Patents by Inventor Gabriel Nunez

Gabriel Nunez has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Inhibition of enteric infection through the modulation of microbiota
    Patent number: 11883444
    Abstract: Provided herein are compositions and methods for the inhibition of enteric infection. In particular, compositions comprising bacteria of the class Clostridia are administered to human and/or animal subjects to prevent or decrease susceptibility to enteric infection.
    Type: Grant
    Filed: July 15, 2022
    Date of Patent: January 30, 2024
    Assignee: The University of Chicago
    Inventors: Cathyrn R. Nagler, Gabriel Nunez, Yun-Gi Kim
  • METHODS AND COMPOSITIONS FOR INTESTINAL INFLAMMATION
    Publication number: 20230364162
    Abstract: Provided herein are compositions and methods for the management of intestinal inflammation. In particular, compositions comprising modified adherent-invasive E. coli (AIEC) are administered to human and/or animal subjects to treat, prevent or decrease susceptibility to intestinal inflammation.
    Type: Application
    Filed: September 28, 2021
    Publication date: November 16, 2023
    Inventors: Masashi Ohno, Gabriel Nunez, Naohiro Inohara, Mizuho Hasegawa
  • INHIBITION OF ENTERIC INFECTION THROUGH THE MODULATION OF MICROBIOTA
    Publication number: 20230158085
    Abstract: Provided herein are compositions and methods for the inhibition of enteric infection. In particular, compositions comprising bacteria of the class Clostridia are administered to human and/or animal subjects to prevent or decrease susceptibility to enteric infection.
    Type: Application
    Filed: July 15, 2022
    Publication date: May 25, 2023
    Inventors: Cathyrn R. Nagler, Gabriel Nunez, Yun-Gi Kim
  • Development of new monoclonal antibodies recognizing human prostate-specific membrane antigen (PSMA)
    Patent number: 11400121
    Abstract: Provided herein are compositions and methods for the inhibition of enteric infection. In particular, compositions comprising bacteria of the class Clostridia are administered to human and/or animal subjects to prevent or decrease susceptibility to enteric infection.
    Type: Grant
    Filed: January 5, 2018
    Date of Patent: August 2, 2022
    Assignee: THE UNIVERSITY OF CHICAGO
    Inventors: Cathryn R. Nagler, Gabriel Nunez, Yun-Gi Kim
  • TREATMENT OF STAPHYLOCOCCAL DISORDERS
    Publication number: 20220048979
    Abstract: Materials and methods are provided for treatment and/or prevention of Staphylococcal diseases and disorders such as infection and dermal inflammation.
    Type: Application
    Filed: October 22, 2021
    Publication date: February 17, 2022
    Inventors: Gabriel Nunez, Jon Oscherwitz, Kemp Cease, Yumi Nakamura, Tyler Nygaard
  • Treatment of staphylococcal disorders
    Patent number: 11198724
    Abstract: Materials and methods are provided for treatment and/or prevention of Staphylococcal diseases and disorders such as infection and dermal inflammation.
    Type: Grant
    Filed: March 14, 2014
    Date of Patent: December 14, 2021
    Assignee: THE REGENTS OF THE UNIVERSITY OF MICHIGAN
    Inventors: Gabriel Nunez, Jon Oscherwitz, Kemp Cease, Yumi Nakamura, Tyler Nygaard
  • DEVELOPMENT OF NEW MONOCLONAL ANTIBODIES RECOGNIZING HUMAN PROSTATE-SPECIFIC MEMBRANE ANTIGEN (PSMA)
    Publication number: 20190388483
    Abstract: Provided herein are compositions and methods for the inhibition of enteric infection. In particular, compositions comprising bacteria of the class Clostridia are administered to human and/or animal subjects to prevent or decrease susceptibility to enteric infection.
    Type: Application
    Filed: January 5, 2018
    Publication date: December 26, 2019
    Inventors: Cathym R. Nagler, Gabriel Nunez, Yun-Gi Kim
  • TREATMENT OF STAPHYLOCOCCAL DISORDERS
    Publication number: 20160031973
    Abstract: Materials and methods are provided for treatment and/or prevention of Staphylococcal diseases and disorders such as infection and dermal inflammation.
    Type: Application
    Filed: March 14, 2014
    Publication date: February 4, 2016
    Applicant: The Regents of the University of Michigan
    Inventors: Gabriel Nunez, Jon Oscherwitz, Kemp Cease, Yumi Nakamura, Tyler Nygaard
  • Modulators Of NOD2 Signalling
    Publication number: 20080280367
    Abstract: The present invention relates to intracellular signaling molecules, in particular the Nod2 protein and nucleic acids encoding the Nod2 protein. The present invention provides methods of identifying modulators of Nod2 signaling. In particular, the present invention additionally provides methods of screening immune modulators such as adjuvants using Nod2. The present invention further provides methods of altering Nod2 signaling.
    Type: Application
    Filed: March 26, 2008
    Publication date: November 13, 2008
    Applicant: THE REGENTS OF THE UNIVERSITY OF MICHIGAN
    Inventors: Gabriel Nunez, Naohiro Inohara, Yasunori Ogura
  • Modulators of Nod2 signaling
    Patent number: 7375086
    Abstract: The present invention relates to intracellular signaling molecules, in particular the Nod2 protein and nucleic acids encoding the Nod2 protein. The present invention provides methods of identifying modulators of Nod2 signaling. In particular, the present invention additionally provides methods of screening immune modulators such as adjuvants using Nod2. The present invention further provides methods of altering Nod2 signaling.
    Type: Grant
    Filed: January 12, 2006
    Date of Patent: May 20, 2008
    Assignee: The Regents of the University of Michigan
    Inventors: Gabriel Nuñez, Naohiro Inohara, Yasunori Ogura
  • Methods and compositions for mediation of immune responses and adjuvant activity
    Publication number: 20080008652
    Abstract: The present invention relates to methods and compositions for modulating immune responses and adjuvant activity. In particular, the present invention provides methods and compositions for screening for compounds that modulate cryopyrin signaling.
    Type: Application
    Filed: January 10, 2007
    Publication date: January 10, 2008
    Applicant: The Regents of the University of Michigan
    Inventors: Gabriel Nunez, Thirumala-Devi Kanneganti
  • Method of screening modulators of Nod1 signaling
    Patent number: 7244557
    Abstract: The present invention relates to intracellular signaling molecules, in particular the Nod1 protein. The present invention provides methods of identifying modulators of Nod1 signaling. The present invention further provides methods of altering Nod1 signaling.
    Type: Grant
    Filed: May 14, 2004
    Date of Patent: July 17, 2007
    Assignee: Regents of the University of Michigan
    Inventors: Gabriel Nuñez, Naohiro Inohara
  • RICK3 nucleic acids and proteins
    Patent number: 7176019
    Abstract: The present invention related to methods and compositions for modulating cellular signaling. In particular, the present invention relates to PKK and RICK3 proteins. The present invention further relates the to use of PKK and RICK3 proteins in modulating NF-?B signaling. The present invention thus provides novel targets for drug screening and therapeutics.
    Type: Grant
    Filed: December 22, 2005
    Date of Patent: February 13, 2007
    Assignee: The Regents of the University of Michigan
    Inventors: Gabriel Nuñez, Naohiro Inohara, Akihiro Muto
  • NOD nucleic acids and polypeptides
    Publication number: 20060292590
    Abstract: The present invention relates to the NOD proteins and nucleic acids encoding the NOD proteins. The present invention further provides assays for the detection of NOD polymorphisms and mutations associated with disease states, as well as methods of screening for ligands and modulators of NOD proteins.
    Type: Application
    Filed: January 26, 2006
    Publication date: December 28, 2006
    Inventors: Naohiro Inohara, Gabriel Nunez
  • Modulators of Nod2 signaling
    Publication number: 20060160118
    Abstract: The present invention relates to intracellular signaling molecules, in particular the Nod2 protein and nucleic acids encoding the Nod2 protein. The present invention provides methods of identifying modulators of Nod2 signaling. In particular, the present invention additionally provides methods of screening immune modulators such as adjuvants using Nod2. The present invention further provides methods of altering Nod2 signaling.
    Type: Application
    Filed: January 12, 2006
    Publication date: July 20, 2006
    Inventors: Gabriel Nunez, Naohiro Inohara, Yasunori Ogura
  • Nod2 nucleic acids and proteins
    Patent number: 7060493
    Abstract: The present invention relates to intracellular signalling molecules, in particular the Nod2 protein and nucleic acids encoding the Nod2 protein. The present invention provides isolated nucleotide sequence encoding Nod2, isolated Nod2 peptides, antibodies that specifically bind Nod2, methods for the detection of Nod2, and methods for screening compounds for the ability to alter Nod2 associated signal transduction.
    Type: Grant
    Filed: November 9, 2004
    Date of Patent: June 13, 2006
    Assignee: Regents of the University of Michigan
    Inventors: Gabriel Nunez, Naohiro Inohara, Yasunori Ogura
  • Modulators on Nod2 signaling
    Patent number: 7060442
    Abstract: The present invention relates to intracellular signaling molecules, in particular the Nod2 protein and nucleic acids encoding the Nod2 protein. The present invention provides methods of identifying modulators of Nod2 signaling. In particular, the present invention additionally provides methods of screening immune modulators such as adjuvants using Nod2. The present invention further provides methods of altering Nod2 signaling.
    Type: Grant
    Filed: December 9, 2002
    Date of Patent: June 13, 2006
    Assignee: Regents of the University of Michigan
    Inventors: Gabriel Nuñez, Naohiro Inohara, Yasunori Ogura
  • RICK3 nucleic acids and proteins
    Publication number: 20060105413
    Abstract: The present invention related to methods and compositions for modulating cellular signaling. In particular, the present invention relates to PKK and RICK3 proteins. The present invention further relates the to use of PKK and RICK3 proteins in modulating NF-?B signaling. The present invention thus provides novel targets for drug screening and therapeutics.
    Type: Application
    Filed: December 22, 2005
    Publication date: May 18, 2006
    Inventors: Gabriel Nunez, Naohiro Inohara, Akihiro Muto
  • NOD nucleic acids and polypeptides
    Patent number: 7041491
    Abstract: The present invention relates to the NOD proteins and nucleic acids encoding the NOD proteins. The present invention further provides assays for the detection of NOD polymorphisms and mutations associated with disease states, as well as methods of screening for ligands and modulators of NOD proteins.
    Type: Grant
    Filed: March 5, 2004
    Date of Patent: May 9, 2006
    Assignee: Regents of the University of Michigan
    Inventors: Naohiro Inohara, Gabriel Nuñez
  • NOD2 nucleic acids and proteins
    Publication number: 20050239105
    Abstract: The present invention relates to intracellular signalling molecules, in particular the Nod2 protein and nucleic acids encoding the Nod2 protein. The present invention provides isolated nucleotide sequence encoding Nod2, isolated Nod2 peptides, antibodies that specifically bind Nod2, methods for the detection of Nod2, and methods for screening compounds for the ability to alter Nod2 associated signal transduction.
    Type: Application
    Filed: November 9, 2004
    Publication date: October 27, 2005
    Inventors: Gabriel Nunez, Naohiro Inohara, Yasunori Ogura