Patents by Inventor Gabriela G. Loots

Gabriela G. Loots has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • SYNTHETIC ANTIMICROBIAL MINERAL COMPOSITIONS, METHODS OF MAKING AND USING SAME
    Publication number: 20220000912
    Abstract: Provided herein are pharmaceutical compositions comprising a Fe2+-exchanged fluorinated synthetic smectite and a synthetic semiconducting metal sulfide. The compositions can be used to treat topical conditions and gastrointestinal ailments, and can be incorporated into wound dressings, hydrogels, personal protective equipment, and 3D printed articles. Also provided are methods of synthesizing the Fe2+-exchanged fluorinated synthetic smectite and methods of making the synthetic semiconducting metal sulfide.
    Type: Application
    Filed: June 25, 2021
    Publication date: January 6, 2022
    Inventors: Keith David Morrison, Gabriela G. Loots, Ty James Samo, Kelly Anne Martin
  • Compositions and methods for altering bone density and bone patterning
    Publication number: 20090017008
    Abstract: By exploiting cross-species sequence comparisons with in vitro and in vivo enhancer assays we were able to identify enhancer elements that drives human SOST expression in the adult mouse skeleton, and discovered a novel function for sclerostin during limb development. The enhancer elements and reagents described in the present invention facilitate the methods for development of products and methods to increase the mineral content of bone, which can consequently be utilized to treat a wide variety of bone related conditions, including, osteopenia, osteoporosis, fractures and other disorders in which low bone mineral density are the main cause of the disease as well as sclerosteosis, Van Buchem disease and other related disorders of the skeleton.
    Type: Application
    Filed: December 10, 2007
    Publication date: January 15, 2009
    Applicant: The Regents of the University of California
    Inventors: Gabriela G. Loots, Edward M. Rubin
  • Coordinate cytokine regulatory sequences
    Patent number: 6891031
    Abstract: The present invention provides CNS sequences that regulate the cytokine gene expression, expression cassettes and vectors comprising or lacking the CNS sequences, host cells and non-human transgenic animals comprising the CNS sequences or lacking the CNS sequences. The present invention also provides methods for identifying compounds that modulate the functions of CNS sequences as well as methods for diagnosing defects in the CNS sequences of patients.
    Type: Grant
    Filed: February 20, 2001
    Date of Patent: May 10, 2005
    Assignee: The Regents of the University of California
    Inventors: Kelly A. Frazer, Edward M. Rubin, Gabriela G. Loots
  • Coordinate cytokine regulatory sequences
    Publication number: 20020132290
    Abstract: The present invention provides CNS sequences that regulate the cytokine gene expression, expression cassettes and vectors comprising or lacking the CNS sequences, host cells and non-human transgenic animals comprising the CNS sequences or lacking the CNS sequences. The present invention also provides methods for identifying compounds that modulate the functions of CNS sequences as well as methods for diagnosing defects in the CNS sequences of patients.
    Type: Application
    Filed: February 20, 2001
    Publication date: September 19, 2002
    Inventors: Kelly A. Frazer, Edward M. Rubin, Gabriela G. Loots