Abstract: A temperature-controlled musical instrument carrying case for storing a musical instrument is provided. The musical instrument carrying case includes an insulated outer housing and an interior storage compartment that can store the musical instrument. In addition, the musical instrument carrying case includes a temperature sensitive device, a power source, a controller, and a heat-transfer device. The temperature sensitive device provides an indication of a temperature in the interior storage compartment to the controller. Based on the indication of the temperature, the controller generates and transmits a drive signal to the heat-transfer device. The heat-transfer device receives the drive signal from the controller and, based on the drive signal, at least selectively cools the interior storage compartment.