Patents by Inventor Ga Bi Lee

Ga Bi Lee has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methionyl tRNA synthetase for biosynthesis of photomethionine-labeled protein and method for preparing photoactive protein G variant using same
    Patent number: 9914757
    Abstract: Provided is a methionyl tRNA synthase (MRS) for the biosynthesis of a photomethionine-labeled protein and a method for preparing a photoactivatable protein G variant using same and, more particularly, to an MRS variant in which alanine at the position of 12th is substituted with glycine, leucine at the position of 13th by serine, tyrosine at the position of 260th by phenylalanine, isoleucine at the position of 297th by valine, and histidine at the position of 301st by leucine from the N-terminal of the amino acid sequence of a wild-type Escherichia coli methionyl tRNA synthase. The MRS variant effectively confirms the biosynthesis of a photomethionine (pM)-labeled target protein and thus can be utilized for the biosynthesis of a pM-labeled target protein.
    Type: Grant
    Filed: May 29, 2014
    Date of Patent: March 13, 2018
    Assignee: Korean Research Institute of Bioscience and Biotechnology
    Inventors: Myung Kyu Lee, Bong Hyun Chung, Jeong Hee Moon, Ga Bi Lee
  • METHIONYL TRNA SYNTHETASE FOR BIOSYNTHESIS OF PHOTOMETHIONINE-LABELED PROTEIN AND METHOD FOR PREPARING PHOTOACTIVE PROTEIN G VARIANT USING SAME
    Publication number: 20160200777
    Abstract: Provided is a methionyl tRNA synthase (MRS) for the biosynthesis of a photomethionine-labeled protein and a method for preparing a photoactivatable protein G variant using same and, more particularly, to an MRS variant in which alanine at the position of 12th is substituted with glycine, leucine at the position of 13th by serine, tyrosine at the position of 260th by phenylalanine, isoleucine at the position of 297th by valine, and histidine at the position of 301st by leucine from the N-terminal of the amino acid sequence of a wild-type Escherichia coli methionyl tRNA synthase. The MRS variant effectively confirms the biosynthesis of a photomethionine (pM)-labeled target protein and thus can be utilized for the biosynthesis of a pM-labeled target protein.
    Type: Application
    Filed: May 29, 2014
    Publication date: July 14, 2016
    Applicant: Korea Research Institute of Bioscience and Biotechnology
    Inventors: Myung Kyu Lee, Bong Hyun Chung, Jeong Hee Moon, Ga Bi Lee