Abstract: The present application relates to a device, system, and method for determining patient body temperature based on a multi-modal wearable biosensor applied to the surface of the body that measures multiple physiological, physical, and skin-surface/microclimatic thermal parameters, derives additional instantaneous parameters, learns contextual parameters based on temporal dynamics, and employs ensemble model fusion method to estimate core body temperature.

Abstract: A wireless wearable sensor device, system, method, and non-transitory computer readable medium for screening for structural heart disease based on electrocardiogram, phonocardiogram, and/or accelerometer signals on a patient's skin surface.

Abstract: A wireless wearable sensor device, system, method, and non-transitory computer readable medium for screening for structural heart disease based on electrocardiogram, phonocardiogram, and/or accelerometer signals on a patient's skin surface.

Abstract: A method and system of a scalable modular architecture for enabling clinicians to define clinical inputs, operators, and notifications on a per patient and enterprise basis for screening any pathological condition per the clinical practice

Abstract: A method and system for detecting pacing pulses originating from implanted pacemaker using surface Electrocardiogram (ECG) signals measured at a relatively low sampling rate and also rejecting the pacing artifacts from the recorded surface ECG signals.

Abstract: The present application relates to a device, system, and method for determining patient body temperature based on a multi-modal wearable biosensor applied to the surface of the body that measures multiple physiological, physical, and skin-surface/microclimatic thermal parameters, derives additional instantaneous parameters, learns contextual parameters based on temporal dynamics, and employs ensemble model fusion method to estimate core body temperature.

Abstract: A method and system for detecting pacing pulses originating from implanted pacemaker using surface Electrocardiogram (ECG) signals measured at a relatively low sampling rate and also rejecting the pacing artifacts from the recorded surface ECG signals.

Abstract: Various methods and systems are related to pulse-based automatic gain control. In one example, pulse-based automatic gain control (AGC) includes a variable gain amplifier (VGA) configured to amplify an analog input signal to generate an analog output signal based upon an amplification control signal; an integrate-and-fire (IF) sampler configured to generate a pulse train corresponding to the analog output signal; and a gain adjustment configured to generate the amplification control signal based upon a comparison of time between pulses of the pulse train to a reference time. In another example, a method includes determining time between pulses of a pulse train corresponding to an analog output signal from a VGA; generating an amplification control signal based upon a comparison of the time between pulses of the pulse train to a reference time; and adjusting amplification of the VGA in response to the amplification control signal.

Abstract: A wireless wearable sensor device, method, and non-transitory computer readable medium for determining patient body temperature based on a skin temperature and sensor ambient air temperature is disclosed.

Abstract: Various examples of devices, methods and systems related to pulse based arithmetic units. In one example, a pulse domain device includes an augend area calculator to provide an augend area output for an augend pulse train; an addend area calculator to provide an addend area output for an addend pulse train; a resultant sum area (RSA) decoder to provide a RSA output using the augend and addend area outputs; and a pulse timing calculator to provide RSA output pulse timing. In another example, a pulse domain device includes a multiplicand area calculator to provide an multiplicand area output for a multiplicand pulse train; a multiplier area calculator to provide a multiplier area output for a multiplier pulse train; a resultant product area (RPA) decoder to provide a RPA output using the multiplicand and multiplier area outputs; and a pulse timing calculator to provide RPA output pulse timing.

Abstract: A wireless wearable sensor device, system, method, and non-transitory computer readable medium for screening for structural heart disease based on electrocardiogram, phonocardiogram, and/or accelerometer signals on a patient's skin surface.

Abstract: Various methods and systems are related to pulse-based automatic gain control. In one example, pulse-based automatic gain control (AGC) includes a variable gain amplifier (VGA) configured to amplify an analog input signal to generate an analog output signal based upon an amplification control signal; an integrate-and-fire (IF) sampler configured to generate a pulse train corresponding to the analog output signal; and a gain adjustment configured to generate the amplification control signal based upon a comparison of time between pulses of the pulse train to a reference time. In another example, a method includes determining time between pulses of a pulse train corresponding to an analog output signal from a VGA; generating an amplification control signal based upon a comparison of the time between pulses of the pulse train to a reference time; and adjusting amplification of the VGA in response to the amplification control signal.

Abstract: Various examples of devices, methods and systems related to pulse based arithmetic units. In one example, a pulse domain device includes an augend area calculator to provide an augend area output for an augend pulse train; an addend area calculator to provide an addend area output for an addend pulse train; a resultant sum area (RSA) decoder to provide a RSA output using the augend and addend area outputs; and a pulse timing calculator to provide RSA output pulse timing. In another example, a pulse domain device includes a multiplicand area calculator to provide an multiplicand area output for a multiplicand pulse train; a multiplier area calculator to provide a multiplier area output for a multiplier pulse train; a resultant product area (RPA) decoder to provide a RPA output using the multiplicand and multiplier area outputs; and a pulse timing calculator to provide RPA output pulse timing.

Abstract: Various examples are provided for automation of QRS detection. In one example, among others, a system includes an integrate and fire (IF) sampler that can generate an IF pulse train from an analog input signal, and decision logic circuitry that can determine whether a QRS complex waveform is present in a pulse segment of the IF pulse train. In another example, a method includes generating an integrate and fire (IF) pulse train from an analog input signal, identifying a pulse segment of the IF pulse train, and determining whether a QRS waveform is present in the pulse segment based at least in part upon attributes associated with the pulse segment.

Abstract: Various examples are provided for automation of QRS detection. In one example, among others, a system includes an integrate and fire (IF) sampler that can generate an IF pulse train from an analog input signal, and decision logic circuitry that can determine whether a QRS complex waveform is present in a pulse segment of the IF pulse train. In another example, a method includes generating an integrate and fire (IF) pulse train from an analog input signal, identifying a pulse segment of the IF pulse train, and determining whether a QRS waveform is present in the pulse segment based at least in part upon attributes associated with the pulse segment.