Abstract: A method for preparing a nutritional multi-supplement complex, the method comprising: (i) preparing a dispersion of spheroidal polysaccharide-stabilized complexes comprising a water-soluble polysaccharide and at least one water-soluble nutritional supplement in an aqueous medium, wherein the water-soluble polysaccharide and water-soluble nutritional supplement are complexed with each other by ionic interactions in the spheroidal polysaccharide-stabilized complexes; (ii) preparing an oil-supplement solution comprising at least one oil-soluble nutritional supplement dissolved in a food grade oil; and (iii) blending the dispersion of spheroidal polysaccharide-stabilized complexes with the oil-supplement solution to produce the nutritional multi-supplement complex, wherein the nutritional multi-supplement complex comprises droplets of the oil-supplement solution encapsulated by the spheroidal polysaccharide-stabilized complexes.