Patents by Inventor Gabriel Akerele

Gabriel Akerele has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Poultry vaccine for clostridium perfringens
    Patent number: 11524061
    Abstract: The present disclosure relates to nanoparticle compositions for use as vaccines against Clostridium perfringens in poultry which causes necrotic enteritis in poultry. Such compositions include one or more Clostridium perfringens extracellular proteins entrapped in a polyanhydride or chitosan nanoparticle. The one or more Clostridium perfringens extracellular proteins may include one or more Clostridium perfringens toxins, such as, for example, alpha toxin (CPA), beta toxin (CPB), epsilon toxin (ETX), iota toxin (ITX), perfringolysin O (PFO), enterotoxin (CPE), beta2 toxin (CPB2), or NetB toxin. In some aspects, the composition further includes a Salmonella enteritidis flagellar protein. The present invention also includes methods for the oral delivery of one or more Clostridium perfringens extracellular proteins to the mucosal membrane of the intestinal tract of a bird of the order Galliformes.
    Type: Grant
    Filed: February 4, 2021
    Date of Patent: December 13, 2022
    Assignees: UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC, THE OHIO STATE UNIVERSITY
    Inventors: Ramesh Kumar Selvaraj, Gabriel Akerele, Sankar Renu, Renukaradhya J. Gourapura
  • POULTRY VACCINE FOR CLOSTRIDIUM PERFRINGENS
    Publication number: 20210236617
    Abstract: The present disclosure relates to nanoparticle compositions for use as vaccines against Clostridium perfringens in poultry which causes necrotic enteritis in poultry. Such compositions include one or more Clostridium perfringens extracellular proteins entrapped in a polyanhydride or chitosan nanoparticle. The one or more Clostridium perfringens extracellular proteins may include one or more Clostridium perfringens toxins, such as, for example, alpha toxin (CPA), beta toxin (CPB), epsilon toxin (ETX), iota toxin (ITX), perfringolysin O (PFO), enterotoxin (CPE), beta2 toxin (CPB2), or NetB toxin. In some aspects, the composition further includes a Salmonella enteritidis flagellar protein. The present invention also includes methods for the oral delivery of one or more Clostridium perfringens extracellular proteins to the mucosal membrane of the intestinal tract of a bird of the order Galliformes.
    Type: Application
    Filed: February 4, 2021
    Publication date: August 5, 2021
    Inventors: Ramesh Kumar Selvaraj, Gabriel Akerele, Sankar Renu, Renukaradhya J. Gourapura