Abstract: Topical formulation containing pregabalin for long-term analgesic activity. The composition is prepared using high pressure homogenization, which changes the structure of the composition. The analgesic effect of the compounds of the present invention is significantly increased compared to reference formulations homogenized with equipment of the same quantitative composition but less shearing forces.

Abstract: The present invention relates to a topical pharmaceutical composition comprising pregabalin and a reduced micellar phospholipid as an active ingredient, which results in a prolonged analgesic effect of pregabalin. The product can reduce neuropathic pain by at least 5 hours.

Abstract: Topical formulation containing pregabalin for long-term analgesic activity. The composition is prepared using high shear mixers or homogenizers such as HPH or ultrasonic devices, which changes the structure of the composition. The analgesic effect of the compounds of the present invention is significantly increased compared to reference formulations homogenized with equipment of the same quantitative composition but less shearing forces.

Abstract: Embodiments disclosed herein relate to a thin, light, and portable system for measuring one or more parameters of a contact patch between a tire and a surface. The system may be configured with an array of sensors capable of being removable fixed to the surface. The array of sensors may measure the one or more parameters of the contact patch between the tire and the surface. Moreover, the system may include a scanner configured to interpret the measurements from the array of sensors as data and store the data.

Abstract: An endoscope includes a shaft having proximal and distal ends and a longitudinal axis therebetween. A handle is coupled to the proximal end of the shaft, and an image sensor is carried on the distal end of the shaft. A channel extends through at least a distal shaft portion and has a channel diameter, and a section of the channel is re-configurable between a constricted shape and a non-constricted shape to accommodate tools introduced therethrough. The combined diagonal dimension and channel diameter is usually greater than the outer shaft diameter. The image sensor may be connected to a connector on the housing by a first slack flex circuit and a lights source on the shaft may be connected to a connector on the housing by a second slack flex circuit.

Abstract: Embodiments disclosed herein relate to a thin, light, and portable system for measuring one or more parameters of a contact patch between a tire and a surface. The system may be configured with an array of sensors capable of being removable fixed to the surface. The array of sensors may measure the one or more parameters of the contact patch between the tire and the surface. Moreover, the system may include a scanner configured to interpret the measurements from the array of sensors as data and store the data.

Abstract: An endoscope includes a shaft having proximal and distal ends and a longitudinal axis therebetween. A handle is coupled to the proximal end of the shaft, and an image sensor is carried on the distal end of the shaft. A channel extends through at least a distal shaft portion and has a channel diameter, and a section of the channel is re-configurable between a constricted shape and a non-constricted shape to accommodate tools introduced therethrough. The combined diagonal dimension and channel diameter is usually greater than the outer shaft diameter. The image sensor may be connected to a connector on the housing by a first slack flex circuit and a lights source on the shaft may be connected to a connector on the housing by a second slack flex circuit.

Abstract: An endoscope includes a shaft having proximal and distal ends and a longitudinal axis therebetween. A handle is coupled to the proximal end of the shaft, and an image sensor is carried on the distal end of the shaft. A channel extends through at least a distal shaft portion and has a channel diameter, and a section of the channel is re-configurable between a constricted shape and a non-constricted shape to accommodate tools introduced therethrough. The combined diagonal dimension and channel diameter is usually greater than the outer shaft diameter. The image sensor may be connected to a connector on the housing by a first slack flex circuit and a lights source on the shaft may be connected to a connector on the housing by a second slack flex circuit.

Abstract: An endoscope includes a shaft having proximal and distal ends and a longitudinal axis therebetween. A handle is coupled to the proximal end of the shaft, and an image sensor is carried on the distal end of the shaft. A channel extends through at least a distal shaft portion and has a channel diameter, and a section of the channel is re-configurable between a constricted shape and a non-constricted shape to accommodate tools introduced therethrough. The combined diagonal dimension and channel diameter is usually greater than the outer shaft diameter. The image sensor may be connected to a connector on the housing by a first slack flex circuit and a lights source on the shaft may be connected to a connector on the housing by a second slack flex circuit.

Abstract: An endoscope includes a shaft having proximal and distal ends and a longitudinal axis therebetween. A handle is coupled to the proximal end of the shaft, and an image sensor is carried on the distal end of the shaft. A channel extends through at least a distal shaft portion and has a channel diameter, and a section of the channel is re-configurable between a constricted shape and a non-constricted shape to accommodate tools introduced therethrough. The combined diagonal dimension and channel diameter is usually greater than the outer shaft diameter. The image sensor may be connected to a connector on the housing by a first slack flex circuit and a lights source on the shaft may be connected to a connector on the housing by a second slack flex circuit.

Abstract: A portable power tool includes a drive motor configured to generate torque, a transmission including a plurality of transmission gears positioned in a housing and configured to transmit torque generated by the drive motor to a drive shaft, a first adjusting element positioned on the housing, and a first sensor configured to detect a position of the first adjusting element. The first adjusting element is configured to set at least one of the torque and a transmission gear of the plurality of transmission gears. The first sensor is configured to transmit a first signal corresponding to the position of the first adjusting element to an electronic control element.

Abstract: A method is provided to display an image frame sequence comprising: displaying an image frame sequence on a display screen; and in the course of displaying the image frame sequence, displaying a zooming user interface (ZUI) frame sequence on the display screen.

Abstract: An electric power tool, in particular a drill/screwdriver, has a drive motor which is coupled via a gearbox to an output drive element. The gearbox has a plurality of gears. In particular, the drive motor is coupled to a drive spindle in which the torque generated by the drive motor is adjustable. The torque can be adjusted by a first, manually operated, adjusting device, and by a second, manually operated, adjusting device. The second adjusting device is configured to adjust the torque by selecting the gear of the gearbox. Both adjusting devices are operated by a common actuating element.

Abstract: The invention relates to a catalyst according to the formula IrCl(cod)(NHC)]+nP (n=2, 3 or 4), or [Ir(cod)(NHC)(P)]+nP (n=1, 2 or 3), which is suitable to decompose formates in an aqueous reaction system, and for the production of hydrogen gas free of COx or hydrogenation of hydrogen carbonates, wherein Ir means iridium; Cl means chloro; cod means 1,5-cyclooctadiene; NHC means N-heterocyclic carbene, preferably 1-R-3-methylimidasolium chloride, wherein R means C1 to C5 alkyl and P means 1,3,5-triaza-7-phosphaadamantane (pta), monosulphonated triphenilphosphine (mtppms), trisulphonated triphenylphosphine (mtppts), or tetrasulphonated diphenylphosphynopropane (dpppts). Furthermore, the invention relates to a process for the preparation of the catalyst according to the invention.

Abstract: A method is provided to display an image frame sequence comprising: displaying an image frame sequence on a display screen; and in the course of displaying the image frame sequence, displaying a zooming user interface (ZUI) frame sequence on the display screen.

Abstract: A portable power tool includes a drive motor configured to generate torque, a transmission including a plurality of transmission gears positioned in a housing and configured to transmit torque generated by the drive motor to a drive shaft, a first adjusting element positioned on the housing, and a first sensor configured to detect a position of the first adjusting element. The first adjusting element is configured to set at least one of the torque and a transmission gear of the plurality of transmission gears. The first sensor is configured to transmit a first signal corresponding to the position of the first adjusting element to an electronic control element.

Abstract: An electric power tool, in particular a drill/screwdriver, has a drive motor which is coupled via a gearbox to an output drive element. The gearbox has a plurality of gears. In particular, the drive motor is coupled to a drive spindle in which the torque generated by the drive motor is adjustable. The torque can be adjusted by a first, manually operated, adjusting device, and by a second, manually operated, adjusting device. The second adjusting device is configured to adjust the torque by selecting the gear of the gearbox. Both adjusting devices are operated by a common actuating element.

Abstract: A hand-guided power tool having a rotating knob adjusting device provided with a knob part and rotatable between at least two adjustment positions spaced apart from each other in a circumferential direction, and means for securing the rotating knob adjusting device against an inadvertent rotation.