients C1 . . . CN are related to the concentration of each of the individual fluorophores at each pixel location. Morphological processing instructions find biological structures, e.g., cells, cellular components, genes, etc., in the images of the specimen. Quantitative analysis is performed on the identified biological structures. A display module displays the quantitative analysis results to the user, along with images of the specimen. The images can include images constructed from one or more of the coefficients C1 . . . CN.
    Type: Application
    Filed: December 6, 2007
    Publication date: September 4, 2008
    Inventors: G. Scott Lett, Ned C. Haubein, Gary Pestano