Patents by Inventor Gáspár NAGY

Gáspár NAGY has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHOD FOR INCREASING THE GALACTOSE CONTENT OF RECOMBINANT PROTEINS
    Publication number: 20220372157
    Abstract: The present invention relates to a method for increasing the galactose content of a recombinant protein produced in mammalian cells, wherein during the cultivation of said cells the pH of the cell culture is changed and a composition comprising nucleosides, transition metal salts and/or sugars is fed.
    Type: Application
    Filed: May 20, 2022
    Publication date: November 24, 2022
    Inventors: Ákos PUTICS, Dénes ZALAI, Gáspár NAGY, László PÁRTA, Áron SCHLEICHER
  • METHOD FOR MODIFYING THE GLYCOSYLATION PROFILE OF A RECOMBINANT GLYCOPROTEIN PRODUCED IN CELL CULTURE
    Publication number: 20220098634
    Abstract: The present invention relates to a method for modifying the glycosylation profile of a recombinant glycoprotein produced in cell culture comprising culturing eukaryotic cells expressing the recombinant glycoprotein in a cell culture medium, wherein the cell culture medium is supplemented with fucose, manganese, and taurine, wherein the glycosylation profile of the produced recombinant glycoprotein is modified to better resemble the glycosylation profile of a reference glycoprotein than when cultured without said supplementation.
    Type: Application
    Filed: November 6, 2019
    Publication date: March 31, 2022
    Inventors: László Párta, Ákos Putics, Tibor Balogh, Balázs Horváth, Gáspár Nagy
  • METHOD FOR INCREASING THE GALACTOSE CONTENT OF RECOMBINANT PROTEINS
    Publication number: 20180230228
    Abstract: The present invention relates to a method for increasing the galactose content of a recombinant protein produced in mammalian cells, wherein during the cultivation of said cells the pH of the cell culture is changed and a composition comprising nucleosides, transition metal salts and/or sugars is fed.
    Type: Application
    Filed: August 4, 2016
    Publication date: August 16, 2018
    Inventors: Ákos PUTICS, Dénes ZALAI, Gáspár NAGY, László PÁRTA, Áron SCHLEICHER