Abstract: A fastening system and a deployment system for controlling translation and rotation of a deployment device are presented. A fastening system may comprise one or more components configured for arresting or restricting translation of a delivery catheter of a medical device, including a mitral valve fixation device such as the MitraClip®. A deployment system may comprise one or more components configured for locking rotation of a crimping cam to a slider to control deployment of a mitral valve fixation device.

Abstract: A fastening system and a deployment system for controlling translation and rotation of a deployment device are presented. A fastening system may comprise one or more components configured for arresting or restricting translation of a delivery catheter of a medical device, including a mitral valve fixation device such as the MitraClip®. A deployment system may comprise one or more components configured for locking rotation of a crimping cam to a slider to control deployment of a mitral valve fixation device.

Abstract: A device configured to cut leaflet tissue at a cardiac valve may comprise a guide catheter having a proximal end and a distal end, the guide catheter being positionable at a cardiac valve. The device may further include a cutting mechanism routable through the guide catheter and configured to extend from the distal end of the guide catheter, the cutting mechanism configured to cut a portion of leaflet tissue of the cardiac valve. Finally, the device may comprise a handle coupled to the proximal end of the guide catheter, the handle comprising at least one control operatively connected to the cutting mechanism such that the at least one control is configured to provide selective actuation of the cutting mechanism.

Abstract: A system configured to detach an interventional implant from a cardiac valve includes a guide catheter and a capture mechanism routable through the guide catheter. The capture mechanism comprises a capture hypotube with a container portion/space configured to receive an interventional implant connected to cardiac valve tissue. The capture mechanism also includes a cutting arm axially moveable relative to the capture hypotube. The capture hypotube and the cutting arm each include cutting elements that are brought together upon actuation of the cutting arm to thereby cut the cardiac valve tissue surrounding the interventional implant to free the implant from the cardiac valve.