Patents by Inventor Gabor Makara

Gabor Makara has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Acid amide derivatives and process for the preparation thereof
    Patent number: 5912245
    Abstract: The present invention is directed to an acid amide of the formula ##STR1## wherein R.sup.1 represents hydrogen or nitro,R.sup.2 and R.sup.3 stand for, independently from each other, hydrogen, lower alkyl or lower alkenyl each optionally carrying a substituent selected from the group consisting of halogen, hydroxy, lower alkoxy, di(lower alkyl)amino, phenyl-lower alkoxycarbonyl and a 5- to 6-membered saturated hetero-ring selected from the group consisting of piperidino, pyrrolidino, piperazino and morpholino; orR.sup.2 and R.sup.3 form, together with the adjacent nitrogen atom, a 6-membered saturated heterocyclic group selected from the group consisting of piperidino, pyrrolidino, piperazino and morpholino, said heterocyclic group optionally carrying a hydroxy or a hydroxy-lower alkyl group; or apharmaceutically acceptable salt thereof; process of making and pharmaceutical compositions and methods of treating.
    Type: Grant
    Filed: February 14, 1997
    Date of Patent: June 15, 1999
    Assignee: Egis Gyogyszergyar RT.
    Inventors: Endre Rivo, Szilveszter E. Vizi, Gabor Makara, Jozsef Reiter, Gabor Blasko, Gyula Simig, Laszlo Gaal, Marton Fekete
  • Analogs of growth hormone releasing factor (GRF) and a method for the preparation thereof
    Patent number: 5023322
    Abstract: The invention relates to new peptides of the formula ##STR1## wherein R.sup.2 represents Ala or D-Ala,R.sup.11 represents Arg or D-Arg,R.sup.13 represents Val or Ile,R.sup.15 represents Gly, Leu, Phe or a valence bond,R.sup.27 represents Met or Nle,R.sup.28 represents Ser, D-Ser or Asn, andY represents OH or NH.sub.2,and to salts thereof. These compounds stimulate the release of growth hormone and can be used in the therapy as well as for veterinary or animal husbandry purposes.
    Type: Grant
    Filed: August 30, 1989
    Date of Patent: June 11, 1991
    Assignee: MTA Kutatas-es Szervezetelemzo Intezete
    Inventors: Magdolna Kovacs, Judit Horvath, Sandor Vigh, Imre Mezo, Istvan Teplan, Balazs Szoke, Janos Seprodi, Zsolt Vadasz, Edit Hegedus, Gabor Makara, Gyorgy Rappay
  • Process for the preparation of angiotensin-II analogues substituted in the 1-, 5- and 8- positions
    Patent number: 4672054
    Abstract: The invention relates to octapeptides of the formulaX-Arg-Val-Tyr-Y-His-Pro-W (I)whereinX is a sarcosyl, lactoyl or hydroxyacetyl radical,Y is cyclopentylglycyl or cyclohexylglycyl, andW is an alanine radical or lactic acid radicalhaving angiotensine-II antagonistic activity.
    Type: Grant
    Filed: August 1, 1985
    Date of Patent: June 9, 1987
    Assignee: Richter Gedeon Vegyeszeti Gyar Rt.
    Inventors: Olga Nyeki nee Kuprina, Lajos Kisfaludy, Katalin Szeberenyi nee Szalay, Gabor Makara, Bertalan Varga, Egon Karpati, Laszlo Szporny