Patents by Inventor Gabriel Corfas

Gabriel Corfas has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • TREATMENTS FOR NEUROPATHY
    Publication number: 20160058749
    Abstract: Small fiber neuropathy is treated or prevented by topically administering to a subject in need thereof topically active quinoline compounds or pharmaceutically acceptable salts thereof under conditions effective to treat or prevent neuropathy in the subject. Glial cell-derived neurotrophic factor (GDNF) receptors are modulated with the subject active quinoline compounds, which may be formulated in topical lotions.
    Type: Application
    Filed: November 9, 2015
    Publication date: March 3, 2016
    Inventors: Gabriel Corfas, Joshua C. Murtie
  • COMPOSITIONS AND METHODS FOR TREATING NEUROPATHY
    Publication number: 20160045487
    Abstract: The invention features XIB4035 for the treatment of large fiber neuropathy, and combinations of XIB4035 and GDNF for the treatment of both large and small fiber neuropathies.
    Type: Application
    Filed: March 26, 2014
    Publication date: February 18, 2016
    Inventor: Gabriel Corfas
  • Treatments for Neuropathy
    Publication number: 20110086878
    Abstract: Small fiber neuropathy is treated or prevented by topically administering to a subject in need thereof topically active quinoline compounds or pharmaceutically acceptable salts thereof under conditions effective to treat or prevent neuropathy in the subject. Glial cell-derived neurotrophic factor (GDNF) receptors are modulated with the subject active quinoline compounds, which may be formulated in topical lotions.
    Type: Application
    Filed: December 16, 2010
    Publication date: April 14, 2011
    Inventors: Gabriel Corfas, Joshua C. Murtie
  • Treatments for neuropathy
    Patent number: 7863295
    Abstract: Small fiber neuropathy is treated by topically administering to a subject in need thereof topically active quinoline compounds or pharmaceutically acceptable salts thereof under conditions effective to treat neuropathy in the subject. Glial cell-derived neurotrophic factor (GDNF) receptors are modulated with the subject active quinoline compounds, which may be formulated in topical lotions.
    Type: Grant
    Filed: January 8, 2009
    Date of Patent: January 4, 2011
    Assignee: Children's Medical Center Corporation
    Inventors: Gabriel Corfas, Joshua C. Murtie
  • TREATMENTS FOR NEUROPATHY
    Publication number: 20090203735
    Abstract: Small fiber neuropathy is treated or prevented by topically administering to a subject in need thereof topically active quinoline compounds or pharmaceutically acceptable salts thereof under conditions effective to treat or prevent neuropathy in the subject. Glial cell-derived neurotrophic factor (GDNF) receptors are modulated with the subject active quinoline compounds, which may be formulated in topical lotions.
    Type: Application
    Filed: January 8, 2009
    Publication date: August 13, 2009
    Inventors: Gabriel Corfas, Joshua C. Murtie
  • Neurotrophic factor
    Patent number: 5665862
    Abstract: The invention pertains to isolated neurotrophic factors, designated as ARIA, which are able to induce the formation of ion channels in a surface membrane of a cell. The amino acid sequence of the neurotrophic factors includes an EGF-like domain, and a second amino acid sequence encoded by at least a portion of an exon of the neurotrophic factor gene normally expressed in a neuronal cell, especially a nerve cell. The neurotrophic factor is distinct from, and essentially unrelated to, the chicken prion-like protein previously identified.
    Type: Grant
    Filed: December 15, 1993
    Date of Patent: September 9, 1997
    Assignee: President and Fellows of Harvard College
    Inventors: Gerald D. Fischbach, Douglas L. Falls, Kenneth M. Rosen, Gabriel Corfas