Abstract: A fluid connector system includes a first connector adjoining a second connector at a junction, and a sealing member coupled to the first connector and the second connector around the junction. The sealing member can include an annular wall having a first annular portion configured to engage the first connector and a second annular portion configured to engage the second connector. The sealing member can include an annular chamber extending between the first annular portion and the second annular portion. The annular chamber can be formed by the first annular portion sealing against an outer surface of the first connector and the second annular portion sealing against an outer surface of the second connector when a pressure between the sealing member and the first connector and the second connector is negative.

Abstract: Disclosed herein are systems and methods for providing targeted temperature management (TTM) therapy to a patient. Systems included herein provide an airflow to the patient in additional to a fluid flow that define a thermal energy exchange with the patient. Various systems may provide air at a defined TTM temperature to a thermal contact pad, a mattress or a ventilator that delivers the TTM air to the patient via the ventilation therapy. Also disclosed herein are systems, devices, and methods for preventing, managing, and/or removing perspiration moisture from between the thermal contact pad and the patient. Disclosed herein is a thermal contact pad includes a wicking material to draw moisture away from the patient. Disclosed herein also is a thermal contact pad including airflow that draws moisture away from the patient.

Abstract: Disclosed herein are medical systems, pads, and methods for exchanging thermal energy between a circulating fluid and a patient. Some pads are configured multiple uses on the same patient or across multiple different patients. Some pads include multiple layers of hydrogel disposed on one or both sides a fluid compartment. Removable hydrogel layers expose other hydrogel layers for subsequent uses of the pad. Removable storage liners encapsulate one or multiple hydrogel layers. Separation liners between adjacent hydrogel layers isolate the adjacent hydrogels from each other and removal of the separation liner extends the operational life a hydrogel layer. Adhesive patches secure the pads to the patient including adhesive patches extending through openings of a pad. Some pads are configured for disinfection, sterilization and/or laundering. In an embodiment, the fluid is air and a vacuum within a compartment of the pad secures the pad to the patient.

Abstract: Disclosed herein are systems and methods for providing targeted temperature management (TTM) therapy to a patient. Systems included herein provide an airflow to the patient in additional to a liquid flow that define a thermal energy exchange with the patient. Various systems may provide air at a defined TTM temperature to a thermal contact pad, a mattress or a ventilator that delivers the TTM air to the patient via the ventilation therapy. Also disclosed herein are systems, devices, and methods for preventing, managing, and/or removing perspiration moisture from between the thermal contact pad and the patient. Disclosed herein is a thermal contact pad includes a wicking material to draw moisture away from the patient. Disclosed herein also is a thermal contact pad including airflow that draws moisture away from the patient.

Abstract: Disclosed herein is a medical pad for exchanging thermal energy between a targeted temperature management (TTM) fluid and a patient. The medical pad includes a fluid containing layer configured for circulation of a TTM fluid therein. The pad is configured to expand together with an expansion of the patient's skin. A fluid containing layer of the pad includes openings extending therethrough to facilitate expansion. The pad further includes tabs extending away from a perimeter edge, so that a clinician may apply a lifting force to the tab to separate a proximate portion of the pad away from the patient. The pad further includes a hydrogel layer formed of an ultraviolet light-cured composition.

Abstract: A sealing member for providing a seal between fluid connectors includes a tubular member defining a lumen extending between a first end and a second end. The tubular member may receive a first connector via the first end and a second connector via the second end, and includes an annular wall extending between a first annular portion adjacent the first end and a second annular portion adjacent the second end. The first annular portion may engage the first connector, and the second annular portion may engage the second connector. When a pressure within the lumen is negative, atmospheric acting inward on the annular wall compresses the sealing member to define a contact force between the second annular portion and the second connector sufficient to define a fluid seal between the sealing member and the second connector.

Abstract: Disclosed herein a blanket apparatus and systems and methods pertaining to the same. The blanket includes a body portion formed of fabric, wherein the fabric is elastomer or elastomer-based and a first pocket within the body portion and surrounded by the fabric, wherein the first pocket is an enclosed area filled with an insulative material, and wherein the blanket is configured to be placed on at least a first thermal pad of a targeted temperature management (TTM) system, wherein the first pocket is configured to provide a weight on top of the first thermal pad. The insulative material may be an insulative gel, paste or granular material. In some instances, a length of the first pocket is substantially an entirety of a length of the blanket. Additionally, in some instances, a width of the first pocket is substantially an entirety of a width of the blanket.

Abstract: Disclosed are systems, pads, and methods for targeted temperature management. For example, a pad can include a multilayered pad body, a pad inlet connector, and a pad outlet connector. The pad body can include a conduit layer and a patient-interfacing layer over the conduit layer. The conduit layer can include one or more conduits configured to convey a temperature-controlled fluid as a supply fluid from a hydraulic system and a return fluid back to the hydraulic system. The patient-interfacing layer can be configured for placement on a portion of a patient's body. The patient-interfacing layer can have a patient-facing side including a plurality of wells configured to hold a thermally conductive medium. The pad inlet connector can include a pad inlet configured for charging the conduit layer with the supply fluid. The pad outlet connector can include a pad outlet configured for discharging the return fluid from the conduit layer.

Abstract: A system is disclosed for recommending a thermal pad set for use in providing a targeted temperature management (TTM) therapy to a patient, where the system includes a computer implemented method. The computer implemented method includes receiving a request for a thermal pad set recommendation from a clinician device, receiving a patient's identification from the clinician device, retrieving one or more patient parameter values from an electronic medical record for the patient, determining a pad set recommendation according to the patient parameter values in combination with a pad set correlation table, and displaying the pad set recommendation on the clinician device. Also disclosed herein is a system including a non-transitory computer-readable medium with instructions encoded thereon and one or more processors configured to, when executing the instructions, perform operations in accordance with processes of the computer implemented method.

Abstract: Disclosed herein are systems and methods for providing targeted temperature management (TTM) therapy to a patient. For example, TTM systems include a connection system for coupling a fluid deliver line to a thermal contact pad. The connection system is configured to provide indication to the user that the fluid deliver line is completely connected to thermal contact pad. In addition, the connection system also includes a controller for activating a connection lock and for sharing signals with a TTM system module. The fluid deliver line includes a pair of conduits arranged concentrically and the thermal pad includes a TTM fluid filter disposed within a fluid containing layer.

Abstract: A medical pad for exchanging thermal energy between a targeted temperature management (TTM) fluid and a patient. The medical pad includes a fluid containing layer configured for circulation of a TTM fluid therein. The pad may further include a bistable stiffening structure configured to transition between a first stable shape and a second stable shape. The pad may further include a thermally-conductive compressible foam layer disposed between the fluid containing layer and a patient contact side of the pad. a self-adhering stretchable band configured to secure the pad to the patient. The pad may further include a semi-permeable layer disposed between an underside of the fluid containing layer and a hydrogel layer so that the TTM fluid may migrate from the fluid containing layer to the hydrogel layer.

Abstract: Disclosed are systems, pads, and methods for targeted temperature management. A pad can include a multilayered pad body, a pad inlet connector, and a pad outlet connector. The pad body can include a plurality of separable longitudinal portions, wherein each longitudinal portion of the longitudinal portions includes a conduit, a patient-interfacing layer over the conduit, and an insulation layer over the conduit opposite the patient-interfacing layer. The conduit can be configured to convey a temperature-controlled fluid as a supply fluid from a hydraulic system or convey a return fluid back to the hydraulic system. The patient-interfacing layer can include a thermally conductive medium configured for placement on a patient’s body. The insulation layer can include an insulative foam. The pad inlet connector can be configured for charging the pad with the supply fluid while the pad outlet connector can be configured for discharging the return fluid from the pad.

Abstract: A sealing member for providing a seal between fluid connectors includes a tubular member defining a lumen extending between a first end and a second end. The tubular member may receive a first connector via the first end and a second connector via the second end, and includes an annular wall extending between a first annular portion adjacent the first end and a second annular portion adjacent the second end. The first annular portion may engage the first connector, and the second annular portion may engage the second connector. When a pressure within the lumen is negative, atmospheric acting inward on the annular wall compresses the sealing member to define a contact force between the second annular portion and the second connector sufficient to define a fluid seal between the sealing member and the second connector.

Abstract: Embodiments are directed to a fluid collection system for collecting and transporting urine away from the body. The system includes a fluid collection device positionable at least proximate to a urethra of a female user. The device includes a fluid impermeable enclosure, a fluid permeable membrane, a reservoir at least partially defined by the enclosure and the membrane, a porous body disposed in the reservoir, and a drain tube coupled to an intermediate region of the enclosure. The reservoir may be configured to receive fluid discharged from the user through the fluid permeable membrane. The tube may be positioned and configured to drain the fluid that flows through the porous body. The system further includes a vacuum source configured to draw fluid from the device by applying at least a partial suction force to the reservoir of the device and a fluid collection container in fluid communication with the tube.

Abstract: Disclosed herein are systems, pads, and methods for targeted temperature management. For example, a pad can include a multilayered pad body, a pad inlet connector, and a pad outlet connector. The pad body can include a conduit layer and a non-adhesive, thermally conductive layer over the conduit layer. The conduit layer can include one or more conduits configured to convey a temperature-controlled fluid as a supply fluid from a hydraulic system of a control module. The one-or-more conduits can also configured to convey the temperature-controlled fluid as a return fluid back to the hydraulic system. The conductive layer can be configured for placement on a portion of a patient's body. The pad inlet connector can include a pad inlet configured for charging the conduit layer with the supply fluid. The pad outlet connector can include a pad outlet configured for discharging the return fluid from the conduit layer.

Abstract: Disclosed are fluid delivery lines (“FDLs”) of systems, pads, and methods for targeted temperature management. A system can include a control module, a primary FDL, a secondary FDL, and one or more pads for placement on one or more portions of a patient's body, respectively. The primary FDL can be configured to convey a temperature-controlled fluid as a supply fluid from a hydraulic system of the control module and convey a return fluid back to the hydraulic system. Each pad of the one-or-more pads can include a multilayered pad body including a conduit layer configured to convey the supply fluid therethrough. The secondary FDL can be configured to convey the supply fluid from the primary FDL and convey the return fluid back to the primary FDL. The secondary FDL can include a pair of piercing tips configured to pierce the primary tubing for fluidly connecting the primary and secondary FDLs.

Abstract: Disclosed are systems and methods for performing targeted temperature management including a thermal pad having a thermoelectric device. A pad controller may regulate the temperature of the thermal pad. The thermal pad temperature can facilitate cooling and/or warming of the patient. The pad can include a thermal conduction layer and a skin contact layer. The system may include a controller to set the pad temperature of multiple thermal pads according to a TTM therapy. The thermal pad and the system can incorporate data from temperature sensors coupled to the thermoelectric device and the patient. The system controller may be coupled to the thermal pads via a wired or wireless connection.

Abstract: Disclosed are indicators for confirming fluid connections in systems, pads, and methods thereof for targeted temperature management. For example, a pad can include a multilayered pad body, a pad inlet connector, a pad outlet connector, and an indicator for visual indication of charging a conduit layer of the pad body with a supply fluid and confirmation of accurate fluid connections. The conduit layer includes one or more conduits for conveying a temperature-controlled fluid as the supply fluid from a hydraulic system of a control module as well as convey a return fluid back to the hydraulic system. A thermally conductive adhesive layer over the conduit layer is for placement on a portion of a patient's body. The pad inlet connector includes a pad inlet for charging the conduit layer with the supply fluid. The pad outlet connector includes a pad outlet for discharging the return fluid from the conduit layer.

Abstract: Disclosed herein are systems, pads, and methods thereof for targeted temperature management. In an example, a pad for targeted temperature management can include a pad body, a conduit system, one or more inlets, and one or more outlets. The pad body can be of a conformable material configured to conform to a body of a patient on the pad. The conduit system can be disposed in the pad body or an overlayer configured for placement over the pad body. The conduit system can include one or more conduits configured to convey a fluid through the pad body or the overlayer. The one-or-more inlets can be configured for charging the conduit system with the fluid, while the one-or-more outlets can be configured for discharging the fluid from the conduit system. Methods of the systems and pads can include methods of use. In another example, a deformable pad can be configured for receiving a neonatal patient.

Abstract: Disclosed herein are systems, pads, and methods thereof for targeted temperature management. A first pad can include a multilayered pad body and an inflatable cuff around the pad body. The pad body can include a conformable layer, a conduit layer over the conformable layer, and an insulation layer over the conduit layer. The conformable layer can include a conformable material configured to conform around a limb of a patient. The conduit layer can include one or more conduits configured to convey a fluid through the conduit layer. The insulation layer can be configured to insulate the conduit layer from an ambient temperature of an environment around the patient. The inflatable cuff can be configured to press the pad body against the limb of the patient when the inflatable cuff is inflated. Methods of the systems and pads can include methods of use.